2023—至今 华南理工大学生物医学科学与工程学院 教授
2019—2023 香港中文大学 博士后
2015—2019 香港中文大学生物医学工程系 博士
2011—2015 山东大学 学士生物医学工程（学博、学硕）、生物学（学博、学硕）、材料与化工（工程博士）、生物与医药（工程硕博）
生物材料、液-液相分离凝聚体、水凝胶、组织工程与再生医学
液-液相分离（Liquid-liquid phase separation）驱动的凝聚体（Coacervate）及其相变行为，构成了一类跨越分子、亚细胞乃至组织尺度的普适性自组装机制。凝聚体有望作为一类可被设计与工程化的新型液体生物材料，但面临结构稳定性差及分子组成-理化性质-生物医学功能构效关系不明等挑战。课题组聚焦多价弱相互作用驱动的凝聚体结构设计，探究凝聚体以及凝聚体-水凝胶相变应用于细胞/组织仿生、药物递送载体、疾病免疫治疗、组织工程与再生医学等领域的功效机制，致力于为凝聚体作为液体生物材料确立普适性设计原则。在Nat. Chem.、Nat. Biomed. Eng.、Sci. Adv.、Nat. Commun.、J. Am. Chem. Soc.、Angew. Chem. Int. Ed.、Adv. Mater.等期刊以通讯作者或第一作者发表论文20余篇。主持国家自然科学基金优青（海外）项目、国家重点研发计划课题、国家自然科学基金面上项目等。
研究团队网站：https://www.x-mol.com/groups/bian_lab/people
代表性论文
1. +Sirong Chen, +Tianshen Jiang, Xiaorou Qiu, Ruitong Luo, Haiyang Yao,Ruinan Wang, Zhuo Li, *Pengchao Zhao, *LimingBian. Cartilage-binding coacervate as biomimetic therapeutics-ladenlubricant alleviates osteoarthritis by reducing joint friction and inflammation. NatureBiomedical Engineering, 2026.
2. +Bo Yi, +Hao Li, Sirong Chen, Honghui Lian, Fengming Tan, HaiyangYao, Xiayi Xu, *Kunyu Zhang, *Pengchao Zhao, *Liming Bian. Superspreadingand ultra-infiltrative coacervate mediates strong underwater adhesion onhydrated and lipidic substrates. Nature Chemistry, 2026.
3.+Xian Xie, +Tianjie Li, Linjie Ma, Jiahao Wu, Yajing Qi, BoguangYang, Zhuo Li, Zhinan Yang, Kunyu Zhang, Zhiqin Chu, To Ngai, JiangXia, *YiWang, *Pengchao Zhao, *Liming Bian. A designer minimalistic modelparallels the phase separation-mediated assembly and biophysical cues ofextracellular matrix. Nature Chemistry, 2025, 17,1216.
4. +Jianyang Zhao, +Yuan Hu, +Caikun Liu, Chenchen Yan,Zhiqiang Liu, Zekun Chen, Zhiqiang Nie, *Xaixi Xu, *Miao Cui,*Pengchao Zhao, *Liming Bian. Tissue-conforming organoselenium hydrogelwith microphase-controlled acylhydrazone crosslinking kinetics expeditesdiabetic wound healing by inhibiting AGE-RAGE pathways. Advanced Materials, 2026, e72776.
5.+Ruinan Wang, +Hao Li, +Bo Yi, Sirong Chen, Qiangjun Ling, TianshengJiang, Hao Fu, *Xuefeng Yang, *Pengchao Zhao, *Liming Bian. Enhanced biofilminfiltration by drug-laden coacervate for treating refractory infections. Advanced Materials, 2026, e21500.
6. Qingqiao Xie, Chenchen Yan, Zifeng Yang, Xiayi Xu, *Yong Li, *PengchaoZhao, *Liming Bian. Fluidic microgel assemblies with enhanced oraldelivery of biologics alleviate colonic inflammation in murine and caninemodels. ScienceAdvances, 2025, eadv6994.
7. +Tianshen Jiang, +Sirong Chen, +Jingwen Xu, Yuxiao Zhang, HaoFu, Qiangjun Ling, Yan Xu, Xiangyu Chu, Ruinan Wang, Liangcong Hu, Hao Li,Weitong Huang, *Liming Bian, *Pengchao Zhao, *FuxinWei. Superporous sponge prepared by secondarynetwork compaction with enhanced permeability and mechanical properties fornon-compressible hemostasis in pigs. Nature Communications, 2024, 15, 5460.
8. +Xuefeng Yang, +Boguang Yang, +YingruiDeng, +Xian Xie, Yanwei Qi, Guoqing Yan, Xin Peng, *Pengchao Zhao, *LimingBian. Coacervation-mediated cytocompatibleformation of supramolecular hydrogels with self-evolving macropores for 3D multicellular spheroidculture. Advanced Materials, 2023, 202300636.
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