关于举行日本大阪大学井上佳久教授学术报告会的通知 发布者:魏巍   发布时间:2019-12-09   浏览次数:223

报告题目:1. Supramolecular Photochirogeneses

                    2. Biomolecular Photochirogeneses

    人:井上佳久(Yoshihisa Inoue)教授(日本大阪大学)

报告时间:1. 1213日上午930 

                    2. 1216日下午1430

报告地点:逸夫工程馆四楼会议室 

 

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化学与化工学院

2019129

报告人简介:

      井上佳久,日本大阪大学教授,是现代光化学和超分子化学的先驱和领导者之一,在分子手性和超分子熵控制光反应方面做出了重大贡献。首次通过手性光化学的方法,以分子、超分子和生物分子等多种体系为媒介得到了最高光学收益率的手性化合物;首次发现能与天然生物素对媲美的人工合成主客体体系,这种至今为止最强的分子胶水的形成完全超越了被广泛认可的焓熵补偿效应,从而发展了分子识别的新理论。在Nature, Chem. Rev., J. Am. Chem. Soc., Angew. Chem. Int. Ed.,等期刊发表论文500余篇,出版了40本专著,综述近百篇;申请专利42项(其中国际专利11项)。曾主持日本科学振兴会(JST)项目3项,日本文部省(MEXT)项目3项;2007年获瑞士CUSOLectureship Award奖,2009年获日本光化学协会的JPA Lectureship Award奖,2011年获德国洪堡基金会的Humboldt Research Award奖和德国HonoraryHans Fischer Senior Fellow (汉斯菲舍尔名誉高级研究员)称号。现为亚太环糊精联盟副主席,日本光化学家协会委员、日本环糊精协会委员、分子手性协会委员、《超分子化学杂志》顾问委员会委员、日本文部省特别研究基金补助金选拔委员会主席。

 

报告摘要:

Supra- and Bio-molecular Photochirogeneses

 

Yoshihisa Inoue

Osaka University

inoue@chem.eng.osaka-u.ac.jp

 

Chiral photochemistry or photochirogenesis is one of the most intriguing, yet challenging topics in current chemistry, as a unique methodology for creating molecular chirality through the electronically excited-state reactions, which is alternative or complementary to the conventional catalytic and enzymatic asymmetric syntheses that already met a great success in the last decades.1-6 Of various strategies developed so far, chiral supramolecular and biomolecular approaches are of particular interest and advantages, where prochiral substrates are confined, pre-organized, pre-oriented, and even accumulated in chiral nanospace before and during the photochemical transformation (see below).

After a brief introduction to the history of photochirogenesis, the recent results of our researches on supramolecular9 and biomolecular10 photochirogenesis will be discussed in successive two lectures (part 1 & 2) by using some selected examples to demonstrate that the photochirogenesis is not only an attractive alternative to the thermal counterpart but also a unique methodology for obtaining chiral compounds through the electronically excited state in the chiral low-entropy environment.

 

References

  1. Inoue, Y. Chem. Rev.1992, 92, 741.

  2. Inoue, Y.; Ramamurthy, V. Chiral Photochemistry; Dekker: New York, 2004.

  3. Ramamurthy, V.; Inoue, Y. Supramolecular Photochemistry; Wiley: Hoboken, 2011.

  4. Yang, C.; Inoue, Y. Chem. Soc. Rev.2014, 43, 4123.

  5. Ramamurthy, V.; Gupta, S. Chem. Soc. Rev.2015, 44, 119.

  6. Poplata, S.; Tröster, A.; Zou, Y.-Q.; Bach, T. Chem. Rev.2016, 116, 9748.

  7. Ramamurthy, V.; Sivaguru, N. Chem. Rev. 2016, 116, 9914.

  8. Yang, C.; Inoue, Y. Nature2018, 564, 197.

  9. (a) Inoue, Y.; Dong, F.; Yamamoto, K.; Tong, L.-H.; Tsuneishi, H.; Hakushi, T.; Tai, A. J. Am. Chem. Soc.1995, 117, 11033. (b) Yao, J.; Yan, Z.; Ji, J.; Wu, W.; Yang, C.; Nishijima, M.; Fukuhara, G.; Mori, T.; Inoue, Y. J. Am. Chem. Soc.2014, 136, 6916. (c) Kawanami, Y.; Katsumata, S.; Nishijima, M.; Fukuhara, G.; Yang, C.; Nakamura, A.; Mori, T.; Inoue, Y. J. Am. Chem. Soc.2016, 138, 12187. (d) Ji, J.; Wu, W.; Liang, W.; Cheng, G.; Matsushita, R.; Yan, Z.; Wei, X.; Rao, M.; Yuan, D.; Fukuhara, G.; Mori, T.; Inoue, Y.; Yang, C. J. Am. Chem. Soc.2019, 141,9225.

  10. (a) Wada, T.; Nishijima, M.; Fujisawa, T.; Sugahara, N.; Mori, T.; Nakamura, A.; Inoue, Y. J. Am. Chem. Soc.2003, 125, 7492. (b) Fuentealba, D.; Kato, H.; Nishijima, M.; Fukuhara, G.; Mori, T.; Inoue, Y.; Bohne, C. J. Am. Chem. Soc.2013, 135, 203. (c) Nishijima, M.; Goto, M.; Fujikawa, M.; Yang, C.; Mori, T.; Wada, T.; Inoue, Y. Chem. Commun.2014,50, 14082. (d) Nishijima, M.; Pace, T.C.S.; Bohne, C.; Mori, M.; Inoue, Y.; Wada T. J. Photochem. Photobiol., A: Chem., 2016, 331, 89.