招生专业:医药生物学,药学;硕士
研究方向:药物分析、药物代谢
Email:tingzhou@scut.edu.cn
教育经历
2002-2006 中国药科大学国家生命科学与技术人才培养基地班学士
2006-2008 中国药科大学硕士
2008-2011 中山大学博士
工作经历
2012.03-2014.10华南理工大学生物科学与工程学院讲师
2014.11-至今 华南理工大学生物科学与工程学院副教授 (破格)
教学科研情况
研究兴趣包括手性药物分析、手性药物立体选择性代谢及手性转化研究、代谢组学、脂质组学、生物样品前处理-色谱质谱联用系统的研发等。讲授本科生课程《药物分析》、《生物医药与健康》,研究生课程《体内药物分析》、《药物分析方法》、《药物色谱质谱分析原理》等。
主持国家自然科学基金面上项目一项,国家自然科学基金青年基金项目一项,广东省自然科学基金一项,广州市珠江科技新星项目一项,中央高校面上项目一项,中央高校博士启动项目一项,并指导本科生SRP项目及创新基金项目。参与国家973计划项目、国家自然科学基金项目以及省市项目多项。
以第一作者和通讯作者发表SCI论文15篇,发明专利2项。担任Journal of Chromatography A, Analytical and Bioanalytical Chemistry, Journal of Separation Science, Phytochemical Analysis等多个期刊的审稿人,并担任期刊Journal of Pharmaceutical Analysis的青年编委。
获奖情况
2018年 广州市珠江科技新星
(1)主要的研究项目:
1、国家自然科学基金面上项目:柱前稀释固相萃取-超临界流体色谱质谱在线联用技术及其在手性药物分析中的应用,2018.01-2020.12(主持)
2、国家自然科学基金青年基金项目:微波辅助衍生-UPLC-MS/MS联用技术及在手性药物分析中的应用,2015.01-2017.12(主持)
3、广东省自然科学基金博士启动项目:在线手性衍生-液质联用及在β2-激动剂分析中的应用,2013.10-2015.10(主持)
4、广州市珠江科技新星专项:基于固相萃取-超临界流体色谱-质谱联用技术的脑卒中脂质组学研究,2018.04-2021.03(主持)
5、中央高校基本科研业务费面上项目:β2-激动剂的手性分析及手性转化研究,2015.01-2016.12(主持)
6、中央高校基本科研业务费博士启动项目:β2-受体激动剂代谢的立体选择性研究,2013.01-2014.12(主持)
(2)代表性论文:
1. Yang Yang, Qisheng Zhong,Canlong Mo, Hao Zhang,Ting Zhou*(通讯作者), Wen Tan. Determination of endogenous inflammation-related lipid mediators in ischemic stroke rats using background subtracting calibration curves by liquid chromatography-tandem mass spectrometry. Analytical and Bioanalytical Chemistry, 2017, 409(28), 6537-6547.
2. Zhou, Ting, Zeng, Jing, Zhao, Ting, Zhong, Qisheng, Yang, Yang, Tan, Wen, Enantioselective analysis of bambuterol in human plasma using microwave-assisted chiral derivatization coupled with ultra high performance liquid chromatography and tandem mass spectrometry. Journal of Separation Science, 2017, 40(13), 2779-2790.
3. Qisheng Zhong, Lingling Shen, Jiaqi Liu, Dianbao Yu, Simin Li, Jinting Yao, Song Zhan, Taohong Huang, Shinichi Kawano, Yuki Hashi,Zhaofeng Liu,Ting Zhou*(通讯作者). Pre-column dilution large volume injection ultra-high performance liquid chromatography-tandem mass spectrometry for the analysis of multi-class pesticides in cabbages. Journal of Chromatography A, 2016, 1442, 53-61.
4. Qisheng Zhong, Lingling Shen, Jiaqi Liu, Dianbao Yu, Simin Li, Zhiru Li, Jinting Yao, Taohong Huang, Shin-ichi Kawano, Yuki Hashi, Ting Zhou*(通讯作者). Automatic on-line solid-phase extraction with ultra high performance liquid chromatography and tandem mass spectrometry for the determination of ten antipsychotics in human plasma. Journal of Separation Science, 2016, 39(11), 2129-2137.
5. T. Zhou, D. Zeng, T. Zhao, Y. Yang, S. Liu, J. Wu, L. Xu, W. Tan, In vivo metabolism study of (R)-bambuterol in humans using ultra high performance liquid chromatography with tandem mass spectrometry.Journal of Separation Science, 2016, 39(15), 2896-2906.
