流动站在站博士后

基本信息
颜志波

合作导师:黄明涛

电子邮箱:hzb971106@scut.edu.cn

通讯地址:广州市番禺区外环东路382号华南理工大学大学城校区B13号楼505-2

个人简介

颜志波,博士,助理研究员。2011至2015年就读于江西师范大学生物科学专业,获理学学士学位;2015至2018年及2018至2022年分别就读于中山大学动物学和微生物学专业,获理学硕士、博士学位。近年来,在微生物代谢工程与合成生物学领域从事微生物细胞工厂的构建、优化及机制解析相关研究工作,并在领域内权威学术期刊上发表了多项研究成果,受邀担任Bioresource Technology和Synthetic and Systems Biotechnology等专业学术期刊审稿人。

科研项目

(1).国家自然科学基金委员会,面上项目,32471482,构建高效分泌胶原蛋白酶的酿酒酵母及其代谢机制研究,2025-01至 2028-12,在研,参与

(2).国家自然科学基金委员会,面上项目,32071422,氧化应激与病毒样颗粒囊泡工程构建高效人工大肠杆菌及其机制的研究,2021-01 至 2024-12,结题,参与

(3).广东省自然科学基金管理委员会,博士启动纵向协同项目,2018A030310255,进化工程与动态调控大肠杆菌生产紫檀芪的研究,2018-05 至 2021-05,结题,参与

学术论文

(1). Zhibo Yan#, Yuyang Pan#, Mingtao Huang, Jian-Zhong Liu*. De novo pterostilbene production from glucose using modular coculture engineering in Escherichia coli. Journal of Agricultural and Food Chemistry 2023, 72 (1), 516-528.

(2). Yuyang Pan#, Zhibo Yan#, Songlyu Xue, Chufan Xiao, Guangjian Li, Wenyong Lou, Mingtao Huang*. Optimizing the biosynthesis of dihydroquercetin from naringenin in Saccharomyces cerevisiae. Journal of Agricultural and Food Chemistry 2024, 72 (9), 4880-4887.

(3). Zhibo Yan, Jing-Long Liang, Fu-Xing Niu, Yu-Ping Shen, Jian-Zhong Liu*. Enhanced production of pterostilbene in Escherichia coli through directed evolution and host strain engineering. Frontiers in Microbiology 2021, 12, 710405.

(4). Ling Qin, Yuyang Pan, Songlyu Xue, Zhibo Yan, Chufan Xiao, Xiufang Liu, Dan Yuan, Jin Hou, Mingtao Huang*. Multi-omics analysis reveals impacts of LincRNA deletion on yeast protein synthesis. Advanced Science 2025, 12, 2406873.

(5). Chufan Xiao#, Xiufang Liu#, Yuyang Pan, Yanling Li, Ling Qin, Zhibo Yan, Yunzi Feng, Mouming Zhao, Mingtao Huang*. Tailored UPRE2 variants for dynamic gene regulation in yeast. Proceedings of the National Academy of Sciences of the United States of America 2024, 121 (19), e2315729121.

(6). Fu-Xing Niu, Zhibo Yan, Yuan-Bin Huang, Jian-Zhong Liu*. Cell-free biosynthesis of chlorogenic acid using a mixture of chassis cell extracts and purified Spy-cyclized enzymes. Journal of Agricultural and Food Chemistry 2021, 69 (28), 7938-7947.

(7). Yu-Ping Shen, Lai San Fong, Zhibo Yan, Jian-Zhong Liu*. Combining directed evolution of pathway enzymes and dynamic pathway regulation using a quorum-sensing circuit to improve the production of 4-hydroxyphenylacetic acid in Escherichia coli. Biotechnology for Biofuels 2019, 12, 94.

(8). Yu-Ping Shen, Yu-Ling Liao, Qian Lu, Xin He, Zhibo Yan, Jian-Zhong Liu*. ATP and NADPH engineering of Escherichia coli to improve the production of 4-hydroxyphenylacetic acid using CRISPRi. Biotechnology for Biofuels 2021, 14 (1).

(9). Yu-Ping Shen, Fu-Xing Niu, Zhibo Yan, Lai San Fong, Yuan-Bin Huang, Jian-Zhong Liu*. Recent advances in metabolically egineered microorganisms for the production of aromatic chemicals derived from aromatic amino acids. Frontiers in Bioengineering and Biotechnology 2020, 8, 407.

获奖情况

黄明涛,李媛媛,刘秀妨,肖楚凡,薛松绿,颜志波,王诗韵,陆奕;智能高效蛋白表达平台的创建及应用;广东省人力资源和社会保障厅;第二届粤港澳大湾区博士博士后创新创业大赛-创新赛铜奖