关于举行新加坡南洋理工大学 Sing Yian CHEW教授学术报告会的通知
报告题目：Engineering Extracellular Microenvironments to Direct Nerve Repair
报 告 人：Sing Yian CHEW（ 教授 新加坡南洋理工大学）
主 持 人：王均教授
报告时间：2025年10月21日（星期二）9:30-12:00
报告地点：华南理工大学广州国际校区C1b-115
主办单位：生物医学科学与工程学院
生物医学科学与工程学院
2025年10月14日
报告人简介：
Dr. Sing Yian CHEW is a Professor at the School of Chemistry, Chemical Engineering and Biotechnology, the Lee Kong Chian School of Medicine and the School of Materials Science and Engineering at Nanyang Technological University, Singapore. She is also an International Fellow of Tissue Engineering and Regenerative Medicine (FTERM). Dr. Chew is known for her contributions in designing biomimetic scaffolds to understand and control cell fate. Her most significant contribution is in the field of scaffold-mediated delivery of gene-silencing and biomimicking physical signals for neural tissue regeneration and remyelination.Dr.Chew is an Associate Editor at ACS Applied Materials & Interfaces. She also serves as the editorial board member of Biomaterials, Experimental Neurology,Tissue Engineering,Journal of Biomedical Materials Research,Part A, Drug Delivery and Translational Research.
报告摘要：
The extracellular matrix (ECM) microenvironment is a key regulator of cell fate and tissue regeneration. By designing tissue-engineered scaffolds that emulate the essential biophysical and biochemical features of the natural ECM, we can better direct cellular behavior and promote functional tissue outcomes. In this presentation, I shall discuss our recent work on engineering biofunctional scaffolds integrated with biomolecular cues, highlighting the use of RNA interference to enhance nerve regeneration and remyelination. I shall also present findings from our studies on human spinal cord progenitor cell transplantation for spinal cord injury repair. Particular emphasis will be placed on fiber-based constructs that recapitulate the architecture and size-scale of the native ECM, as well as 3D-printed scaffolds that enable customizable and application-specific designs.