王均 教授
办公电话:
020-81182182
电子邮件:
mcjwang@scut.edu.cn
办公地址：广州国际校区C1-c808
国家自然科学基金杰出青年获得者、国家重点研发计划项目负责人
国际生物材料科学与工程会士、英国皇家化学会会士、Biomaterials副主编
国家自然科学基金杰出青年获得者、国家重点研发计划项目负责人
国际生物材料科学与工程会士、英国皇家化学会会士、Biomaterials副主编
2018-至今，华南理工大学生物医学科学与工程学院院长，教授
2018-至今，国家人体组织功能重建工程技术研究中心副主任，研究员
2018-2021，华南理工大学医疗器械研究检验中心，主任
2019-2022，广东省生物医学工程重点实验室，主任
2016-2020，华南理工大学生命科学研究院，教授
2006-2016，中国科学技术大学生命科学学院，教授；合肥微尺度物质科学国家实验室（筹），研究员
2004-2006，中国科学技术大学高分子科学与工程系，教授
2002-2004，约翰霍普金斯大学医学院生物医学工程系，博士后
1999-2002，JohnsHopkinsSingapore，博士后
1993-1998，武汉大学，博士，高分子化学与物理专业
1989-1993，武汉大学，学士，主修化学专业，辅修细胞生物学专业
生物医学工程、材料科学与工程、生物学、药学
纳米生物医学，药物递送系统，纳米药物，肿瘤免疫治疗，mRNA疫苗，肿瘤干细胞和靶向治疗
在Nature Nanotechnology、Science Translational Medicine、Nature Communications、PNAS、Nano Letters、Angew Chem Int Ed、J Am Chem Soc、Advanced Materials、ACS Nano等杂志发表通讯作者研究论文200余篇，论文被引用20000余次，H-Index 77；入选科睿唯安“高被引科学家”和爱思唯尔中国高被引学者；申请发明专利40余件，授权22件；获国家自然科学奖二等奖、广东省科学技术奖一等奖、教育部自然科学奖一等奖等；主持国家重点研发计划、国家自然科学基金重点等研究项目。
代表性论文列表：
[1]Mingdong Liu#, Liangqi Huang#, Weinan Zhang#, Xiaochuan Wang, Yuanyuan Geng, Yuhao Zhang, Li Wang, Wenbin Zhang, Yun-Jiao Zhang, Shiyan Xiao*, Yan Bao*, Menghua Xiong*, Jun Wang* ,A Transistor-Like pH-Sensitive Nanodetergent for Selective Cancer Therapy, Nature Nanothchnology, 2022, 17, 541-551
[2]Mengwen Huang#, Songrong Wang#, Senbiao Chen#, Jilong Wang, Congfei Xu, Jing Liu, Zhexiong Lian*, Xiaojiao Du*, Jun Wang*, Pegylated Liposomal Mitoxantrone Modulates Tumor Immune Landscape to Boost PD-L1 Blockade Therapy, Nano Today, 2022, 44, 101500
[3]Cheng-Tao Jiang#, Kai-Ge Chen#, An Liu, Hua Huang, Ya-Nan Fan, Dong-Kun Zhao, Qian-Ni Ye, Hou-Bing Zhang, Cong-Fei Xu, Song Shen*, Meng-Hua Xiong, Jin-Zhi Du, Xian-Zhu Yang, Jun Wang*, Immunomodulating nano-adaptors potentiate antibody-based cancer immunotherapy, Nature Communications, (2021) 12:1359
[4] Yansong Dong, Yalan Tu, Kewei Wang, Congfei Xu, Youyong Yuan*, Jun Wang*, A General Strategy for Macrotheranostic Prodrug Activation: Synergy by Tumor Acidic Microenvironment and Bioorthogonal Chemistry. Angew. Chem., Int. Ed., 2020, 59, 7168-7172.
[5] Hong-Jun Li#, Jing Liu#, Ying-Li Luo, Sen-Biao Chen, Jin-Zhi Du*, Jun Wang*, Intratumor Performance and Therapeutic Efficacy of PAMAM Dendrimers Carried by Clustered Nanoparticles. Nano Lett., 2019, 19, 8947-8955.
[6] Hua Huang, Cheng-Tao Jiang, Song Shen*, An Liu, Yun-Jiu Gan, Qi-Song Tong, Sen-Biao Chen, Zhu-Xin Gao, Jin-Zhi Du, Jie Cao*, Jun Wang*, Nanoenabled Reversal of IDO1-Mediated Immunosuppression Synergizes with Immunogenic Chemotherapy for Improved Cancer Therapy. Nano Lett., 2019, 19, 5356-5365.
[7]Jin-Zhi Du*, Hong-Jun Li, Jun Wang*, Tumor-Acidity Cleavable Maleic Acid Amide (TACMAA): A Powerful Tool for Designing Smart Nanoparticles to Overcome Delivery Barriers in Cancer Nanomedicine. Acc. Chem. Res., 2018, 51, 2848-2856.
[8]Cong-Fei Xu#, Zi-Dong Lu#, Ying-Li Luo, Yang Liu, Zhi-Ting Cao, Song Shen, Hong-Jun Li, Jing Liu, Kai-Ge Chen, Zhi-Yao Chen, Xian-Zhu Yang, Zhen Gu, Jun Wang*, Targeting of NLRP3 Inflammasome with Gene Editing for the Amelioration of Inflammatory Diseases. Nat. Commun., 2018, 9, 4092.
[9]Hong-Jun Li#, Jin-Zhi Du#, Xiao-Jiao Du#, Cong-Fei Xu, Chun-Yang Sun, Hong-Xia Wang, Zhi-Ting Cao, Xian-Zhu Yang, Yan-Hua Zhu, Shu-Ming Nie*, Jun Wang*, Stimuli-responsive Clustered Nano.particlesfor Improved Tumor Penetration and Therapeutic Efficacy. PNAS, 2016, 113, 4164-4169.
[10]Yan-Dan Yao#, Tian-Meng Sun#, Song-Yin Huang, Shuang Dou, Ling Lin, Jia-Ning Chen, Jian-Bin Ruan, Cheng-Qiong Mao, Feng-Yan Yu, Mu-Sheng Zeng, Jian-Ye Zang, Qiang Liu, Feng-Xi Su, Peter Zhang, Judy Lieberman*, Jun Wang*, Erwei Song*, Targeted Delivery of PLK1-siRNA by ScFv Suppresses Her2+ Breast Cancer Growth and Metastasis, Science Translational Medicine, 2012, 4, 130ra48 (Highlighted by Nature Review Cancer)