报告题目:Using Biological Materials and Mechanisms to Biofabricate an Interface between Biology and Electronics
报告人:Gregory F. Payne教授
报告时间:2014年6月19日,9:00-11:00
报告地点:制浆造纸工程国家重点实验室306会议室
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华南理工大学
制浆造纸工程国家重点实验室
2014年6月16日
报告人简介:
Gregory F. Payne是美国马里兰大学铂克分校教授,他的主要研究方向为生物构造(Biofabrication)技术,天然高分子材料,生物酶功能化研究,生物传感器和生物芯片。他在Science、Advanced Materials、Advanced Functional Materials、Biomaterials、Soft Matter、Lab on a Chip等国际权威期刊发表了130多篇高水平的研究论文,也被邀请出席了大量的国际学术会议和报告,并被国内武汉大学、华东科技大学等高校聘为“客座教授”。他担任了多届的国际甲壳素和壳聚糖会议的国际顾问委员会委员、科学委员会委员。美国国立卫生研究院(NIH)的肌肉骨骼组织工程(2004-2009),组织工程(2005),血液学(2005)等部门的特别委员会委员,并担任多届的欧洲甲壳素协会的国际顾问委员会委员、科学委员会委员以及国际咨询委员会委员。
Gregory F. Payne received his B.S. and M.S. degrees in Chemical Engineering from Cornell University in 1979 and 1981, respectively. He received his Ph.D. in Chemical Engineering from The University of Michigan in 1984. After completing his Ph.D., he returned to Cornell to do post-doctoral work with Michael Shuler in biochemical engineering. In 1986 Prof. Payne joined the faculty of the University of Maryland where he is currently a Professor jointly-appointed in the Institute for Bioscience and Biotechnology Research and the Fischell Department of Bioengineering. His research is focused on biofabrication – the use of biological or biomimetic materials and mechanisms to confer structure and function to materials. Specifically, his group biofabricates using enzymes and biologically-derived polymers such as chitosan. Prof. Payne has published over 130 peer-reviewed journal papers, been awarded 6 US patents, served on the advisory board of numerous international symposia and study sections, and received the University of Maryland Regents Award for research, scholarship and creative activity. Currently, he spends 6 months per year in China where he is Guest Professor at Wuhan University and Chair Professor at East China University of Science and Technology.
学术报告简介:
Advances in biology and microelectronics transformed our lives over the last 50 years and there remains considerable opportunity to createsynergies between these two fields. For instance, the effective interfacing of biological and electronic systems could enable remarkable capabilities for sensing (disease diagnosis and monitoring), energy harvesting (biofuel cells) and medicine (neuroprosthetics). Through a network of local and international collaborations, we are examining two challenges to bio-device integration – constructing the physical interface and establishing communication across this interface. In both cases, we are applying the materials and mechanisms from biology toaddress these challenges.
To construct a bio-device interface we employ stimuli-responsive hydrogel-forming biopolymers (especially polysaccharides) that can be triggered to self-assemble at electrode addresses in response to electrode-imposed signals. The hydrogel films assembled at the electrode can be bio-functionalized to offer cellular functions or modified with proteins to offer molecular functions. Communication across this interface is achieved usinga redox-active film that is fabricated by catechol modification of a polysaccharide film. This redox-active (but non-conducting) film can accept redox information from biology and transmit this information to the electronics. These studies demonstrate that biology offers unique materials and mechanisms for the “fusion” of biology and electronics.