2017-Present  School of Biomedical Sciences and Engineering, South China University of Technology，Professor

2012-2017 National University of Singapore, Postdoctoral Research Fellow

2007-2012 University of Science and Technology of China, Ph.D

2003-2007 Anhui University

Nanomedicine and drug delivery systems, Biomedical materials, Bioimaging, Cancer diagnosis

Prof. Yuan Youyong, has been selected as high-level Introduction of Talent Scheme on July in 2017. His research directions are Nanomedicine and Drug Delivery Systems, Biomedical Materials, Bioimaging. Prof. Yuan has published over 50 papers in international significant journals, 5 of which have been listed in ESI highly cited papers and 2 of which have been cover reports. By the end of June of 2018, all of his paper has been cited over 2250 times, one of articled was cited more than 196 times which H index was 25. Prof. Yuan, who was to be key finisher applied two PCT patents.

1.    MaolinJiang, Ye Liu, Yansong Dong, Kewei Wang, and Youyong Yuan.* Bioorthogonal Chemistry and Illumination ControlledProgrammed Size-Changeable Nanomedicine for Synergistic Photodynamic andHypoxia-Activated Therapy, Biomaterials,2022, 284, 121480.

2.    YangyangZhao, Yansong Dong, Shuhan Yang, Yalan Tu, Chengbo Wang, Jun Li, Youyong Yuan,*Zhexiong Lian. Bioorthognal Equipping CAR-T Cells with Hyaluronidase andCheckpoint Blocking Antibody for Enhanced Solid Tumor Immunotherapy, ACS Central Science, 2022, 8, 603–614.

3.    KeweiWang, Maolin Jiang, Jielian Zhou, Ye Liu, Qingyu Zong, and Youyong Yuan.*Tumor-Acidity and Bioorthogonal Chemistry-Mediated On-Site Size TransformationClustered Nanosystem to Overcome Hypoxic Resistance and EnhanceChemoimmunotherapy, ACSNano, 2022, 16, 721–735.

4.    YalanTu, Xuan Xiao, Yansong Dong, Jisi Li, Ye Liu, Qingyu Zong, Youyong Yuan*,Cinnamaldehyde-based poly(thioacetal): AROS-awakened self-amplifying degradable polymer for enhanced cancerimmunotherapy, Biomaterials,2022, 289, 121795.

5.    KeweiWang, Xuan Xiao, Ye Liu, Qingyu Zong, Yalan Tu, Youyong Yuan*,Self-immolative polyprodrug-based tumor-specific cascade amplificated drugrelease nanosystem for orchestrated synergistic cancer therapy, Biomaterials, 2022, 289, 121803.

6.    KeweiWang, XuanXiao, Maolin Jiang, Jisi Li, Jielian Zhou, YouyongYuan.* An NIR-Fluorophore-Based Theranostic for Selective Initiation ofTumor Pyroptosis-Induced Immunotherapy, Small,2021, 17, 2102610.

7.    FangzhouYu,† Yalan Tu,†Shiwei Luo, Xuan Xiao, Wang Yao, Maolin Jiang, Xinqing Jiang,* Ruimeng Yang,* Youyong Yuan.* Dual-Drug Backboned Polyprodrug with aPredefined Drug Combination for Synergistic Chemotherapy,  NanoLetters, 2021, 21, 2216.

8.    XuanXiao,† Kewei Wang,† Qingyu Zong, YalanTu, Yansong Dong, YouyongYuan.* Polyprodrug with Glutathione Depletion and CascadeDrug Activation for Multi-drug Resistance Reversal, Biomaterials, 2021, 270, 120649.

9.    YalanTu, Yansong Dong, Kewei Wang, Song Shen, Youyong Yuan,* Jun Wang.* Intercellular Delivery ofBioorthogonal Chemical Receptors for Enhanced Tumor Targeting and Penetration, Biomaterials, 2020, 259, 120298.

10. Yansong Dong, Yalan Tu, Kewei Wang, Congfei Xu, Youyong Yuan,* Jun Wang.* A General Strategy forMacrotheranostic Prodrug Activation: Synergy by Tumor Acidic Microenvironmentand Bioorthogonal Chemistry. Angew.Chem. Int. Ed.,2020, 59, 7168-7172.