1. 教育经历

1999年09月-2003年07月，兰州大学，生命科学学院，理学学士学位；

2003年09月-2008年12月，中山大学，生命科学学院，博士学位

2. 工作经历

2009年04月-2011年05月，华南理工大学，生物科学与工程学院，博士后；

2011年06月-2012年05月，华南理工大学，化学与化工学院，博士后；

2013年06月至今，华南理工大学，食品科学与工程学院，副研究员。

1. 国家自然科学青年基金：盖子结构调控高温脂肪酶催化特性机制研究，21406076

2. 广东省自然科学基金：定向固定化脂肪酶分子设计及其活性调控机理研究，S2012040006965

3. 高等学校博士学科点专项科研基金(新教师类)：盖子区影响高温脂肪酶催化特性的机理研究， No.20130172120014

1. Lan, D., Qu, M., Yang, B., & Wang, Y. (2016). Enhancing production of lipase MAS1 from marine Streptomyces sp. strain in Pichia pastoris by chaperones co-expression. Electronic Journal of Biotechnology, 22, 62–67.

2. Lan, D., Popowicz, G. M., Pavlidis, I. V., Zhou, P., Bornscheuer, U. T., & Wang, Y. (2015). Conversion of a Mono- and Diacylglycerol Lipase into a Triacylglycerol Lipase by Protein Engineering. ChemBioChem, 16(10), 1431–1434.

3. Lan, D., Wang, Q., Popowicz, G. M., Yang, B., Tang, Q., & Wang, Y. (2015). The role of residues 103, 104, and 278 in the activity of SMG1 lipase from Malassezia globosa: A site-directed mutagenesis study. Journal of Microbiology and Biotechnology, 25(11), 1827–1834.

4. Lan, D., Wang, Q., Xu, J., Zhou, P., Yang, B., & Wang, Y. (2015). Residue Asn277 affects the stability and substrate specificity of the SMG1 lipase from Malassezia globosa. International Journal of Molecular Sciences, 16(4), 7273–7288

5. Yuan, D., Lan, D., Xin, R., Yang, B., & Wang, Y. (2016). Screening and characterization of a thermostable lipase from marine Streptomyces sp. strain W007. Biotechnology and Applied Biochemistry, 63(1), 41–50.

6. Guo, S., Xu, J., Pavlidis, I. V., Lan, D., Bornscheuer, U. T., Liu, J., & Wang, Y. (2015). Structure of product-bound SMG1 lipase: Active site gating implications. FEBS Journal, 282(23), 4538–4547.

7. Wang, X., Xu, H., Lan, D., Yang, B., & Wang, Y. (2015). Hydrolysis of lysophosphatidylcholines by a lipase from Malassezia globosa. European Journal of Lipid Science and Technology, 117(10), 1655–1658

8. Xu, H., Lan, D. M., Yang, B., & Wang, Y. H. (2015). Biochemical properties and structure analysis of a DAG-like lipase from Malassezia globosa. International Journal of Molecular Sciences, 16(3), 4865–4879

9. Gao, C., Lan, D., Liu, L., Zhang, H., Yang, B., & Wang, Y. (2014). Site-directed mutagenesis studies of the aromatic residues at the active site of a lipase from Malassezia globosa. Biochimie, 102(1), 29–36

10.Qin, X. L., Huang, H. H., Lan, D. M., Wang, Y. H., & Yang, B. (2014). Typoselectivity of crude geobacillus sp. T1 lipase fused with a cellulose-binding domain and its use in the synthesis of structured lipids. Journal of the American Oil Chemists’ Society, 91(1), 55–62.

11.Qin, X. L., Lan, D. M., Zhong, J. F., Liu, L., Wang, Y. H., & Yang, B. (2014). Fatty acid specificity of T1 lipase and its potential in acylglycerol synthesis. Journal of the Science of Food and Agriculture, 94(8), 1614–1621.

12.Qin, X.-L., Zhong, J.-F., Wang, Y. H., Yang, B., Lan, D.-M., & Wang, F.-H. (2014). 1,3-Dioleoyl-2-palmitoylglycerol-rich human milk fat substitutes: Production, purification, characterization and modeling of the formulation. European Journal of Lipid Science and Technology, 116(3), 282–290.

13.Wang, W., Xu, Y., Qin, X., Lan, D., Yang, B., & Wang, Y. (2014). Immobilization of lipase SMG1 and its application in synthesis of partial glycerides. European Journal of Lipid Science and Technology, 116(8), 1063–1069.

14.Yuan, D., Lan, D., Xin, R., Yang, B., & Wang, Y. (2014). Biochemical properties of a new cold-active mono- and diacylglycerol lipase from marine member Janibacter sp. strain HTCC2649. International Journal of Molecular Sciences, 15(6), 10554–10566.

15.Liu, L., Lan, D., Wang, Q., Gao, C., Li, Z., Yang, B., & Wang, Y. (2013). A “bridge-like” structure responsible for the substrate selectivity of mono- and diacylglycerol lipase from Aspergillus oryzae. Journal of Molecular Catalysis B: Enzymatic, 97, 144–149.

酶工程关键技术研究与产业化，2015，广东省科学技术进步奖二等奖，排名5