
2018-present Dean of School of Biomedical Sciences andEngineering, South China University of Technology
2016-2020 Institute of Life Sciences, South China UniversityofTechnology,Professor
2004-2016 Universityof Science and Technology of China,Professor
2002-2004 Johns Hopkins University USA, Postdoctoral fellow
1999-2002 Johns Hopkins Singapore, Postdoctoral fellow
1989-1998 Wuhan University, Ph.D.
Nanobiomedicine, drug delivery, tumor immunotherapy, mRNA vaccines
Prof.Wang, Outstanding Young Recipient of the National Natural Science Foundation ofChina, serving as the standing director of Chinese Society for Biomaterials,Fellow of the Royal Society of Chemistry(2016), Fellow of International Societyfor Biomaterials Science and Engineering(2020), Founding Fellow of the ChineseSociety for Biomaterials and deputy editor of journal Biomaterials. He haspublished 250 corresponding author research papers in Nat. Nanotechnol., Sci.Transl. Med., Nat. Commun., Proc. Natl. Acad. Sci. U. S. A., Angew. Chem. Int. Ed., etc. All papershave been cited more than 22600 times, with H-Index 81. He applied for morethan 40 invention patents, 22 of which were granted; the research‘nano-biomaterials for tumor microenvironment regulation’won the first prize ofnatural science in Guangdong Science and Technology Award in 2021 (firstfinisher); he presided over research projects such as National Key R&DProgram and National Natural Science Foundation of China Key Program.
List of representative papers:
[1]Mingdong Liu#, LiangqiHuang#, Weinan Zhang#, Xiaochuan Wang, Yuanyuan Geng, Yuhao Zhang, Li Wang,Wenbin Zhang, Yun-Jiao Zhang, Shiyan Xiao*, Yan Bao*, Menghua Xiong*, JunWang*, ATransistor-Like pH-Sensitive Nanodetergent for Selective Cancer Therapy, NatureNanotechnology, 2022, 17, 541-551.
[2]Gui Zhao#, Yue Zhang#,Cong-Fei Xu*, Jun Wang*, In VivoProduction of CAR-T Cells Using Virus-mimetic Fusogenic Nanovesicles, Science Bulletin, 2024, 69, 354-366.
[3]Kuirong Mao, Jialiang Wang,Qianyue Xie, Yong-Guang Yang, Song Shen, Tianmeng Sun, Jun Wang*, Cationic Nanoparticles-based Approaches for ImmuneTolerance Induction In Vivo, Journal ofControlled Release, 2024, 366, 425-447.
[4]Junbin Chen, Miao Su,Congfei Xu, Ziyang Cao, Xianzhu Yang*, JunWang*, Cationic Lipid-Polymer Hybrid Nanoparticle Drives in situ Generationand Lymphatic Navigation of Tumor Antigens to Prime Systemic AntitumorImmunity, Nano Today, 2024, 57,102335.
[5] Yansong Dong#, Ye Liu#,Yalan Tu, Youyong Yuan*, Jun Wang*,AIEgens Cross-linked Iron Oxide Nanoparticles Synchronously Amplify BimodalImaging Signals in Situ by Tumor Acidity-Mediated Click Reaction, Angewandte Chemie International Edition,2023, 62, e202310975.
[6]Yue Wang#, Shi-Kun Zhou#,Yan Wang, Zi-Dong Lu, Yue Zhang, Cong-Fei Xu*, Jun Wang*, Engineering Tumor-Specific Gene Nanomedicine to Recruitand Activate T Cells for Enhanced Immunotherapy, Nature Communications, 2023, 14, 1993.
[7]Yue Zhang#, Gui Zhao#, JingLiu, Hou-Bing Zhang, Yue Wang, Ying-Li Luo, Zi-Dong Lu, Xiao-Jiao Du, SongShen, Jin-Zhi Du, Cong-Fei Xu*, Jun Wang*,Gene-Activating Nanomedicine for the Tumor-Oriented Infiltration of T Cells toEnhance Immunotherapy against Solid Tumors, NanoToday, 2023, 52, 101992.
[8]Yansong Dong#, Yalan Tu#, YeLiu, Maolin Jiang, Emil Bulatov, Youyong Yuan*, Jun Wang*, Perivascular Nanocarriers Aggregation as Drug ReservoirsAugments Tumor Drug Delivery and Treatment Efficacy, Nano Today, 2023, 53,102004.
[9]Yue Zhang, Gui Zhao, Yi-FangChen, Shi-Kun Zhou, Yue Wang, Yi-Qun Sun, Song Shen, Cong-Fei Xu*, Jun Wang*, Engineering Nano-ClusteredMultivalent Agonists to Cross-Link TNF Receptors for Cancer Therapy, Aggregate, 2023, 4, e393.
[10]Mengwen Huang#, Songrong Wang#, Senbiao Chen#, Jilong Wang,Congfei Xu, Jing Liu, Zhexiong Lian*, Xiaojiao Du*, Jun Wang*, Pegylated Liposomal Mitoxantrone Modulates Tumor ImmuneLandscape to Boost PD-L1 Blockade Therapy, NanoToday, 2022, 44, 101500.
