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基本信息
游丽君

学  位:博士

导师情况:博导、硕导

研究方向:生物活性多糖、多酚、多肽的分离鉴定、
功效评价和作用机制

联系电话:020-87113848

电子邮箱:feyoulijun@scut.edu.cn

通讯地址:广州市天河区五山路381号

个人简介

游丽君,女,博士,籍贯福建省,广东省杰出青年。现为华南理工大学食品科学与工程学院教授,博士生导师/硕士生导师、食品科学系副系主任,2015年广东省特支计划青年拔尖人才专项入选者、2015广东省优秀青年教师计划入选者、2015年广州市珠江科技新星专项入选者。2010年8月份留校工作,2013年3月破格晋升为副研究员、硕士生导师,2016年破格晋升为博士生导师,是省部科技特派员,是多个国际顶级食品期刊的特约审稿人。于2009年和2016年被国家留学基金委公派至美国康奈尔大学进行访问交流。

目前主要从事生物活性多糖(调节肠道菌群、降血糖、降血脂、抗紫外辐射、提高免疫力等)、多酚(抗癌、降血脂)、多肽(抗氧化、抗疲劳)的分离鉴定、功效评价和作用机制方面的研究。主持国家自然科学基金2项、省部级项目5项、教育部中央高校基本科研业务费专项3项、主持企业横向项目4项。第一作者/通讯作者文章共50多篇,其中被SCI/EI收录35篇(二区以上论文25篇,两篇论文入选ESI高被引论文),申请专利13项,其中授权10项。成果《中草药活性多糖快速筛选、制备关键技术及产业化应用》通过广东省科技成果鉴定并于2017年获得广东省科学技术奖励一等奖。该成果于2015年获江门市科学技术奖励特等奖。

科研项目

主持国家自然科学基金2项、省部级项目5项、教育部中央高校基本科研业务费专项3项、主持企业横向项目4项。

1.国家自然科学基金,抗疲劳肽的构效关系及抗疲劳与抗氧化活性的相关性研究,2012.1-2014.12;

2.广东省特支计划青年拔尖人才项目,2016.6-2019.5;

3.广州市珠江科技新星,龙须菜多糖拮抗皮肤光老化的作用机制及构效关系研究,2016.5-2018.4;

4.广东省自然科学基金团队项目(核心成员),全谷物糙米中游离态和结合态酚类物质调节脂质代谢作用机制,2016.6-2021.6;

5.广东省自然科学基金,海藻多糖对光老化皮肤基质胶原降解的拮抗机制研究,2015.1-2018.1

6.广东省科技计划项目,中医经典名方结合现代功能因子保护胃肠道健康机理研究及其产业化发展,2011.1-2013.12;

7.中央高校科研业务费重点项目,海藻多糖抗皮肤光老化的功效及机理研究,2015.7-2017.7;

8.中央高校科研业务费面上项目,海藻多糖高效制备及降血糖机理研究,2013.1-2014.12;

9.企业委托项目,SZ和LY体内外抗氧化活性成分的含量及功效研究,2016.11-2017.10;

10.中山市食品药品监督管理局委托项目,中山市保健食品原料风险分析和防控措施研究,2014.11-2016.11;

11.企业委托项目,YEDT的保湿功效研究,2013.11-2014.10;

12.企业委托项目,灵芝多糖构效关系及工艺研究,2011.10-2012.12。

学术论文

第一作者/通讯作者文章共50多篇,其中被国际一流期刊SCI/EI收录35篇(二区以上论文25篇,两篇论文入选ESI高被引论文)。

1.Yuhui Ye, Desheng Ji, Lijun You*, Lin Zhou, Zhengang Zhao, Cha**nnan (2018). Structural properties and protective effect of Sargassum fusiforme polysaccharides against ultraviolet B radiation in hairless Kun Ming mice. Journal of Functional Foods, 43, 8-16.

2.Guiqing Zheng, Jie Deng, Lingrong Wen, Lijun You*, Zhengang Zhao, Lin Zhou (2018). Release of phenolic compounds and antioxidant capacity of Chinese hawthorn “Crataegus pinnatifida” during in vitro digestion. Journal of Functional Foods, 40:76-85.

3.Averrhoa carambola free phenolic extract ameliorates nonalcoholic hepatic steatosis by modulating mircoRNA-34a, mircoRNA-33 and AMPK pathway in leptin receptor-deficient db/db mice (2017). Food & Function, 8(12): 4496-4507.

4.Desheng Ji, Lijun You*, Yinglang Ren, Lingrong Wen, Guiqing Zheng (2017). Protective effect of polysaccharides from Sargassum fusiforme against UVB-induced oxidative stress in HaCaT human keratinocytes. Journal of Functional Foods, 36,332-340

5.Yuhui Ye, Dongxiao Sun-Waterhouse, Lijun You*, Arshad Mehmood Abbasi (2017). Harnessing food-based bioactive compounds to reduce the effects of ultraviolet radiation: a review exploring the link between food and human health. International Journal of Food Science and Technology, 52(3), 595-607.

