教授

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基本信息
李 宁

学  位     博士

专业技术职务  教授

导师情况    硕导

系所       食品生物技术研究所

研究方向    生物催化与生物转化

联系电话    020-22236669

Email      lining@scut.edu.cn

通讯地址    广州市天河区华南理工大学13号楼409



个人简介

1996.9-2000.6  南昌大学食品科学与工程本科

2000.9-2003.6华南理工大学发酵工程硕士

2003.7-2005.8  白云山化学制药厂

2005.9-2008.6 华南理工大学生物化工博士

2008.7-2011.9华南理工大学食品科学与工程学院讲师

2013.2-2014.2南加州大学化学系访问学者

2011.9-至今华南理工大学食品科学与工程学院教授


科研项目

1)油溶性维生素C脂肪酸酯合成的研究,企事业单位委托技术开发项目

2)新型[胆碱][氨基酸]离子液体预处理对木质纤维素酶解反应的影响机理(2014ZG0045),中央高校基本科研业务费项目

3)含DES介质中β-糖苷酶催化二糖核苷合成的研究(2012J2200011),珠江科技新星专项

4)新型[胆碱][氨基酸]离子液体预处理水稻秸秆过程及其机理研究(y207k31001),广州能源所开放基金

5)微生物细胞催化桦木醇选择性氧化合成桦木酸的关键技术研究(2010B011000003),广东省科技计划项目

6)含深度共熔溶剂(DES)介质中β-葡萄糖苷酶催化核苷葡萄糖基化反应的研究(20906032),国家自然科学基金


学术论文

近3年发表的主要论文

1)Hou XD, Xu J,Li N, Zong MH. Effect of anion structures on cholinium ionic liquidspretreatment of rice straw and the subsequent enzymatic hydrolysis. Biotechnol.Bioeng., 2014, DOI:10.1002/bit.25335

2)An YX, Li N, Zong MH, Lou WY.Easily measurable pH as an indicator of aqueous cholinium ionic liquidpretreatment effectiveness of lignocellulose. RSC Adv., 2014, 4 (98): 55635-55639

3)Hu YD, Qin YZ,Li N, Zong MH. Highly efficient enzymatic synthesis of an ascorbyl unstaturatedfatty acid ester with ecofriendly biomass-derived 2-methyltetrahydrofuran asco-solvent. Biotechnol. Prog., 2014,30 (5): 1005-1011

4)Yan LQ, Li N, Zong MH. Firstenzymatic galactosylation of acyclic nucleoside drugs by β-galactosidase:Synthesis of water-soluble β-D-galactosidic prodrugs. Biotechnol. BioprocessEng., 2014, 19 (4): 586-591

5)Hou XD, Li N,Zong MH. Renewable bio ionic liquids-water mixtures-mediated selective removalof lignin from rice straw: Visualization of changes in composition and cellwall structure. Biotechnol. Bioeng., 2013,110 (7): 1895-1902

6)Hou XD, Li N,Zong MH. Significantly enhancing enzymatic hydrolysis of rice straw afterpretreatment using renewable ionic liquid-water mixtures. Bioresour. Technol., 2013, 136 469-474

7)Hou XD, Li N,Zong MH. Facile and simple pretreatment of sugar cane bagasse without sizereduction using renewable ionic liquids-water mixtures. ACS Sustainable Chem.Eng., 2013, 1 (5): 519-526

8)Hou XD, Liu QP,Smith TJ, Li N, Zong MH. Evaluation of toxicity and biodegradability ofcholinium amino acids ionic liquids. PloS one, 2013, 8 (3): e59145

9)Liu H, Lei XL,Li N, Zong MH. Highly regioselective synthesis of betulone from betulin bygrowing cultures of marine fungus Dothideomycetesp. HQ 316564. J. Mol. Catal. B: Enzym., 2013,88: 32-35

10)Gao WL, Li N,Zong MH. Enzymatic regioselective acylation of nucleosides in biomass-derived2-methyltetrahydrofuran: kinetic study and enzyme substrate recognition. J.Biotechnol., 2013, 164 (1): 91-96

11)Liu QP, Hou XD,Li N, Zong MH. Ionic liquids from renewable biomaterials: synthesis,characterization and application in the pretreatment of biomass. Green Chem., 2012, 14 (2): 304-307

12)Hou XD, SmithTJ, Li N, Zong MH. Novel renewable ionic liquids as highly effective solventsfor pretreatment of rice straw biomass by selective removal of lignin.Biotechnol. Bioeng., 2012, 109 (10):2484-2493

13)Gao WL, Liu H,Li N, Zong MH. Regioselective enzymatic undecylenoylation of 8-chloroadenosineand its analogs with biomass-based 2-methyltetrahydrofuran as solvent.Bioresour. Technol., 2012, 118 82-88

14)Ye M, Yan LQ,Li N, Zong MH. Facile and regioselective enzymatic 5'-galactosylation ofpyrimidine 2'-deoxynucleosides catalyzed by β-glycosidase from bovine liver. J.Mol. Catal. B: Enzym., 2012, 7935-40

15)Yang RL, Li N,Zong MH. Using ionic liquid cosolvents to improve enzymatic synthesis ofarylalkyl β-D-glucopyranosides. J. Mol. Catal. B: Enzym., 2012, 74 (1-2): 24-28

16)Yan LQ, Li N,Zong MH. First and facile enzymatic synthesis of β-fucosyl-containingdisaccharide nucleosides through β-galactosidase-catalyzed regioselectiveglycosylation. J. Biotechnol., 2012,164 (2): 371-375

17)Liu X, Wei W,Yuan Q, Zhang X, Li N, Du Y, Ma G, Yan C, Ma D. Apoferritin-CeO2 nano-trufflethat has excellent artificial redox enzyme activity. Chem. Commun., 2012, 48 (26): 3155-3157

18)Gao WL, Liu H,Li N, Zong MH. Regioselective enzymatic undecylenoylation of 8-chloroadenosineand its analogs with biomass-based 2-methyltetrahydrofuran as solvent.Bioresour. Technol., 2012, 118 82-88

Chen L, Li N, Zong MH. A Glucose-tolerantβ-glucosidase from Prunus domestica seeds: purification and characterization.Process Biochem., 2012, 47 (1):127-132


获奖

1)2009年广东省优秀博士学位论文奖

2)2010年全国优秀博士学位论文提名论文奖

3)2012年广州市珠江科技新星

4)2013年广东省自然科学二等奖(排名第4)