Academic Staff

Professor(PI)

YUAN ZHANG Professor(PI)
E-mail:
mczhang@scut.edu.cn

Education and Work Experience:

2019-present  South China University of Technology,Assistant Professor 

2016-2019  University of Rhode Island,Assistant Professor

2013-2016  Massachusetts Institute Technology,Postdoctoral Fellow

2009-2013  University of North Carolina,Chapel Hill,PhD

Research Direction:

Biological Pharmacy and Pharmaceutical Engineering

Research Achievement:

主要从事纳米药物和基因递送,免疫治疗和疫苗开发等方面的研究。多个科研项目得到了美国NIH等政府项目和基金会的资助。在Nature Communications, Biomaterials, Journal of Controlled Release, Molecular Therapy, ACS Nano, Nanoscale, Pharmaceutical Research, Molecular Pharmaceutics 等期刊发表论文20篇,其中一作9篇,通讯作者3篇,专著2部。美国及国际发明专利2项,中国发明专利1项。

The Selected Publications:

  1. Yuan Zhang*, Xin Bush, Bingfang Yan, Yue Zhang, Justin A.Chen, Gemcitabine nanoparticles promote antitumor immunity against melanoma. Biomaterials, 2019, 189,48-59. (*通讯作者,I区,IF=10.273)

  2. Yuan Zhang*, Na Li, Heikyung Suh, Darrell J. Irvine*, Nanoparticle anchoring targets immune agonists to tumors enabling anti-tumor efficacy without systemic toxicit. Nature Communications, 2018,9 (1): 6. (*共同通讯作者,I区,IF=11.878)

  3. YuanZhang, Lei Peng, Russell J.Mumper, Leaf Huang*, Combinational delivery of c-myc siRNA and nucleoside analogs in a single, synthetic nanocarrier for targeted cancer therapy. Biomaterials, 2013,34 (33): 8459-8468. (I区,IF=10.273)

  4. Jing Yao#, YuanZhang#, Srinivas Ramishetti, Yuhua Wang, Leaf Huang *, Turning an antiviral into an anticancer drug: nanoparticle delivery of acyclovir monophosphate. Journal of Controlled Release, 2013, 170 (3): 414-420. (#共同第一作者, I区,IF=7.901)

  5. YuanZhang, Nicole M. J. Schwerbrock, Arlin B.Rogers, William Y.Kim, Leaf Huang*, Codelivery of VEGF siRNA and gemcitabine monophosphate in a single nanoparticle formulation for effective treatment of NSCLC. Molecular Therapy, 2013, 21 (8): 1559-1569. (I区,IF=8.402)

  6. YuanZhang, William Y.Kim, Leaf Huang*, Systemic delivery of gemcitabine triphosphate via LCP nanoparticles for NSCLC and pancreatic cancer therapy. Biomaterials, 2013, 34 (13): 3447-58. (I区,IF=10.273)

  7. Yuan Zhang, Andrew Satterlee, Leaf Huang. In vivo gene delivery by nonviral vectors: overcoming hurdles? Molecular Therapy, 2012, 20 (7): 1298-304. (I区,IF=8.402)