都小姣 教授

办公电话:

020-39380898

电子邮件:

duxjz@scut.edu.cn

办公地址：

广州国际校区C1-c806

实验室网站链接：https://www2.scut.edu.cn/nanomedicine/yjtdcy/list.htm

2023-至今 华南理工大学 教授

2016-2022 华南理工大学 副教授

2014-2016 中国科学技术大学 生命科学学院 博士后

2009-2014 中国科学技术大学 生命科学学院 博士

2005-2009 郑州大学 生物技术系 学士

纳米药物载体、药物递送、mRNA疫苗

在Proc. Natl. Acad. Sci. U. S. A.、Nano Today、Adv. Mater.、Biomaterials等杂志发表论文37篇，其中，IF＞10论文15篇，（共）第一/通讯作者论文11篇；H-index=23，论文总引用次数>3000次；申请专利3项；主持国家自然科学基金面上项目、广东省自然科学基金面上项目、广州市科学研究计划、校杰出青年项目等，参与国家重点研发计划、973计划等，入选广东省珠江人才计划引进高层次人才青年拔尖人才。

代表性论文   

1. Jilong Wang, Mengwen Huang, Senbiao Chen, Yingli Luo, Song Shen, Xiaojiao Du*, Nanomedicine-mediated ubiquitination inhibition boosts antitumor immune response via activation of dendritic cells, Nano Research, https://doi.org/10.1007/s12274-021-3312-4.

2. Yang Wang^#, Zhu-Xin Gao^#, Xiaojiao Du*, Senbiao Chen, Wangcheng Zhang, Jilong Wang, Hongjun Li, Xinyu He, Jie Cao* and Jun Wang*, Co-inhibition of the TGF-β pathway and the PD-L1 checkpoint by pH-responsive clustered nanoparticles for pancreatic cancer microenvironment regulation and anti-tumor immunotherapy, Biomater. Sci., 2020, 8, 5121-5132.

3. Senbiao Chen^#, Dongdong Li^#, Xiaojiao Du^∗, Xinyu He, Mengwen Huang, Yang Wang, Xianzhu Yang^∗, Jun Wang*, Carrier-free nanoassembly of doxorubicin prodrug and siRNA for combinationally inducing immunogenic cell death and reversing immunosuppression, Nano Today, 2020, 35, 100924.

4. Yan-Hua Zhu, Ji-Long Wang, Hou-Bing Zhang, Malik Ihsanullah Khan, Xiao-Jiao Du* and Jun Wang*, Incorporation of a rhodamine B conjugated polymer for nanoparticle trafficking both in vitro and in vivo, Biomater. Sci., 2019, 7, 1933-1939.

5. Ji-Long Wang, Xiao-Jiao Du*, Jin-Xian Yang, Song Shen, Hong-Jun Li, Ying-Li Luo, Shoaib Iqbal, Cong-Fei Xu, Xiao-Dong Ye, Jie Cao*, Jun Wang*, The effect of surface poly(ethylene glycol) length on in vivo drug delivery behaviors of polymeric nanoparticles, Biomaterials, 2018, 182, 104-113.

6. Xiao-Jiao Du, Ji-Long Wang, Shoaib Iqbal, Hong-Jun Li, Zhi-Ting Cao, Yu-Cai Wang, Jin-Zhi Du, and Jun Wang*, The Effect of Surface Charge on Oral Absorption of Polymeric Nanoparticles, Biomater. Sci., 2018, 6, 642-650.

7. Shoaib Iqbal, Xiaojiao Du*, Jilong Wang, Hongjun Li, Youyong Yuan, and Jun Wang, Surface charge tunable nanoparticles for TNF-α siRNA oral delivery for treating ulcerative colitis, Nano Res., 2018, 11, 2872-2884.

8. Hong-Jun Li^#, Jin-Zhi Du^#, Xiao-Jiao Du^#, Cong-Fei Xu, Chun-Yang Sun, Hong-Xia Wang, Zhi-Ting Cao, Xian-Zhu Yang, Yan-Hua Zhu, Shuming Nie^*, Jun Wang^*, Stimuli-responsive clustered nanoparticles for improved tumor penetration and therapeutic efficacy, Proc. Natl. Acad. Sci. U. S. A., 2016, 113 (15), 4164-4169.

9. Xiao-Jiao Du^#, Ji-Long Wang^#, Wei-Wei Liu^#, Jin-Xian Yang, Chun-Yang Sun, Rong Sun, Hong-Jun Li, Song Shen, Ying-Li Luo, Xiao-Dong Ye*, Yan-Hua Zhu, Xian-Zhu Yang, Jun Wang^*, Regulating the surface poly(ethylene glycol) density of polymeric nanoparticles and evaluating its role in drug delivery in vivo,Biomaterials, 2015, 69, 1-11.

10. Xian-Zhu Yang^#, Xiao-Jiao Du^#, Yang Liu, Yan-Hua Zhu, Yang-Zhong Liu, Ya-Ping Li, and Jun Wang ^*, Rational design of polyion complex nanoparticles to overcome cisplatin resistance in cancer therapy, Adv. Mater., 2014, 26, 931-936.