Prof. &Dr. Dong Wei
Laboratory of Microalgal Biotechnology
School ofFood Science and Engineering
SouthChina University of Technology (SCUT)
WushanRoad 381
Guangzhou510640
P.R. China
OfficeTel: 86-20-87113849
Email: fewd304@scut.edu.cn; 975620779@qq.com
Website: http://www2.scut.edu.cn/food_en/2015/0716/c6186a94086/page.htm
EDUCATION
1997 Ph. D SugarEngineering, South China University of Technology (SCUT), Guangzhou, China
1993 M. Sc.Microbiology, Huazhong Agricultural University, Wuhan, Hubei, China
1988 B.Sc. Biology,Xinjiang University, Urumqi, Xinjiang
EMPLOYMENT HISTORY
11/2002- Professor,School of Food Science and Engineering, South China University of Technology,Guangzhou, P.R. China
07/1997-10/2002 Associate Professor, Collegeof Marine Life Sciences, the Ocean University of China, Qingdao, P.R. China
07/1993-08/1994Lecturer, Department of Food Sciences, South China Agricultural University,Guangzhou, Guangdong, P.R. China
07/1988-08/1990Research Assistant, Institute of Microbiology, Xinjiang Academy of AgriculturalSciences, Urumqi, Xinjiang, China
OVERSEAS RESEARCHEXPERIENCE
01/2019-02/2019 SeniorVisiting Professor, Institute for Inorganic and Analytical Chemistry BioorganicAnalytics, Friedrich-Schiller University Jena, Lessingstr. 8, Jena D-07743,Germany
11/2015-04/2016 SeniorVisiting Professor, Institute of Bioprocess and Biosystems Engineering, HamburgUniversity of Technology, Denickestr. 15, D-21073 Hamburg, Germany
09/2008-11/2009Visiting Professor, William G. Lowrie Department of Chemical and BiomolecularEngineering, the Ohio State University, Columbus, OH 43210, USA
07/2001-06/2002Visiting scholar, Department of Biology, the Hong Kong University of Sciencesand Technology, Hong Kong SAR, China
RESEARCHINTERESTS
• Physiology,biochemistry, omics study of microalgae for cell response to the environment
• Systematicbiology and engineering of microalgae for biotechnology
• High-cell-densityfermentation of microalgae for bioactive compounds and biomass production
• Carboncapture, nitrogen, and phosphate bioconversion for recycling utilizationthrough microalgal cultivation
SIGNIFICANT ROLES
Since 2021- Executive member, International Society of ChinaAlgae Association
Since 2016- Executive member, China Algae Association
Since 2010- Member, the Microalgae Branch of the ChineseSociety of Oceanic and Limnology
Since 2010- Member, Algae Biomass Submit
SELECTED PUBLICATIONSIN THE LAST TEN YEARS
48. Yang R, Wei D* and Pohnert G. Nitrogenutilization analysis reveals the synergetic effect of arginine and urea inpromoting fucoxanthin biosynthesis in the mixotrophic marine diatom Phaeodactylumtricornutum. Front. Mar. Sci. 2022, 9: 947726
47. Yu Liu, Dong Wei*, Weining Chen (2022). Oleaginous microalga Coccomyxasubellipsoidea as a highly effective cell factory for high CO2 fixation andhigh-protein biomass production by optimal supply of inorganic carbon andnitrogen. Frontiers in Bioengineering and Biotechnology 10:921024. doi:10.3389/fbioe.2022.921024
46. B. Zhu, D. Wei*, G.Pohnert, The thermoacidophilic red alga Galdieria sulphuraria is a highlyefficient cell factory for ammonium recovery from ultrahigh-NH4+industrial effluent with co-production of high-protein biomass byphoto-fermentation, Chemical Engineering Journal 438 (2022) 135598