6. Ting Zhou, Jing Zeng, Shan Liu, et al. Study on the determination and chiral inversion of R-salbutamol in human plasma and urine by liquid chromatography-tandem mass spectrometry. Journal of chromatography B, 2015, 1002, 218-227.
7. Ting Zhou, Shan Liu, Ting Zhao, et al.Chiral analysis of bambuterol, its intermediate and active drug in human plasma by liquid chromatography- tandem mass spectrometry: application to a pharmacokinetic study. Journal of chromatography B, 2015, 997: 38-44.
8. Qisheng Zhong, Xiongxiong Qiu, Caiyong Lin, Lingling Shen, Yin Huo, Song Zhan,Jinting Yao, Taohong Huang, Shinichi Kawano, Yuki Hashi,Langtao Xiao,Ting Zhou*(通讯作者). An automatic versatile system integrating solid-phase extraction with ultra-high performance liquid chromatography–tandem mass spectrometry using a dual-dilution strategy for direct analysis of auxins in plant extracts. Journal of Chromatography A, 2014, 1359(23): 131-139.
9. Ting Zhou, Qing Cheng, Chengjuan Zou, Ting Zhao, Shan Liu, Marco Pistolozzi, Evina Tan, Ling Xu, Wen Tan.Simultaneous determination of bambuterol and its two major metabolites in human plasma by hydrophilic interaction ultra-performance liquid chromatography-tandem mass spectrometry. Journal of chromatography B, 2014, 967: 225-234.
10. Ting Zhou, Ting Zhao, Qing Cheng, Shan Liu, Ling Xu, Wen Tan. A sensitive LC-MS/MS method for simultaneous determination of R-bambuterol and its active metabolite R-terbutaline in human plasma and urine with application to a clinical pharmacokinetic study. Biomedical chromatography, 2014, 28(7): 994-1002.
11. Ting Zhou, Xiao-Hua Xiao,Gong-Ke Li. Microwave Accelerated Selective Soxhlet Extraction for the Determination of Organophosphorus and Carbamate Pesticides in Ginseng with Gas Chromatography/Mass Spectrometry. Analytical Chemistry, 2012, 84(13): 5816-5822.
12. Ting Zhou, Xiao-Hua Xiao,Gong-Ke Li. Hybrid Field-Assisted Solid-Liquid-Solid Dispersive- Extraction for the Determination of Organochlorine Pesticides in Tobacco with Gas Chromatography. Analytical Chemistry, 2012, 84(1): 420-427.
13. Ting Zhou, Xiao-Hua Xiao, Gong-Ke Li, Zong-wei Cai. Study of polyethylene glycol as a green solvent in the microwave-assisted extraction of flavone and coumarin compounds from medicinal plants. Journal of Chromatography A, 2011, 1218(23): 3608-3615.
14. Ting Zhou, Xiao-Hua Xiao, Jia-Yue Wang, Jin-Ling Chen, Xian-Fang Xu, Zhi-Feng He, Gong-Ke Li. Evaluation of microwave-assisted extraction for aristolochic acid from Aristolochiae fructus by chromatographic analysis coupled with nephrotoxicity studies. Biomedical Chromatography, 2012, 26(2): 166-171.
15. Ting Zhou, Li Ding, Xiaomin Li, Fei Zhang, Qian Zhang, Bing Gong, Xiaofeng Guo. Determination of iguratimod in rat plasma by high performance liquid chromatography: method and application. Biomedical chromatography, 2008, 22(3): 260-264.
16. Tong X, Zhou T, Xiao XH, Li GK. A consecutive preparation method based upon accelerated solvent extraction and high-speed counter-current chromatography for isolation of aesculin from Cortex Fraxinus. Journal of separation science, 2012, 35(24):3609-3614.
17. 周婷, 王家玥, 肖小华, 李攻科. 天然产物样品前处理分离分析联用技术研究进展. 世界科学技术(中医药现代化), 2009(01): 147-152.
18. 周伟宏, 王燕玲, 周婷. 高效液相色谱法测定2-(4-甲氧基苯氧基)丙酸钠的含量. 中国食品添加剂, 2011(1): 237-240.
(3)专利
在线微波辅助手性衍生-液质联用系统及其应用. 申请号:201610329982.8
微波辅助索氏固相萃取联用装置、方法及应用. CN 102507297 B. 已授权