沈松 副教授 （博导）

省级青年人才项目入选者

办公电话:

  020-81182181

电子邮件:

shensong@scut.edu.cn

办公地址：

广州国际校区C1-c807

实验室网站链接：https://www2.scut.edu.cn/nanomedicine/yjtdcy/list.htm

2019—至今 华南理工大学 生物医学科学与工程学院 副教授 

2017—2019 华南理工大学医学院 博士后

2011—2017 中国科学技术大学 博士

2007—2011 安徽师范大学 学士

生物医学工程（学博、学硕）、生物学（学博、学硕）、材料与化工（工程博士）、药学（专硕）

纳米递送载体、肿瘤免疫治疗、抗体药物

在Nature Communication.、Nano Today、Nano Lett.等国际知名学术期刊共发表论文40余篇，他引2000余次，3篇入围ESI高被引论文，其中第一作者（含共第一）及通讯作者（含共通讯）18篇。申请中国发明专利/PCT专利12项，授权5项；参与撰写2部著作的章节。先后主持广东省自然科学基金杰出青年项目、国家自然科学基金面上项目、青年科学基金以及博士后创新人才支持计划等，作为核心骨干参与国家重点研发计划、广州市重点领域研发计划等项目。

1. Kai-Ge Chen^#, An Liu^#, Cheng-Tao Jiang, Dong-Kun Zhao, Qian-Ni Ye, Yu-Qi Liao, Cong-Fei Xu, Song Shen*, Jun Wang, Dual-functional super bispecific nano-antibodies derived from monoclonal antibodies potentiate the antitumor effect of innate immune cells. Nano Today 2021, 39, 101209.

2. Cheng-Tao Jiang^#, Kai-Ge Chen^#, An Liu, Hua Huang, Ya-Nan Fan, Dong-Kun Zhao, Qian-Ni Ye, Hou-Bing Zhang, Cong-Fei Xu, Song Shen*, Meng-Hua Xiong, Jin-Zhi Du, Xian-Zhu Yang, Jun Wang*, Immunomodulating nano-adaptors potentiate antibody-based cancer immunotherapy. Nature Communications 2021, 12, 1359.

3. Junxia Wang^#, Song Shen^#, Jie Li, Ziyang Cao, and Xianzhu Yang*, Precise Depletion of Tumor Seed and Growing Soil with Shrinkable Nanocarrier for Potentiated Cancer Chemoimmunotherapy. ACS Nano 2021, 15, 4636-4646.

4. Liangjie Jin, Song Shen*, Youju Huang*, Dongdong Li, Xianzhu Yang*, Corn-like Au/Ag nanorod-mediated NIR-II photothermal/photodynamic therapy potentiates immune checkpoint antibody efficacy by reprogramming the cold tumor microenvironment. Biomaterials 2021, 268, 120582.

5. Hua Huang, Cheng-Tao Jiang, Song Shen*, An Liu, Yun-Jiu Gan, Qi-Song Tong, Sen-Biao Chen, Zhu-Xin Gao, Jin-Zhi Du, Jie Cao*, Jun Wang*, Nanoenabled reversal of IDO1-mediated immunosuppression synergizes with immunogenic chemotherapy for improved cancer therapy. Nano Letters 2019, 19, 5356-5365.

6. Jun-Xia Wang^#, Song Shen^#, Dong-Dong Li, Chang-You Zhan, You-Yong Yuan, and Xian-Zhu Yang*, Photoswitchable ultrafast transactivator of transcription (TAT) targeting effect for nanocarrier-based on-demand drug delivery. Advanced Functional Materials. 2018, 28, 1704806.

7. Song Shen^#, Hong-Jun Li^#, Kai-Ge Chen, Yu-Cai Wang, Xian-Zhu Yang, Zhe-Xiong Lian, Jin-Zhi Du*, Jun Wang*, Spatial targeting of tumor-associated macrophages and tumor cells with a pH-sensitive cluster nanocarrier for cancer chemoimmunotherapy. Nano Letters 2017, 17, 3822-3829.

8. Song Shen, Jing-Xing Xia*, Jun Wang*, Nanomedicine-mediated cancer stem cell therapy. Biomaterials 2016, 74, 1-18.

9. Chun-Yang Sun^#, Song Shen^#, Cong- Fei Xu, Hong-Jun Li, Yang Liu, Zhi-Ting Cao, Xian-Zhu Yang, Jing-Xing Xia, and Jun Wang*, Tumor acidity-sensitive polymeric vector for active targeted siRNA delivery. Journal of the American Chemical Society 2015, 137, 15217-15224.

10. Song Shen, Chun-Yang Sun, Xiao-Jiao Du, Hong-Jun Li, Yang Liu, Jing-Xing Xia*, Yan-Hua Zhu, Jun Wang*，Co-delivery of platinum drug and siNotch1 with micelleplex for enhanced hepatocellular carcinoma therapy. Biomaterials 2015, 70, 81-83.