6.Lingrong Wen, Ruixue Guo, Lijun You*, Arshad Mehmood Abbasi, Tong Li, Xiong Fu, Rui Hai Liu (2017). Major triterpenoids in Chinese hawthorn “Crataegus pinnatifida” and their effects on cell proliferation and apoptosis induction in MDA-MB-231 cancer cells, Food and Chemical Toxicology, 100, 149-160.

7.Lingrong Wen, Yunlin Zhang, Dongxiao Sun-Waterhouse, Lijun You* and Xiong Fu (2017). Advantages of the polysaccharides from Gracilaria lemaneiformis over metformin in antidiabetic effects on streptozotocin-induced diabetic mice, RSC Advances, 7(15), 9141-9151.

8.Yinglang Ren, Guiqing Zheng, Lijun You*, Lingrong Wen, Chao Li, Xiong Fu, Lin Zhou (2017). Structural characterization and macrophage immunomodulatory activity of a sulfated polysaccharide isolated from Gracilaria lemaneiformis. Journal of Functional Foods. 33, 286-296

9.Daorui Pang, Lijun You*, Tong Li, Lin Zhou, Dongxiao Sun-Waterhouse, Rui Hai Liu* (2016). Phenolic profiles and chemical- or cell-based antioxidant activities of four star fruit (Averrhoa carambola) cultivars , RSC Advance, 6(93), 90646-90653.

10.Chao Li, Xiangshi, Li, Lijun You*, Xiong Fu*, Rui Hai Liu (2017). Fractionation, preliminary structural characterization and bioactivities of polysaccharides from Sargassum pallidum, Carbohydrate Polymers, 155, 261-270.

11.Lingrong Wen, Guiqing Zheng, Lijun You *, Arshad Mehmood Abbasi, Tong Li, Xiong Fu, Rui Hai Liu* (2016). Phytochemical profiles and cellular antioxidant activity of Malus doumeri (bois) chevalier on 2,2-azobis (2-amidinopropane) dihydrochloride (ABAP)-induced oxidative stress. Journal of Functional Foods, 25, 242-256.

12.Chao Li, Qiang Huang, Jie Xiao, Xiong Fu*, Lijun You*, Rui Hai Liu (2016). Preparation of Prunella vulgaris polysaccharide-zinc complex and its antiproliferative activity in HepG2 cells. International Journal of Biological Macromolecules, 91, 671-679.

13.Chun Chen, Bin Zhang, Xiong Fu *, Li-Jun You*, Arshad Mehmood Abbasi , Rui Hai Liu (2016). The digestibility of mulberry fruit polysaccharides and its impact on lipolysis under simulated saliva, gastric and intestinal conditions, Food Hydrocolloids, 58, 171-178.

14.Lingrong Wen , Qing Gao , Chung-wah Ma , Yazhong Ge , Lijun You*, Rui Hai Liu , Xiong Fu , Dong Liu (2016). Effect of polysaccharides from Tremella fuciformis on UV-induced photoaging. Journal of Functional Foods,20, 400-410.

15.Lingrong Wen, Xingbo Guo, Rui Hai Liu*, Lijun You*, Arshad Mehmood Abbasi, Xiong Fu (2015). Phenolic contents and cellular antioxidant activity of Chinese hawthorn Crataegus pinnatifida. Food Chemistry, 186(SI):54-62.

16.Chao Li, Qiang Huang, Xiong Fu*, Xiujie Yue, Rui Hai Liu, Lijun You*. Characterization, antioxidant and immunomodulatory activities of polysaccharides from Prunella vulgaris Linn. International Journal of Biological Macromolecules, 2015, 75, 298-305.

17.Chao Li, Xiong Fu*, Qiang Huang, Faxing Luo, Lijun You* (2015). Ultrasonic extraction and structural identifcation of polysaccharides from Prunella vulgaris and its antioxidant and antiproliferative activities. European Food Research and Technology, 240(1), 49-60.

18.Wei Zhang, Chao Li, Lijun You*, Xiong Fu*, Yongsheng Chen, & Yuqin Luo (2014). Structural identification of compounds from Toona sinensis leaves with antioxidant and anticancer activities. Journal of Functional Foods, 10, 427-435.

19.Lijun You, Jiaoyan Ren, Bao Yang, Joe Regenstein, Mouming Zhao* (2012). Antifatigue activities of loach protein hydrolysates with different antioxidant activities. Journal of Agricultural and Food Chemistry, 60(50), 12324-12331.

