Lingxiang JIANG

Biography

  • Lingxiang Jiang is a recipient of the National Science Fund for Excellent Young Scholars (2021) and currently serves as a Professor at the School of Emerging Soft Matter, South China University of Technology. He received his bachelor's degree (2007) and Ph.D. (2012) from Peking University, followed by postdoctoral research at the University of Illinois at Urbana-Champaign. In 2016, he returned to China to establish an independent research group at Jinan University, and in 2020, he joined SCUT. His research focuses on biomimetic self-assembly and dynamic behaviors. He has constructed a variety of biomimetic subcellular structures, identified key structural motifs, and elucidated underlying assembly mechanisms.

Research Interests

  • His work explores the functional roles of biomimetic systems at the cellular scale and has achieved breakthroughs in their macroscopic applications. Specifically, his group designs, synthesizes, and constructs biomimetic systems by simplifying subcellular structures into minimal model systems. The results demonstrate that seemingly complex architectures can arise from simple small molecules governed by fundamental physicochemical principles.

  • 1.Constructed a variety of biomimetic subcellular structures, identified key structural motifs, and elucidated fundamental assembly mechanisms. These systems were used to explore functional roles at the cellular scale, leading to breakthroughs in macroscopic applications.

  • 2.Developed condensate droplets composed of carbon–fluorine molecules, which provide protective microenvironments for enzymes and biomacromolecules, enabling them to retain bioactivity under extreme conditions.

  • 3.Advanced a suite of optical imaging and manipulation techniques, enabling targeted investigation of self-assembly and dynamic behaviors across millisecond-to-second timescales and nanometer-to-micrometer spatial resolution.

Awards & Honors

2019
Selected as an Outstanding Young Researcher by Current Opinion in Colloid & Interface Science

2020
Named an Emerging Investigator by Chemical Communications


Recipient of the 5th “Dongfang Jiaohua” Colloid and Interface Chemistry Young Scholar Award

Selected Publications

  • Da Tang, Jun Zhu, Hao Wang, Nannan Chen, Hui Wang, Yongqi Huang, Lingxiang Jiang* Universal membranization of synthetic coacervates and biomolecular condensates towards ultrastability and spontaneous emulsification, Nature Chemistry 2025, https://doi.org/10.1038/s41557-025-01800-4

  • Hao Wang, Hui Zhuang, Wenjing Tang, Jun Zhu, Wei Zhu*, Lingxiang Jiang* Coacervate-pore complexes for selective molecular transport and dynamic reconfiguration, Nature Communications 2024, 15, 10069

  • Xixi Chen,# Tianli Wu,# Danmin Huang,# Jiajia Zhou, Fengxiang Zhou, Mei Tu, Yao Zhang, Baojun Li, Yuchao Li,* Lingxiang Jiang* Optothermally Programmable Liquids with Spatiotemporal Precision and Functional Complexity, Advanced Materials 2022, 2205563

  • Qingqiao Xie, Yuandi Zhuang, Gaojun Ye, Tiankuo Wang, Yi Cao, and Lingxiang Jiang* Astral hydrogels mimic tissue mechanics by aster-aster interpenetration, Nature Communications 2021, 12, 4277.

  • Qingqiao Xie, Xixi Chen, Tianli Wu, Tiankuo Wang, Yi Cao, Steve Granick, Yuchao Li,* and Lingxiang Jiang* Synthetic asters as elastic, radial skeletons, Nature Communications 2019, 10, 4954.

  • Shenyu Yang, Yan Yun, Jianbin Huang, Andrei V. Petukhov, Loes M. J. Kroon-Batenburg, Markus Drechsler, Chengcheng Zhou, Mei Tu, Steve Granick, and Lingxiang Jiang* Giant Capsids from Lattice Self-Assembly of Cyclodextrin Complexes, Nature Communications 2017, 8, 15856.

  • Lingxiang Jiang,* Qingqiao Xie, Boyece Tsang, and Steve Granick,* Single-crosslink microscopy in a biopolymer network dissects local elasticity from molecular fluctuations, Nature Communications 2019, 10, 3314.

  • Lingxiang Jiang,* Shenyu Yang, Boyce Tsang, Mei Tu, and Steve Granick,* Vector assembly of colloids on monolayer substrates, Nature Communications 2017, 8, 15778.

Teaching

Undergraduate courses:

Colloidal and interface chemistry

Analytical Chemistry