CONGFEI XUProfessor(PI)
E-mail:
xucf@scut.edu.cn
Address:
C1-b409, Guangzhou International Campus
- Awardee of the National Youth Talent Program
- SCUT TCL Young Scholar
Website: https://www2.scut.edu.cn/nanomedicine/yjtdcy/list.htm
Website: https://www2.scut.edu.cn/nanomedicine/yjtdcy/list.htm
2025-present South ChinaUniversity of Technology, Professor
2019-2024 South China Universityof Technology, Associate Professor
2017-2019 South China Universityof Technology, Postdoctoral Fellow
2012-2017 University of Scienceand Technology of China, Ph.D
Drug delivery; Biomaterials; Geneediting; Gene therapy; Cancer immunotherapy
Research Achievement：
Specializes in nano-carrier constructionand bio-macromolecular drug delivery. With 50+ SCI-indexed publications,including 30+ as corresponding/first author in top-tier journals such as CellBiomaterials, Nature Communications, Science Bulletin, Advanced FunctionalMaterials, Nano Letters, and ACS Nano et al.; have filed 14 invention patents,with 4 granted; have led NSFC Excellent Young Scholars Program,
NSFC General Program, Guangdong OutstandingYoung Scholars Program et al.; Awarded the 2021 Guangdong Natural Science FirstPrize.
1.Yue Wang#, Min Yang#, Bao-Yue Zhang, Gui Zhao,Shi-Kun Zhou, Zi-Dong Lu, Cong-FeiXu*, Jun Wang*, Leveraging T-cell-specificfusogenicity of HIV for in vivo mRNA delivery to produce human CAR-T cells, Cell Biomaterials, 2025, 1, 100011.
2.Chaoran Chen, Yuxi Zhang, Ziyang Cao, Dongdong Li, Yueqiang Zhu, HoujinJing, Yan Li, Fangzheng Li, Cong-FeiXu*,Xianzhu Yang*, JunWang*, Long-TermStorage Stable Vesicle-Like Nanoparticles of Lipid and Polymer for siRNA andmRNA-Mediated Cancer Immunotherapy, AdvancedFunctional Materials, 2024, 34(44), 2406101.
3.Gui Zhao#, Yue Zhang#, Cong-Fei Xu*, Jun Wang*,In vivo production of CAR-T cells using virus-mimetic fusogenic nanovesicles, Science Bulletin, 2024, 69(3), 354−366.
4.Yue Wang#, Shi-Kun Zhou#, YanWang, Zi-Dong Lu, Yue Zhang, Cong-Fei Xu*, Jun Wang*,Engineering tumor-specific gene nanomedicine to recruit and activate T cellsfor enhanced immunotherapy, NatureCommunications, 2023, 14, 1993.
5.Yue Zhang#, Gui Zhao#, Jing Liu, Hou-Bing Zhang, Yue Wang, Ying-LiLuo, Zi-Dong Lu, Xiao-Jiao Du, Song Shen, Jin-Zhi Du, Cong-Fei Xu*,Jun Wang*, Gene-activating nanomedicine for thetumor-oriented infiltration of T cells to enhance immunotherapy against solidtumors, Nano Today, 2023, 52, 101992.
6.Yue Zhang#, Gui Zhao#, Yi-Fang Chen, Shi-KunZhou, Yue Wang, Yi-Qun Sun, Song Shen, Cong-Fei Xu*, Jun Wang*,Engineering nano-clusteredmultivalent agonists to cross-link TNF receptors for cancer therapy, Aggregate, 2023, 4(6), e393.
7.Jia Shi#, Meng-Wen Huang#, Zi-Dong Lu, Xiao-Jiao Du,Song Shen, Cong-Fei Xu*, Jun Wang*, Delivery ofmRNA for regulating functions of immune cells, Journal of ControlledRelease, 2022, 345, 494−511.
8.Yue Zhang#, Song Shen#, Gui Zhao, Cong-Fei Xu*, Hou-Bing Zhang, Ying-Li Luo,Zhi-Ting Cao, Jia Shi, Zhi-Bin Zhao, Zhe-Xiong Lian, Jun Wang*, In situ repurposing of dendritic cells withCRISPR/Cas9-based nanomedicine to induce transplant tolerance, Biomaterials,2019, 217, 119302.
9.Cong-Fei Xu#, Dong-Dong Li#, Zhi-Ting Cao, Meng-HuaXiong, Xian-Zhu Yang*, Jun Wang*, Facile hydrophobizationof siRNA with anticancer drug for non-cationic nanocarrier-mediated systemicdelivery, Nano Letters, 2019,19, 2688−2693.
10. Cong-Fei Xu#, Zi-Dong Lu#, Ying-Li Luo, Yang Liu, Zhi-Ting Cao, Song Shen,Hong-Jun Li, Jing Liu, Kai-Ge Chen, Zhi-Yao Chen, Xian-Zhu Yang, Zhen Gu, JunWang*, Targeting of NLRP3 inflammasome with gene editing for theamelioration of inflammatory diseases, Nature Communications, 2018, 9, 4092.