Topic: Development of biomimetic scaffolds for bone regeneration

Speaker: WEI Mei, University of Connecticut, American

Time: 10:00 a.m., June 21, 2016

Venue: Conference Room 410, Building B12, SCUT South Campus

Abstract:

The newly emerged field of tissue engineering has provided a major potential to repair and regenerate bone using a combination of scaffold matrix and bone progenitor cells. Despite of the early success in bone tissue engineering, many currently existing bone scaffolds still suffer from poor osteoconductivity and inappropriate degradation rate. Thus, there is a pressing need to produce a bone tissue engineering scaffold which can well support progenitor cell activities and have its degradation rate matched that of new bone ingrowth to enhance new bone formation. Currently, the Wei research group at the University of Connecticut has developed a novel lamellar biomimetic bone scaffold with excellent osteoconductivitiy and appropriate degradation rate. More importantly, the scaffold significantly enhances bone formation. In the present talk, the scaffold fabrication technique, microstructure, in vivo performance, and in situ cell-scaffold interaction in living animal will be discussed.