基本信息

边黎明教授

国家级中青年人才项目入选者

办公电话：020-81182189 电子邮件:

bianlm@scut.edu.cn

办公地址：广州国际校区C1-b311

New Innovator Award, IEEE NANOMED, 2019

Mid-career Investigator Award, Chinese Association for Biomaterials, 2019

Rising Star Award, BMES CMBE, 2018

Young Investigator Award, Asian Biomaterial Congress, 2015    

教育与科研工作经历

2021-至今 华南理工大学生物医学科学与工程学院  教授

2018-2021 香港中文大学 生物医学工程学系 长聘副教授

2012-2018 香港中文大学 生物医学工程学系 助理教授

2009-2012 美国宾夕法尼亚大学 生物工程学系 博士后

2004-2009 美国哥伦比亚大学 生物医学工程系 博士

招生学科

生物医学工程（学博、学硕）、生物学（学博、学硕）、材料与化工（工程博士）、药学（专硕）

生物材料、干细胞组织工程、水凝胶

主要致力于可应用于促进受损伤/病变人体组织/器官修复与再生的新型水凝胶支架生物料的开发。围绕现有的用于组织工程的水凝胶还具有生物诱导性不足、缺乏生物活性因子微观尺度呈递优化、缺乏细胞尺度的动态结构、不能有效支持干细胞力学感知及细胞相互作用、限制细胞/组织三维发展等各类问题，近5年内在Science Translational Medicine, Nature Communications, Science Advances, JACS, Advanced Materials, Advanced Functional Materials, Nano letters, ACS Nano, Macromolecules，Biomaterials, Small, ACS Central Science等国际高质量期刊上以通讯作者身份发表论文60余篇

代表性论文列表：

1. +Zhang, K.; +Feng, Q.; Fang, Z.; *Gu, L.; *Bian, L. Structurally dynamic hydrogels for biomedical applications: pursuing a fine balance between macroscopic stability and microscopic dynamics. Chemical Reviews, 2021.

2. +Peng, X.; +Xia, X., +Xu, X.; Yang, X.; Yang, B.; Zhao, P.; Yuan, W.; *Chiu P.W.R.; *Bian, L. Ultra-fast self-gelling powder mediate robust wet adhesion to promote healing of gastrointestinal perforations. Science Advances, 2021, Vol. 7, no. 23, eabe8739

3. +Yang, B.; +Wei, K.; Loebel, C.; Zhang, K.; Feng, Q.; Li, R.; Wong, D.S.H.; Xu, X.; Lau, C.; Chen, X.; Zhao, P.; Yin, C.; Burdick, J.A.; *Wang, Y.; *Bian, L. Enhanced mechanosensing of cells in synthetic 3D matrix with controlled biophysical dynamics. Nature Communications, 2021, Article number: 3514.

4. +Wong, S.H.D.; +Xu, X.; Chen, X., Xing, Y.; Xu, L.; Lai, N.C.H.; Oh, J.; Wong, R.W.K.; Wang, X.; Han, S.; You, W.,  Shuai, X.; Wong, N., *Tan, Y.; *Duan, L.; *Bian, L. Manipulation of the nanoscale presentation of integrin ligand produces cancer cells with enhanced stemness and tumorigenicity. Nano Letters, 2021, 21, 7, 3225–3236.

5. +Zhao, P.; +Yang, B.; Xu, X.; Lai, N.C.H.; Li, R.; Yang, X.; *Bian, L. Nanoparticle-assembled vacuolated coacervates control macromolecule spatiotemporal distribution to provide a stable segregated cell microenvironment. Advanced Materials, 2021, 33, 9, 2007209. 

6. +Xu, X.; +Xia, X.; +Zhang, K.; Rai, A.; Li, Z.; Zhao, P.; Wei, K.; Zou, L.; Yang, B.; Wong, W.K.R., *Chiu, P.W.Y.;*Bian, L. Bioadhesive hydrogels demonstrating pH-independent and ultrafast gelation promote gastric ulcer healing in pigs. Science Translational Medicine 2020, 12, 58, eaba8014.

7. Li, R.; Lin, S.; Zhu, M.; Deng, Y.; Chen, X.; Wei, K.; Xu, J.; Li, G.; *Bian, L. Synthetic presentation of noncanonical Wnt5a motif promotes mechanosensing-dependent differentiation of stem cells and regeneration. Science Advances, 2019, 5: eaaw3896.

8. Chen, X.; Li, R; Wong, S.H.D.; Wei, K.; et al.; Xia, J.; Chen, G..; L., G.; *Bian, L. Conformational manipulation of scale-up prepared single chain polymeric nanogels for multiscale regulation of cells. Nature Communications, 2019, volume 10, Article number: 2075.

9. +Kang, H.; +Yang, B.; Zhang, K.; Pan, Q.; Yuan, W.; Li, G.; *Bian, L. Immunoregulation of macrophages by dynamic ligand presentation via ligand-cation coordination. Nature Communications, 2019, volume 10, Article number: 1696.

10. +Kang, H.; + Jung, H.J.; Wong, S.H.D.; Kim, S.K.; Lin, S.; Chan, K.F.; Zhang, L.; Li, G.; Dravid, V.; *Bian, L. Remote control of heterodimeric magnetic nanoswitch regulates the adhesion and differentiation of stem cells. J. Am. Chem. Soc., 2018;140 (18): 5909-5913.

11. Bian, L.; Guvendiren, M.; Mauck, R.L.; Burdick, J.A. Hydrogels that mimic developmentally relevant matrix and N-cadherin interactions enhance MSC chondrogenesis. Proc. Natl. Acad. Sci. USA.2013 Jun 18; 110(25):10117-22.

 边黎明教授研究团队网站：https://www.x-mol.com/groups/bian_lab?lang=en