题  目：Multiscale Investigation of Red Blood Cells: Model Development and Applications

时  间：2021年05月28日10：00－11：30

地  点：腾讯会议ID：726 563 123

会议直播：https://meeting.tencent.com/l/5XY3L1AlzAs1

报告人：Qiang Zhu教授（加利福尼亚大学圣迭戈分校）

欢迎广大师生参加

                           土木与交通学院

                           2021年05月26日

报告人简介：

Qiang Zhu got his PhD in applied mechanics from the Massachusetts Institute of Technology. He is currently a professor in the University of California San Diego. His research focuses on fluid-structure interaction problems in ocean engineering, bioinspired engineering, and biomedical research. His research lab homepage can be found: http://fessrg.ucsd.edu/

报告摘要：

Erythrocytes, also known as red blood cells or RBCs, play important physiological roles in the transportation of oxygen and carbon dioxide around the body. These cells have a well-documented molecular architecture including a composite membrane and cytosol inside. We have developed a molecular-detailed model of the cell membrane based on a multiscale algorithm. This structural model is then combined with a Stokes-flow-based fluid dynamics model to study dynamics of RBCs in vivo or in vitro. With this model we have studied several canonical problems. In this talk I will focus on one of them, the vesiculation of RBCs, which is an important physiological procedure in the cell metabolism and aging process. I will show that based on model predictions we have developed a high-throughput experimental technique that is able to study this process in physiologically relevant conditions.