Tissue Engineering and Medical Devices Research Center

The Tissue Engineering and Medical Devices Research Center focuses on addressing critical scientific and technological challenges in tissue engineering by investigating regulatory strategies and mechanisms for tissue/organ development and regeneration. The center develops biologically adaptive materials for tissue/organ repair and regeneration, ultimately creating high-performance medical devices. With a comprehensive research framework spanning fundamental studies to clinical translation, the center aims to produce original, high-impact scientific achievements while accelerating technology transfer to benefit public health.  

The center's team includes Yingjun Wang (Fellow of Chinese Academy of Engineering), Liming Bian, Xiaoling Fu, Peng Shi, Yaoli Zhang, Pengchao Zhao, Xiayi Xu, Xuetao Shi, and Jinjin Ma. Among them are 1 CAE Fellow, 1 Changjiang(Yangtze River) Scholar, and 4 recipients of national-level young talent programs.  

In research and commercialization, the center has undertaken national key R&D programs and NSFC projects, yielding significant academic outputs, technical patents, and publications in leading bio-materials and tissue engineering journals. Multiple innovations have obtained national medical device certifications, generating substantial social and economic benefits.  

Addressing fundamental challenges in bio-materials and tissue engineering, CAE Academician Yingjun Wang, the center's chief scientist, pioneered the internationally recognized Biological Adaptation concept. This framework investigates relationships between material composition, hierarchical structures, surface properties, degradation/mechanical characteristics, and cellular behaviors to guide functional biomaterial design. Under this guidance, the team has resolved key technical challenges including controllable porous structures, bone-like surface energetics, osteochondral integration, and antibacterial component optimization—developing world-leading biomaterials for clinical applications.