Name:

Lijuan Zhang

Introduction:

Tel/ Fax: 86-20-87112046
E-mail: celjzh@scut.edu.cn.

Education Backgroud:
2002-Ph. D., (Env. Eng.), South China University of Technology, China.
1989-M. Sc., (Appl. Chem.), South China University of Technology, China.
1986-B. Sc., (Appl. Chem.), South China University of Technology, China.

Research Areas:
Chemical product engineering focused on:
 Relationship between structures and properties of heterogeneous complex products
 Molecular simulation and micro-dimension drug delivery control
 Functional polymer material for drug delivery

Current research projects：
 “Multiscale structure-property relationships of pH-sensitive polymer brush and drug-loaded micelle delivery system”. National Natural Science Foundation of China (NSFC)
 “Mesoscale correlation mechanism and control for the performance and structure of self-assembled microparticle chemicals”. National Natural Science Foundation of China (NSFC)
 “Fundamental study on structure-property relationship and processing technology of functional chemical products”. The Team Project of Natural Science Foundation of Guangdong Province
 “The quantitative structure-performance relationship of drug-loaded polymeric micelles”. Specialized Research Fund for the Doctoral Program of Higher Education of China

Recent Publications:
 Wen Sheng Wu, Can Yang Zhang, Wen Jing Lin, Quan Chen, Xin Dong Guo, Yu Qian, and Li Juan Zhang*. Quantitative Structure-Property Relationship (QSPR) Modeling of Drug-Loaded Polymeric Micelle via Genetic Function Approximation, PLOS ONE, 2015, 10(3): e0119575.
 Shu Yu Nie, Wen Jing Lin, Na Yao, Xin Dong Guo*, Li Juan Zhang*. Drug release from pH-sensitive micelles with Different Drug Distributions: Insight from coarse-grained simulations, ACS Applied Materials & Interfaces. 2014, 6: 17668-17678
 Wen Jing Li, Shu Yu Ni, Quan Chen, Yu Qian, Xiufang Wen, Li Juan Zhang*. Structure-properties relationships of pH-responsive (PCL)2(PDEA-b-PPEGMA)2 micelles: Experiments and dissipative particle dynamics simulation, AIChE. J, 2014, 60(10), 3634-3646
 Can Yang Zhang, Di Xiong, Yao Sun, Bin Zhao, Wen Jing Lin, Li Juan Zhang*. Self-assembled micelles based on pH-sensitive PAE-g-MPEG-Cholesterol block copolymer for anticancer drug delivery, International Journal of Nanomedicine. 2014, 9: 4923-4933
 Wen Jing Lin, Shu Yu Nie, You Qiang Yang, Qi Zhong, Cheng Zhi Cai, Ju Fang Wang, Li Juan Zhang*. Amphiphilic miktoarm star copolymer (PCL)3-(PDEAEMA-b-PPEGMA)3 as pH-sensitive micelles in the delivery of anticancer drug，Journal of Materials Chemistry B, 2014, 2 (25): 4008-4020
 Wen Jing Lin, Shu Yu Nie, Di Xiong, Xin Dong Guo, Ju Fang Wang, Li Juan Zhang*. pH-Responsive Micelles Based on (PCL)2(PDEA-b-PPEGMA)2 miktoarm polymer: controlled Synthesis, characterization and application as anticancer drug carrier, Nanoscale Research Letters, 2014, 9(1): 243-254  
 Shu Yu Nie, Yao Sun, Wen Jing Lin, Wen Sheng Wu, Xin Dong Guo, Yu Qian and Li Juan Zhang*. Dissipative particle dynamics simulation of doxorubicin loaded/pH-induced released micelles assembled from four-arm star triblock polymers 4AS-PCL-b-PDEAEMA-b-PPEGMA. Journal of Physical Chemistry B, 2013, 117, 13688-13697
 You Qiang Yang, Bin Zhao, Zhen Dong Li, Wen Jing Lin, Can Yang Zhang, Xin Dong Guo, Ju Fang Wang, Li Juan Zhang,* pH-sensitive micelles self-assembled from multiarm star triblock copolymers 4/6AS-PCL-b-PDEAEMA-b-PPEGMA for controlled anticancer drug delivery, Acta Biomaterialia, 2013, 9: 7679–7690
 Xin Dong Guo*, Yu Qian, Can Yang Zhang, Shu Yu Nie, and Li Juan Zhang*. Can Drug Molecules Diffuse into the Core of Micelles? Soft Matter, 2012, 8(39): 9989-9995
 Can Yang Zhang, You Qiang Yang, Tu Xiong Huang, Zhao Bin, Xin Dong Guo, Ju Fang Wang, Li Juan Zhang*. Self-assembled pH-responsive MPEG-b-(PLA-co-PAE) block copolymer micelles for anticancer drug delivery. Biomaterials, 2012, 33: 6273-6283
 You Qiang Yang, Wen Jing Lin, Bin Zhao, Xiu Fang Wen, Xin Dong Guo, Li Juan Zhang*. Synthesis and Physicochemical Characterization of Amphiphilic Triblock Copolymer Brush Containing pH-sensitive Linkage for Oral Drug Delivery, Langmuir, 2012, 28: 8251-8259