45. Wang, Q., Wei, D.*, Luo, X., Zhu,J., Rong, J., Ultrahigh recovery rate of nitrate from synthetic wastewater by Chlorella-based photo-fermentation with optimallight-emitting diode illumination: From laboratory to pilot plant, Bioresource Technology 348 (2022) 126779
44. Liu, L.; Xie, M.; Wei, D*.Biological Detoxification of Mycotoxins: Current Status and Future Advances. Int.J. Mol. Sci. 2022, 23, 1064
43.Jun-Hui Chen, Dong Wei*, Phaik-EemLim, Jun Xie, Wei Ning Chen. Screening and effect evaluation of chemicalinducers for enhancing astaxanthin and lipid production in mixotrophic Chromochloris zofingiensis. Journal ofApplied Phycology 34(2022), 159-176
42. Qingke Wang, Zongyi Yu, DongWei *, Weining Chen, Jun Xie. Mixotrophic Chlorella pyrenoidosa ascell factory for ultrahigh-efficient removal of ammonium from catalyzerwastewater with valuable algal biomass coproduction through short-timeacclimation. Bioresource Technology 333 (2021)125151
41.Liu, L.#; Sanchez-Arcos, C#.; Pohnert, G.; Wei,D*. Untargeted Metabolomics Unveil Changes in Autotrophic and Mixotrophic Galdieria sulphuraria Exposed to High-LightIntensity. Int. J. Mol. Sci. 2021, 22, 1247
40. Wai-Kuan Yong, Kae-Shin Sim, Sze-WanPoong, Dong Wei, Siew-Moi Phang,Phaik-Eem Lim*. Interactive effects of warming and copper toxicity on atropical freshwater green microalga Chloromonasaugustae (Chlorophyceae). Journal of AppliedPhycology 33(2021), 67-77
39.Kai Peng, Xiaoying Chen, Dong Wei,Lirong Zhao, Bing Chen, Wenyan Mo, Chuntian Zheng, Yuping Sun*. Inclusion of Chlorellawater extract in Oreochromis niloticusfingerling diets: Effects on growth performance, body composition, digestiveenzyme activity, antioxidant and immune capacity, intestine and hepatichistomorphology and sodium nitrite stress resistance. Aquaculture Reports 18(2020) 100547
38.Runqing Yang, Dong Wei*. Improvingfucoxanthin production in mixotrophic culture of marine diatom Phaeodactylum tricornutum by LED lightshift and nitrogen supplementation, Frontiers of Bioengineering andBiotechnology. 2020，8：820
37. Qingke Wang, Zongyi Yu, Dong Wei*.High-yield production of biomass, protein and pigments by mixotrophic Chlorella pyrenoidosa through conversionof high ammonium in wastewater, Bioresource Technology 313 (2020)123499
36. Lei Qin, Dong Wei*. Transcriptome analysisreveals metabolic regulation mechanism of microalga Chlorella pyrenoidosa in response to the mixed culture with yeast Yarrowia lipolytica. Journal of AppliedPhycology (2020) 32, 2841–2849
35. Junhui Chen, Xiaoli Jiang, Dong Wei*, Effects of urea on cell growth and physiologicalresponse in pigment biosynthesis in mixotrophic Chromochloris zofingiensis, Journal of Applied Phycology (2020)32:1607-1618
34. Runqing Yang, Dong Wei*, Jun Xie. Diatomsas cell factories for high-value products: Chrysolaminarin, eicosapentenoicacid and fucoxanthin, Critical Review in Biotechnology 2020, 40, 7, 993–1009
33. Jun-hui Chen, Dong Wei*, Phaik-Eem Lim.Enhanced coproduction of astaxanthin and lipids by the green microalga Chromochloris zofingiensis: Selectedphytohormones as positive stimulators, Bioresource Technology 295 (2020) 122242
32. Yang, R.; Chen, G.; Peng, H.; Wei, D*. Identification andCharacterization of MiRNAs in Coccomyxasubellipsoidea C-169. Int. J. Mol. Sci. 2019, 20, 3448
31. Zhu, B., Wei, D.*, Luo, X., A novel alkalophilic Trebouxiophyte:Identification and its capability for CO2 capture and biomassproduction in high bicarbonate-based cultivation, Bioresource Technology 292(2019) 121952
