Study

OFFICE
Room 603, Building No.2, Science and Technology Park (Wu Shan campus)
wangh@scut.edu.cn
WEBSITE/LAB
https://www2.scut.edu.cn/SESM/2022/0916/c33012a480964/page.htm
Dr. Hui Wang is currently an Associate Professor at the School of Emergent Soft Matter, South China University of Technology (SCUT). He obtained his Ph.D. in Life Sciences from East China Normal University (2011–2014) and a Master’s degree in Chemistry from the University of Science and Technology of China (2008-2011). His research focuses on polymer-based drug delivery systems, nanomaterial design, and gene/protein therapy applications. Prior to joining SCUT in 2018, Dr. Wang served as a Full-time Associate Professor at East China Normal University (2017–2018) and completed postdoctoral training at Changzheng Hospital, The Second Military Medical University (2014–2017). He has published over 25 peer-reviewed papers in high-impact journals such as Advanced Materials, Journal of the American Chemical Society, Nano Letters, and Angewandte Chemie.
Dr. Wang’s research focus is on the research focus is on the design of multi-dimensional polymers for intracellular protein/gene delivery and development of nano-structural devices (e.g., dendrimers, cationic polymers) for targeted therapy in cancer and neurological diseases.
2015
China Postdoctoral Science Foundation Fellowship (No. 57)
2016-2018
National Natural Science Foundation of China, (No. 8160070270)
2021-2023
Guangzhou Basic Research Program (No. 202102020823)
2022-2024
Principal Investigator for Guangdong Provincial Natural Science Foundation (No. 2022A1515011745).
2022-2026
Key Contributor to National Natural Science Foundation of China Key Program (No. B5215450).
Chen L, Wang H*, Cheng Y*. An erucin-anchored polymer with excellent amyloidosis inhibition and direct cell membrane penetration ability for intracellular protein delivery, Chinese Chemical Letters, 2025, https://doi.org/10.1016/j.cclet.2025.111172
Wang H*, Cheng Y*. Polymers for mRNA Delivery. WIREs Nanomed Nanobiotechnol, 2025, 17, e70002.
Liang M, Wang Q, Zhang S, Lan Q, Wang R, Tan E, Zhou L, Wang C*, Wang H*, Cheng Y*. Polypyridiniums with Inherent Autophagy-Inducing Activity for Atherosclerosis Treatment by Intracellularly Co-Delivering Two Antioxidant Enzymes. Advanced Materials, 2024, 36, e2409015.
Chen L, Hu Y, Cheng Y*, Wang H*. A Hydroxyquinoline Polymer with Excellent Amyloidosis Inhibition and Protein Delivery Ability to Combat Amyloid-β-Mediated Neurotoxicity. Nano Letters, 2024, 24, 12882-12890.
Gao P, Chen Y, He Q, Liu Q, Tan E, Yu Z*, Wang H*. Highly efficient adoptive cell therapy of metastatic triple negative breast cancer with bioactive covalent organic framework-engineered macrophages. Chinese Chemical Letters, 2024, doi: https://doi.org/10.1016/j.cclet.2024.110585.
Wang R, Li Y, Gao P, Lv J, Cheng Y*, Wang H*. Piperazine-modified dendrimer achieves efficient intracellular protein delivery via caveolar endocytosis bypassing the endo-lysosomal pathway, Acta Biomaterialia, 2023, 158, 725-733.
Liang M, Cheng Y*, Wang H*. A Cu+/Thiourea Dendrimer Achieves Excellent Cytosolic Protein Delivery via Enhanced Cell Uptake and Endosome Escape, Chemistry - A European Journal, 2023, 29, e202300131.
Zhang Z, Gao X, Li Y, Lv J, Wang H*, Cheng Y*. Catechol-Based Polymers with High Efficacy in Cytosolic Protein Delivery, CCS Chemistry, 2023, 5, 1411–1421.
Gao P, Wang H*, Cheng Y*. Strategies for efficient photothermal therapy at mild temperatures: Progresses and challenges, Chinese Chemical Letters, 2022, 33, 575-586.
Wang H, Zhang S, Lv J, Cheng Y. Design of polymers for siRNA delivery: Recent progress and challenges. View, 2021, 2,20200026.
Lv J, Wang C, Li H, Li Zh, Fan Q, Zhang Y, Li Y, Wang H*, Cheng Y*. Bifunctional and Bioreducible Dendrimer Bearing a Fluoroalkyl Tail for Efficient Protein Delivery Both In Vitro and In Vivo. Nano Letters, 2020, 20, 8600-8607.
Wang H, Wang C, Zou Y, Hu J, Li Y, Cheng Y. Natural polyphenols in drug delivery systems: Current status and future challenges. Giant, 2020, 3, 100022.
Cheng X, Li M, Wang H*, Cheng Y*. All-small-molecule dynamic covalent gels with antibacterial activity by boronate-tannic acid gelation. Chinese Chemical Letters, 2020, 31, 869-874.
Wang H, Cheng Y. All-small-molecule dynamic covalent hydrogels with multistimuli responsiveness. Materials Chemistry Frontiers, 2019, 3, 472-475.
Wang H, Miao W, Wang F, Cheng Y. A Self-Assembled Coumarin-Anchored Dendrimer for Efficient Gene Delivery and Light-Responsive Drug Delivery. Biomacromolecules, 2018, 19, 2194-2201.
Undergraduate courses:
Biochemistry
Graduate courses:
The Chemistry in Life