[11]Jia Shi#, Meng-Wen Huang#, Zi-Dong Lu, Xiao-Jiao Du, Song Shen,Cong-Fei Xu*, Jun Wang*, Delivery ofmRNA for Regulating Functions of Immune Cells, Journal of Controlled Release, 2022, 345, 494-511.
[12]Wei-Hai Chen, Qi-Wen Chen, Qian Chen, Chunyan Cui, Shun Duan,Yongyuan Kang, Yang Liu, Yun Liu, Wali Muhammad, Shiqun Shao, Chengqiang Tang,Jinqiang Wang, Lei Wang, Meng-Hua Xiong, Lichen Yin, Kuo Zhang, Zhanzhan Zhang,Xu Zhen, Jun Feng*, Changyou Gao*, Zhen Gu*, Chaoliang He*, Jian Ji*, XiqunJiang*, Wenguang Liu*, Zhuang Liu*, Huisheng Peng*, Youqing Shen*, Linqi Shi*,Xuemei Sun*, Hao Wang*, Jun Wang*,Haihua Xiao*, Fu-Jian Xu*, Zhiyuan Zhong*, Xian-Zheng Zhang*, Xuesi Chen*,Biomedical Polymers: Synthesis, Properties, and Applications, SCIENCE CHINA Chemistry, 2022, 65,1010-1075.
[13]Cheng-Tao Jiang#, Kai-Ge Chen#, An Liu, Hua Huang, Ya-Nan Fan,Dong-Kun Zhao, Qian-Ni Ye, Hou-Bing Zhang, Cong-Fei Xu, Song Shen*, Meng-HuaXiong, Jin-Zhi Du, Xian-Zhu Yang, JunWang*, Immunomodulating Nano-Adaptors Potentiate Antibody-Based CancerImmunotherapy, Nature Communications,2021, 12, 1359.
[14]Yansong Dong, Yalan Tu, Kewei Wang, Congfei Xu, Youyong Yuan*, Jun Wang*, A General Strategy forMacrotheranostic Prodrug Activation: Synergy between the Acidic TumorMicroenvironment and Bioorthogonal Chemistry. Angewandte Chemie International Edition, 2020, 59, 7168-7172.
[15]Hong-Jun Li#, Jing Liu#, Ying-Li Luo, Sen-Biao Chen, Rong Liu,Jin-Zhi Du*, Jun Wang*, IntratumorPerformance and Therapeutic Efficacy of PAMAM Dendrimers Carried by ClusteredNanoparticles. Nano Letter, 2019, 19,8947-8955.
[16]Hua Huang, Cheng-Tao Jiang, Song Shen*, An Liu, Yun-Jiu Gan,Qi-Song Tong, Sen-Biao Chen, Zhu-Xin Gao, Jin-Zhi Du, Jie Cao*, Jun Wang*, Nanoenabled Reversal ofIDO1-Mediated Immunosuppression Synergizes with Immunogenic Chemotherapy forImproved Cancer Therapy. Nano Letter,2019, 19, 5356-5365.
[17]Jin-Zhi Du*, Hong-Jun Li, JunWang*, Tumor-Acidity Cleavable Maleic Acid Amide (TACMAA): A Powerful Toolfor Designing Smart Nanoparticles to Overcome Delivery Barriers in CancerNanomedicine, Accounts of ChemicalResearch, 2018, 51, 2848-2856.
[18]Cong-Fei Xu#, Zi-Dong Lu#, Ying-Li Luo, Yang Liu, Zhi-Ting Cao,Song Shen, Hong-Jun Li, Jing Liu, Kai-Ge Chen, Zhi-Yao Chen, Xian-Zhu Yang,Zhen Gu, Jun Wang*, Targeting ofNLRP3 Inflammasome with Gene Editing for the Amelioration of InflammatoryDiseases, Nature Communications,2018, 9, 4092.
[19]Hong-Jun Li#, Jin-Zhi Du#, Xiao-Jiao Du#,Cong-Fei Xu, Chun-Yang Sun, Hong-Xia Wang, Zhi-Ting Cao, Xian-Zhu Yang, Yan-HuaZhu, Shu-Ming Nie*, Jun Wang*,Stimuli-responsive Clustered Nanoparticles for Improved Tumor Penetration andTherapeutic Efficacy, Proceedings of the National Academy of Sciences of theUnited States of America, 2016, 113, 4164-4169.
[20]Yan-Dan Yao#, Tian-Meng Sun#, Song-Yin Huang, Shuang Dou, LingLin, Jia-Ning Chen, Jian-Bin Ruan, Cheng-Qiong Mao, Feng-Yan Yu, Mu-Sheng Zeng,Jian-Ye Zang, Qiang Liu, Feng-Xi Su, Peter Zhang, Judy Lieberman*, JunWang*, Erwei Song*, Targeted Delivery of PLK1-siRNA by ScFvSuppresses Her2+ Breast Cancer Growth and Metastasis, Science TranslationalMedicine, 2012, 4, 130ra48 (Highlighted by Nature Review Cancer)
The Detail information of articles:http://www.researcherid.com/rid/F-9033-2011