科研项目

1、中国博士后科学基金面上资助项目（主持）：酿酒酵母重组蛋白酶前导肽加工元件挖掘及合成途径优化研究，2025-01 至 2026-12，2024M760943

2、国家重点研发计划课题（参与）：高效微生物细胞工厂的构建及产品验证，2021-07至 2024-06，2021YFC2100503

3、广东省重点领域研发计划项目（参与）：广式高盐稀态酱油酿造关键技术创新及减盐酿造技术研究与示范，2019.11至2022.12，2020B020226009

4、广州市基础研究计划项目（参与）：酿酒酵母蛋白分泌压力的动态响应及调节，2020-04 至 2023-03，202002030337 

学术论文

1. Chufan Xiao*, Xiufang Liu*, Yuyang Pan, Yanling Li, Ling Qin, Zhibo Yan, Yunzi Feng, Mouming Zhao, Mingtao Huang. Tailored UPRE2 variants for dynamic gene regulation in yeast [J], PNAS, 2024, 121(19): e2315729121. 

2. Xiufang Liu, Feiran Li, Chufan Xiao, Yixin Yu, Lin Zheng, Mouming Zhao, and Mingtao Huang. Rational Design and Model Predictions for Optimized Elastase Production in Saccharomyces cerevisiae [J], ACS Synthetic Biology, 2025, 14(5): 1719-1731.

3. Xiufang Liu, Qian Lu, Han Xiao, Yunzi Feng, Guowan Su, Mouming Zhao, Mingtao Huang. Expression of a salt-tolerant pseudolysin in yeast for efficient protein hydrolysis under high-salt conditions [J], Biomolecules, 2023, 13(1): 83.

4. Xiufang Liu, Mulin Lian, Mouming Zhao, Mingtao Huang. Advances in recombinant protease production: current state and perspectives [J], World Journal of Microbiology and Biotechnology, 2024, 20(144): 144.

5. Xiufang Liu, Chufan Xiao, Xinpeng Yu, Lin Zheng, Mouming Zhao, Mingtao Huang. Peptone source effects on recombinant protease production and cellular responses in yeast [J], Enzyme and Microbial Technology, 2025, 189:110674.

6. Qisen Xiang, Xiufang Liu, Junguang Li, Shengnan Liu, Hua Zhang, and Yanhong Bai. Effects of dielectric barrier discharge plasma on the inactivation of Zygosaccharomyces rouxii and quality of apple juice [J]. Food chemistry, 2018, 254: 201-207.

7. Qisen Xiang, Xiufang Liu, Shengnan Liu, Yunfang Ma, Chunqing Xu, and Yanhong Bai. Effect of plasma-activated water on microbial quality and physicochemical characteristics of mung bean sprouts [J]. Innovative Food Science & Emerging Technologies, 2019, 52: 49-56.

8. Qisen Xiang, Xiufang Liu, Junguang Li, Tian Ding, Hua Zhang, Xiangsheng Zhang, and Yanhong Bai. Influences of cold atmospheric plasma on microbial safety, physicochemical and sensorial qualities of meat products [J]. Journal of Food Science and Technology, 2018, 55: 846-857.

9. Songlyu Xue, Xiufang Liu, Yuyang Pan, Chufan Xiao, Yunzi Feng, Lin Zheng, Mouming Zhao, Mingtao Huang. Comprehensive Analysis of Signal Peptides in Saccharomyces cerevisiae Reveals Features for Efficient Secretion [J], Advanced Science, 2022, 10(2): 2203433.

10. Han Xiao, Xiufang Liu, Yunzi Feng, Lin Zheng, Mouming Zhao, Mingtao Huang. Secretion of collagenases by Saccharomyces cerevisiae for collagen degradation [J], Biotechnology for biofuels and bioproducts, 2022, 15(1): 89.

11. Liumin Fan, Xiufang Liu, Yunfang Ma, and Qisen Xiang. Effects of plasma-activated water treatment on seed germination and growth of mung bean sprouts [J]. Journal of Taibah University for Science, 2020, 14(1): 823-830.

12. Junguang Li, Qisen Xiang, Xiufang Liu, Tian Ding, Xiangsheng Zhang, Yafei Zhai, and Yanhong Bai. Inactivation of soybean trypsin inhibitor by dielectric-barrier discharge (DBD) plasma [J]. Food chemistry, 2017, 232: 515-522.

13. Chufan Xiao, Songlyu Xue, Yuyang Pan, Xiufang Liu, Mingtao Huang. Overexpression of genes by stress-responsive promoters increases protein secretion in Saccharomyces cerevisiae [J], World Journal of Microbiology and Biotechnology, 2023, 39(8): 203.

14. Ling Qin, Yuyang Pan, Songlyu Xue, Zhibo Yan, Chufan Xiao, Xiufang Liu, Dan Yuan, Jin Hou, and Mingtao Huang. Multi-Omics Analysis Reveals Impacts of LincRNA Deletion on Yeast Protein Synthesis [J]. Advanced Science, 2025, 12(13):2406873.

15. Xiao, Chufan, Xiufang Liu, and Mingtao Huang. Synthetic Promoter Design and Functional Evaluation in Saccharomyces cerevisiae, Synthetic Promoter [M]. Springer, 2024, 2844: 97-108.

获奖情况

智能高效蛋白表达平台的创建及应用，第二届粤港澳大湾区博士博士后创新创业大赛-创新赛铜奖，黄明涛；李媛媛; 刘秀妨；肖楚凡；薛松绿；颜志波