时间：2016年9月5日（星期一）下午15：00
报告地点：材料科学与工程学院25号楼331会议室

报告摘要：
       This lecture gives an overview of our recent research activities on functional polymers made from amino acids and sugars. Special focus is put on three topics:
       (1) Statistical copolypeptides based on allylglycine and -benzyl-l-glutamate were prepared by ring-opening copolymerization of corresponding amino acid N-carboxyanhydrides. The allylglycine units were functionalized with 2,3,4,6-tetra-O-acetyl-1-thio--d-glucopyranose applying thiol-ene “click” photochemistry. Removal of the protecting groups yielded glycosylated poly(l-glutamate)s, which were capable of recognizing proteins (specific carbohydrate-lectin interactions) and changing solution properties (ionization and conformation) in dependence of solution pH.
       (2) Poly(-benzyl-l-glutamate-co-allylglycine) formed organogels at < 2% w/v in toluene, tetrahydrofuran, or 1,4-dioxane, assisted by UV-crosslinking with dithiol. Debenzylation of dioxane gels yielded highly absorbent and pH-responsive poly(l-glutamate) hydrogels, which are attractive materials for biomedical applications.
       (3) Multi-heterofunctional poly(ester-disulfide-alkene)s were prepared by metathesis polymerization of l-cystine based macrocycles. Monomer conversion reached ~80% in equilibrium and the produced polymers exhibited high apparent molar masses (Mwapp) of up to 80 kDa and dispersities (Ð) of ~2. The polymers can be further functionalized with acid anhydrides and degraded by reductive cleavage of the main-chain disulfide.
附报告人简介：
       报告人毕业于德国美因茨大学（Johannes Gutenberg-University Mainz），分别于1993年和1997年获得化学专业学士学位和博士学位；1997-1999年于美国麻省大学卢维尔分校（University of Massachusetts at Lowell）进行博士后研究工作；1999年起于德国马普胶体与界面研究所（Max-Planck Institute of Colloids and Interfaces）任课题组长，并于2004年获得德国教授资格；2014年加入同城的波茨坦大学任教授。Schlaad教授研究的范围涵盖高分子和胶体化学的诸多方面，包括活性（离子型/自由基/开环）聚合、有机小分子催化聚合、高分子点击化学、高分子光化学、刺激相应性高分子胶体、双亲水性嵌段共聚物，高分子-高分子复合物、仿生高分子、高分子多级结构、聚肽类高分子、含糖高分子等。至今共发表学术论文近200篇和11篇书籍章节；是国际高分子核心专业期刊《Polymer International》的副主编，《Reactive and Functional Polymers》、《Polymers》的编委以及《Polymer Chemistry》、《Macromolecular Rapid Communications》、《Macromolecular Bioscience》的顾问编委。