30. Wai-Kuan Yong, Kae-Shin Sim, Sze-Wan Poong, Dong Wei, Siew-Moi Phang, Phaik-Eem Lim. Physiological and metabolic responses of Scenedesmus quadricauda (Chlorophyceae) to nickel toxicity and warming. 3 Biotech (2019) 9:315
29. Lei Qin, Lu Liu, Zhongming Wang, Weining Chen,Dong Wei*. The mixed culture of microalgae Chlorella pyrenoidosa and yeast Yarrowialipolytica for microbial biomass production. Bioprocess and BiosystemsEngineering (2019) 42:1409-1419
28. Jun-hui Chen, Lu Liu, Phaik-Eem Lim, DongWei*. Effects of sugarcane bagasse hydrolysate (SCBH) on cell growth and fattyacid accumulation of heterotrophic Chlorellaprotothecoides. Bioprocess and Biosystems Engineering (2019) 42:1129–1142
27. Lei Qin, Dong Wei*, Zhongming Wang,Mohammed Asraful Alam. Advantage assessment of mixed culture of Chlorella vulgaris and Yarrowia lipolytica for treatment ofliquid digestate of yeast industry and cogeneration of biofuel feedstock.Applied Biochemistry and Biotechnology(2019) 187:856–869
26.Wai-Kuan Yong, Kae-Shin Sim, Sze-Wan Poong, Dong Wei, Siew-Moi Phang, Phaik-Eem Lim*. Interactive effects oftemperature and copper toxicity on photosynthetic efficiency and metabolicplasticity of Scenedesmus quadricauda (Chlorophyceae).Journal of Applied Phycology (2018) 30:3029–3041
25.Xunya Jiang#, Lu Liu#, JinghuiChen, Dong Wei*. Effects of Xanthophyllomyces dendrorhouson cell growth, lipid and astaxanthin production of Chromochloris zofingiensis by mixedculture strategy. Journal of Applied Phycology (2018) 30:3009–3015
24. Zongyi Yu#, Lu Liu#, JunhuiChen, Xinpeng Wang, Dong Wei*.Effect of crude glycerol on heterotrophic growth of Chlorella pyrenoidosa and Coccomyxasubellipsoidea C-169. Journal of Applied Phycology (2018)30:2989–2996
23. Lu Liu, Jun-hui Chen, Phaik-EemLim, Done Wei*.Dual-species cultivation ofmicroalgae and yeast for enhanced biomass and microbial lipid production.Journal of Applied Phycology (2018) 30:2997-3007
22. Lei Qin, Lu Liu, Zhongming Wang, Weining Chen,Dong Wei*. Efficientresource recycling from liquid digestate by microalgae-yeast mixed culture andthe assessment of key gene transcription related to nitrogen assimilation inmicroalgae. Bioresource Technology 264 (2018) 90–97
21. Lu Liu, Junhui Chen, Phaik-Eem Lim, Dong Wei*. Enhanced singlecell oil production by mixed culture of Chlorella pyrenoidosa and Rhodotorula glutinisusing cassava bagasse hydrolysateas carbon source.BioresourceTechnology 255 (2018) 140-148
20. Chen, J-h., Liu, L., Wei, D.*, Enhanced production of astaxanthin by Chromochloriszofingiensis in a microplate-based culture system under high light irradiation,Bioresource Technology 245 (2017) 518–529
19.Qin, L., Liu, L., Zeng, A-P., Wei, D.*,From low-cost substrates to single cell oils synthesizedby oleaginous yeasts, Bioresource Technology 245 (2017)1507–1519
18.Zhu, B., Chen, G., Cao, X., Wei, D.*,Molecular characterization of CO2 sequestration and assimilation inmicroalgae and its biotechnological applications, Bioresource Technology 244 (2017)1207–1215
17. Junhui Chen, Dong Wei*, Georg Pohnert. Rapid estimation of astaxanthinand carotenoid-to-chlorophyll ratio in the green microalga Chromochloris zofingiensis using flow cytometry. Marine Drugs 2017, 15(7),231
16. Lu Liu, GeorgPohnert, Dong Wei*. Extracellularmetabolites from industrial microalgae and their biotechnological potential. Marine Drugs 2016,14(10), 191
