庆祝华南理工大学组建70周年暨有机光电学术讲座第五十二讲

2022-11-21 907

报 告 一:嵌入细胞膜的共轭齐聚电解质

报 告 人:周城 教授

报告时间:2022 年 11 月 25日 (周五)15:00 – 16:00

报告地点:北区科技园1号楼国重N308A报告厅

报告摘要:作为新一类的分子体系,部分共轭齐聚电解质(conjugated oligoelectrolyte, COE)具有一个疏水的、线性的共轭骨架核心,其分子两端由末端为极性基团的侧链修饰。从化学结构来看,这些COE分子的疏水基团和亲水基团的分布跟磷脂双分子层类似。因此,这些COE分子能够通过静电和疏水相互作用自发地嵌入到细胞膜中。通过对COE化学结构的调整,可以控制COE分子与细胞膜之间的相互作用,进而实现不同功能应用。例如,一些长链的COE分子的刚性共轭骨架能够通过疏水-疏水相互作用支撑磷脂双分子层的酯基部分,从而增强细胞膜的稳定性。相反,如果COE的分子长度小于磷脂双分子层的厚度(≈4 nm),嵌入细胞膜后的COE由于长度的不匹配将破坏细胞膜的稳定性,并被用来开发成抗菌或抗癌药物。另外,部分COE在水溶液不聚集,嵌入细胞膜后荧光强度显著增强,说明COE可作为优秀的细胞膜靶向的荧光探针。膜嵌入COE分子平台展现出广阔的应用前景,本报告将举例这类材料在外泌体检测、肿瘤生长跟踪、抗菌、稳定脂质膜、选择性荧光标记等方面的应用。

 

报 告 二:Basic introductions of TAS and charge generation in PSMA-based OSCs

报 告 人:陈振沣 博士

报告时间:2022 年 11 25日 (周五)16:00 – 17:00

报告地点:北区科技园1号楼国重N308A报告厅


报告摘要:This talk comprises of three sections: 1) reports on resetting up, maintenance and repairs of the instruments of ultrafast platform; 2) a basic introduction of TAS; and 3) recent progress on understanding the charge generation process in PSMA blend systems. Small molecule acceptors (SMAs) such as Y6 and their derivatives have been used in many high performance OSCs. One setback of such OSCs is that they are susceptible to thermal degradation. In this respect, using PSMAs in blends has been shown to be a possible strategy to not only prevent this degradation but could also overcome other stability issues such as light- and air-induced degradation. However, the efficiency of OSCs made with these PSMAs is generally lower than with SMA analogues, due mainly to the device photocurrent. In this study, we try to understand what is limiting the device photocurrent of PSMA based OSCs with spectroscopic instruments such as fs-TAS.


华南理工大学发光材料与器件国家重点实验室版权所有

地址:广东省广州市五山路381号华南理工大学北区科技园1号楼

电话:020-87113184 传真:020-87113184

邮箱:skllmd@scut.edu.cn