Yiben Fu Associate Professor (PI)
E-mail：yibenfu@scut.edu.cn
2024-Present South China University of Technology, Associate Professor
2018-2023 The JohnsHopkins University, Postdoctoral Researcher
2013-2018 Instituteof Physics, Chinese Academy of Sciences, Ph.D
2009-2013 Xi’an Jiaotong University, Bachelor
Devotedto developing computational methods to study biomolecular assembly and membraneremodeling, with the aim of elucidating their roles in crucial cellularprocesses, such as cell division, motility, transcriptional regulation, anddrug delivery.
Prof. Fu’s studies havefocused on protein self-assembly and protein-membrane interactions. Prof. Fudeveloped the nonequilibrium reaction-diffusion self-assembly simulator(NERDSS) based on single-particle reaction-diffusion algorithms. The softwarewas successfully applied to study the assembly of biomolecules, such asclathrin lattices and HIV gag capsids.Prof. Fu also implemented and developed a continuummembrane model to study membrane-associated protein-protein interactions andlarge-scale membrane remodeling with protein complexes like the clathrin cage.He has published more than 12 scientific papers on different top journals,including Nucleic Acids Research, Biophysical Journal, Journal of ChemicalPhysics, Current Opinion in Structural Biology etc.
1.Xi-Miao Hou#, Yi-BenFu#, Wen-Qiang Wu, Lei Wang, Fang-Yuan Teng, Ping Xie, Peng-YeWang and Xu-Guang Xi. Involvement of G-triplex and G-hairpin in themulti-pathway folding of human telomeric G-quadruplex. Nucleic Acids Research, 45, 11401 (2017).
2.Yi-Ben Fu, Yu-Ru Liu, Peng-Ye Wang and Ping Xie. A RevisedWorm-like Chain Model for Elasticity of Polypeptide Chains. Journal of Polymer Science, Part B: PolymerPhysics,56, 297-307 (2018).
3.Yi-Ben Fu, Si-Kao Guo, Peng-Ye Wang and Ping Xie. Dynamics ofcooperative cargo transport by two elastically coupled Kinesin-1 motors.The European Physical Journal E, 42, 41 (2019).
4.Yiben Fu, Osman N Yogurtcu, Ruchita Kothari, GudrunThorkelsdottir, Alexander J Sodt, Margaret E Johnson. An implicit lipid modelfor efficient reaction-diffusion simulations of protein binding to surfaces ofarbitrary topology. Journal of Chemical Physics, 151, 124115 (2019).
5.M.J. Varga#, YibenFu#, S. Loggia, O.N. Yogurtcu, and M.E. Johnson. NERDSS: anon-equilibrium simulator for multibody self-assembly at the cellular scale. BiophysicalJournal, 118, 3026 (2020).
6.Yiben Fu, Wade F. Zeno, Jeanne C. Stachowiak, Margaret E.Johnson. A continuum membrane model can predict curvature sensing by helixinsertion. Soft Matter, 17, 10649 (2021).
7.Yiben Fu, Margaret E. Johnson. Modeling membrane reshapingdriven by dynamic protein assemblies. Current Opinion in Structural Biology,78, 102505 (2023).