20.Antioxidant and antiproliferative activities of loach (Misgurnus anguillicaudatus) peptides prepared by papain digestion. Journal of Agricultural and Food Chemistry, 59(14), 7948-7953.

21.Lijun You, Qing Gao, Mengying Feng, Bao Yang, Jiaoyan Ren, Longjian Gu, Chun Cui, Mouming Zhao* (2013). Structural characterisation of polysaccharides from Tricholoma matsutake and their antioxidant and antitumor activities. Food Chemistry, 138(4), 2242-2249.

22.Lijun You, Mouming Zhao*, Joem Regenstein, Jiaoyan Ren (2011). In vitro antioxidant activity and in vivo anti-fatigue effect of loach (Misgurnus anguillicaudatus) peptides prepared by papain digestion. Food Chemistry, 124(1), 188-194.

23.Lijun You, Mouming Zhao*, Joe Regenstein, Jiaoyan Ren (2010). Changes in the antioxidant activity of loach (Misgurnus anguillicaudatus) protein hydrolysates during a simulated gastrointestinal digestion. Food Chemistry, 120(3), 810-816.

24.Lijun You, Mouming Zhao*, Joem Regenstein, Jiaoyan Ren (2010). Purification and identification of antioxidant peptides from loach protein hydrolysate by consecutive chromatography and electrospray ionization-mass spectrometry. Food Research International, 43(4), 1167-1173.

25.Lijun You, Mouming Zhao*, Chun Cui, Haifeng Zhao, Bao Yang. (2009) .Effect of degree of hydrolysis on the antioxidant activity of loach (Misgurnus anguillicaudatus) protein hydrolysates. Innovative Food Science and Emerging Technologies, 10(2), 235-240.

26.Optimization of hydrolysis conditions for the production of antioxidant peptides from fish gelatin using response surface methodology (RSM). Journal of Food Science, 75(6), C582-C587.

27.Lijun You, Lin Zheng, Joe M. Regenstein, Mouming Zhao*, Dong Liu (2012). Effect of thermal treatment on the characteristic properties of loach peptide. International Journal of Food Science and Technology, 47(12), 2574-2581.

28.Chung-wah Ma, Mengying Feng, Xufeng Zhai, Minghua Hu, Lijun You*, Wei Luo, Mouming Zhao (2013). Optimization for the extraction of polysaccharides from Ganoderma lucidum and their antioxidant and antiproliferative activities. Journal of the Taiwan Institute of Chemical Engineers, 44(6), 886-894. 2.637二区

29.Lijun You, Yuzhe Li, Haifeng Zhao, Joe Regenstein, Mouming Zhao*, Jiaoyan Ren (2015). Purification and characterization of an antioxidant protein from pearl oyster (Pinctada fucata martensii), Journal of Aquatic Food Product Technology, 24(7), 661–671

30.游丽君,刘敏,林恋竹,赵谋明.载荷槲皮素的酪蛋白纳米粒子输送载体的构建,华南理工大学学报(自然科学版),2017,45(3), 138-145. (EI收录)

31.赵谋明,邹林武,游丽君*.提取方法对香菇多糖性质的影响(2013).华南理工大学学报(自然科学版),41(10), 26-33(EI收录)

32.游丽君,冯梦莹,刘钧发,赵强忠,罗维,赵谋明.不同提取方法对灵芝多糖性质的影响研究(2013).现代食品科技,29(6),1207-1212. (EI收录)

33.游丽君,刘钧发,冯梦莹,赵谋明.酶法水解金针菇多糖及其产物特性分析(2013).现代食品科技,29(7),1486-1490. (EI收录)

34.游丽君,邹林武,梁彦豪,赵谋明.超声-高温热水提取香菇多糖及其产物特性研究(2013).现代食品科技,29(9), 2167-2246. (EI收录)

35.游丽君,赵谋明,Joe Regenstein,任娇艳,阮微媚.加工和贮藏条件对泥鳅多肽抗氧化活性的影响(2009).江苏大学学报(自然科学版),30(6),549-553. (EI收录)

获奖

1.成果《中草药活性多糖快速筛选、制备关键技术及产业化应用》通过广东省科技成果鉴定并于2017年获得广东省科学技术奖励一等奖(排名第8)。该成果于2015年获江门市科学技术奖励特等奖。

2.2015年广东省特支计划青年拔尖人才;

3.2015年广东省优秀青年教师;

4.2015年广州市珠江科技新星;

5.“挑战杯”课外学术科技作品竞赛省赛一等奖的指导教师。

6.优秀研究生级主任。

教授

联系方式

学院办公室:020-87113126
科研工作:020-87114218
教务工作:020-87110738
实验室管理:020-87113034
本科学工:020-87113037
组织人事:020-22236011