学历：博士
职称：副教授
民族：汉族
研究方向：酶工程
Email：birxyang@scut.edu.cn
2003.5—2007.2德国斯图加特大学物理化学所物理化学博士
2000.9—2003.3中国科学院北京化学所分析化学硕士
1992.9—1996.6重庆大学化工学院精细化工本科
工作经历
2014.10 — 至今华南理工大学生物科学与工程学院副教授
2008.8—2014.9美国宾州州立大学化学系博士后
2006.5—2007.2德国斯图加特大学物理化学研究所教学助理
1996.7—2000.5中国重庆三峡油漆股份有限公司技术员
研究兴趣
酶结构和运动的表征及酶分子改造
近五年发表的主要科研论文：
[1]Ibrahim M Moustafa, Victoria S Korneeva, Jamie J Arnold, Eric D Smidansky,Laura L Marcotte, David W Gohara, XiaorongYang, Maria A Sánchez-Farrán, David Filman, Janna KMaranas, David D Boehr, James M Hogle, Coray M Colina, Craig E Cameron,Structural Dynamics as a Contributor to Error-prone Replication by aRNA-dependent RNA Polymerase, J. Biol. Chem. 2014, 289,36229-36248.
[2]DavidD Boehr, Xinran Liu, Xiaorong Yang,Targeting structural dynamics of the RNA-dependent RNA polymerase foranti-viral strategies. Curr. Opin. Virol. 2014, 9, 194-200.
[3] XinranLiu, Xiaorong Yang (co-first author),Cheri A. Lee, Ibrahim M. Moustafa, Eric D. Smidansky, David Lum, Jamie J.Arnold, Craig E. Cameron, David D. Boehr, Vaccine-derived mutation in motif Dof poliovirus RNA-dependent RNA polymerase lowers nucleotide incorporationfidelity, J. Biol. Chem. 2013, 288, 32753-65.
[4] YanM Chan, Xiaorong Yang, David DBoehr, The Role of Phosphatidylinositol Phosphates (PIPs) in PoliovirusReplication Complexes Trafficking to Viral Replication Organelles, Biophys. J. 2013, 104(2), Supplement:1, Pages:98A-98A.
[5] IbrahimM Moustafa, Victoria S Korneeva, Jamie J Arnold, Eric D Smidansky, Laura LMarcotte, Xiaorong Yang, Janna KMaranas, David D Boehr, James M Hogle, Coray M Colina, Craig E Cameron,Nanosecond-Timescale Dynamics of the Viral RNA-Dependent RNA Polymerase as aDeterminant of Incorporation Fidelity, Biophys. J. 2013, 104(2), Supplement:1,Pages:213A-213A.
[6] Xiaorong Yang, Eric D. Smidansky,Kenneth R. Maksimchuk, David Lum, Jesse L. Welch, Jamie J. Arnold, Craig E.Cameron, David D. Boehr, Motif D of viral RNA-dependent RNA polymerasesdetermines efficiency and fidelity of nucleotide addition, Structure, 2012, 20,1519-1527.
[7] Xiaorong Yang, Klaus Müller, The guest ordering anddynamics in urea inclusion compounds studied by solid state 1H and 13C MAS NMRspectroscopy, J. Mol. Struct. 2011, 1006, 113-120.
[8] Xiaorong Yang, Klaus Müller, The structural anddynamic properties of 1-bromodecane in urea inclusion compounds investigated bysolid state 1H, 13C and 2H NMR spectroscopy, Magn. Reson. Chem. 2011, 49,514-522.
[9] Xiaorong Yang, Jesse L. Welch, Jamie J.Arnold, David D. Boehr, Long-range interaction networks in the function andfidelity of poliovirus RNA-dependent RNA polymerase studied by nuclear magneticresonance, Biochemistry, 2010, 49, 9361-9371.