15. Huifeng Peng, Dong Wei*, Gu Chen*, Feng Chen.Transcriptome analysis reveals global regulation in response to CO2supplementation in oleaginous microalga Coccomyxasubellipsoidea C-169. Biotechnology for Biofuels (2016) 9:151
14. Na Lu, Jun-hui Chen,Dong Wei*, Feng Chen, Gu Chen.Global metabolic regulation of the snow alga Chlamydomonas nivalis in response to nitrate or phosphatedeprivation by a metabolome profile analysis. Int. J. Mol. Sci. 2016, 17, 694
13. Huifeng Peng, DongWei*, Feng Chen, Gu Chen. Regulation of carbon metabolic fluxes in responseto CO2 supplementation in phototrophic Chlorella vulgaris: A cytomic and biochemical study. J Appl Phycol (2016)28:737–745
12. Qinglong Ding,Gu Chen *, Yuling Wang, Dong Wei.Identification of specific variations in a non-motile strain of cyanobacterium Synechocystis sp. PCC 6803 originatedfrom ATCC 27184 by whole genome resequencing. Int. J. Mol.Sci. 2015, 16, 24081-24093
11. Bo Yang, Jin Liu,Bin Liu, Peipei Sun, Xiaonian Ma, Yue Jiang, Dong Wei, Feng Chen*. Development of a stable genetic system for Chlorella vulgaris—A promising greenalga for CO2 biomitigation. Algal Research 12 (2015) 134-141
10. Chen, J., Liu, X., Wei, D.*, Chen, G., High yields offatty acid and neutral lipid production from cassava bagasse hydrolysate (CBH)by heterotrophic Chlorella protothecoides,Bioresource Technology 191 (2015)281-290
9. Bin Liu, Zheng Sun, Xiaonian Ma, Bo Yang, Yue Jiang, Dong Wei, Feng Chen*. Mutation breeding of extracellular polysaccharide-producing microalga Crypthecodinium cohnii by a novel mutagenesis withatmospheric and room temperature plasma. Int. J. Mol. Sci. 2015, 16, 8201-8212
8. Bin Liu, Jin Liu, Tianpeng Chen, Bo Yang, Yue Jiang, Dong Wei, Feng Chen*. Rapid characterization of fatty acids in oleaginous microalgae by near-infrared spectroscopy. Int. J. Mol. Sci. 2015, 16(4), 7045-7056
7. Lu N, WeiD*, Chen F, Yang S-T**, Lipidomic profiling reveals lipid regulation in thesnow alga Chlamydomonasnivalis in response to nitrate or phosphate deprivation, Process Biochemistry 48 (2013) 605-613
6. Tian-Qing Lan, Dong Wei*, Shang-Tian Yang*, Xiaoguang Liu. Enhanced production oflignocellulases by Trichoderma viridein a rotating fibrous bed bioreactor. Bioresource Technology 133 (2013) 175-182
5. DongWei, Xiaoguang Liu, Shang-Tian Yang*. Butyric acid production fromsugarcane bagasse hydrolysate by Clostridiumtyrobutyricum immobilized in a fibrous-bed bioreactor. BioresourceTechnology 129 (2013) 553-560
4. Na Lu, Dong Wei*,Xiao-Li Jiang, Feng Chen, Shang-Tian Yang**. Regulation of lipid metabolism insnow alga Chlamydomonas nivalis underNaCl stress: An integrated analysis by cytomicand lipidomic approaches. Process Biochemistry 47 (2012) 1163-1170
3. Na Lu, Dong Wei*, Xiao-Li Jiang, Feng Chen, Shang-Tian Yang**. Fatty AcidsProfiling and Biomarker Identification in Snow Alga Chlamydomonas nivalis under NaCl Stress Using GC/MS andMultivariate Statistical Analysis. Analytical Letters, 45: 1-12, 2012
2. Na Lu, DongWei*, Feng Chen, Shang-Tian Yang**. Lipidomic profilingand discovery of lipid biomarkers in snow alga Chlamydomonas nivalis under salt stress. Eur. J. Lipid Sci.Technol. 2012, 114, 253–265
1. Congcong Lu, JingboZhao, Shang-Tian Yang*, Dong Wei.Fed-batch Fermentation for n-Butanol Production from Cassava BagasseHydrolysate in a Fibrous Bed Bioreactor with Continuous Gas Stripping. Bioresource Technology104 (2012) 380-387
