Research Experience

• Mar. 2023 – Present       Professor, Spin-X Institute & School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou, China

• Sep. 2019 – Dec. 2022   Postdoctoral Research Fellow, Department of Radiology, Harvard Medical School/Massachusetts General Hospital, Boston, USA (Supervisor: Prof. Peter Caravan)

• Jul. 2019 – Sep. 2019     Research assistant, College of Chemistry and Molecular Engineering, Peking University, Beijing, China

Education Background

• Sep. 2014 – Jul. 2019   Ph. D. in Inorganic Chemistry, Peking University, Beijing (Supervisor: Prof. Jun-Long Zhang)

• Sep. 2011 – Jul. 2015    B.A in Economics, Renmin University of China, Beijing

• Sep. 2010 – Jul. 2014    B.Sc in Chemistry, Renmin University of China, Beijing

• Dec. 2012 – May 2013  Exchange student in Chemistry, McGill University, Montreal, Canada

Teaching Courses

• None for now.

Research

Dr. Ning’s research interests lie in the field that using chemistry tools to develop and translate metal-based complexes to diagnose and treat diseases in the early stage, helping to track molecular events in vivo and giving a guidance to clinic theranostic.  Dr. Ning has over 30 publications on high-impact journals, including 15 as the first(co-first) author. She is also the inventor of 5 issued patents, two of which have been transferred. Dr. Ning is reviewer of Angew. Chem. Int. Ed., Adv. Sci., Dalton Trans. etc and now serves in the Women in Molecular Imaging Network Leadership Committee. The lab has open positions for post-doc now.

Research Interests

• Bioinorganic chemistry

• Molecular imaging

• Translational medicine

Selected Publications

• Ning, Y.; Zhou, I. Y.; Robert, J. D.; Rotile, N. J.; Akam, E.; Barrett, S. C.; Sojoodi, M.; Barr, M. N.; Punshon, T.; Pantazopoulos, P.; Drescher, H. K.; Jackson, B. P.; Tanabe, K. K.; Caravan, P.* Molecular MRI quantification of extracellular aldehyde pairs for early detection of liver fibrogenesis and response to treatment. Sci. Trans. Med. 2022, 14, eabq6297
  https://doi.org/10.1126/scitranslmed.abq6297

• Ning, Y.; Zhou, I. Y.; Rotile, N. J.; Pantazopoulos, P.; Wang, H.; Barrett, S. C.; Sojoodi, M.; Tanabe, K. K.; Caravan, P.* Dual Hydrazine Equipped Turn-On Manganese-Based Probes for Magnetic Resonance Imaging of Liver Fibrogenesis. J. Am. Chem. Soc.2022, 144, 16553–16558.
  https://doi.org/10.1021/jacs.2c06231

• Ning, Y.; Huo, Y.; Xue, H.; Du, Y.; Yao, Y.; Kang, L.*; Sessler, J. L.* and Zhang, J.-L.* et al. Tri-Manganese(III) Salen-based Cryptands: A Metal Cooperative Antioxidant Strategy that Overcomes Ischemic Stroke Damage In Vivo. J. Am. Chem. Soc.2020, 142, 10219–10227. (highlighted by ChemistryViews)
  https://doi.org/10.1021/jacs.0c03805

• Ning, Y.; Liu, Y.-W.; Yang, Z.-S.; Yao, Y.; Kang, L.; Sessler, J. L.* and Zhang, J.-L.* Split and Use: Structural Isomers for Diagnosis and Therapy. J. Am. Chem. Soc.2020, 142, 6761-6768.
  https://doi.org/10.1021/jacs.0c01155

• Ning, Y.; Cheng, S.; Wang, J.; Liu, Y.-W.; Feng, W.; Li, F.*; Zhang, J.-L.* Fluorescence Lifetime Imaging of Upper Gastrointestinal pH In Vivo with a Lanthanide Based Near-Infrared τ Probe. Chem. Sci.2019, 10, 4227–4235.
  https://doi.org/10.1039/C9SC00220K

• Ning, Y.; Tang, J.; Liu, Y.-W.; Jing, J.*; Sun Y. and Zhang, J.-L.* Highly Luminescent, Biocompatible Ytterbium(III) Complexes as Near-Infrared Fluorophores for Living Cell Imaging. Chem. Sci.2018, 9, 3742-3753. (Selected as one of the most popular 2018-2019 chemical biology articles in Chemical Science)https://doi.org/10.1039/C8SC00259B

• Ning, Y.; Jin, G.-Q.; Zhang, J.-L.* Porpholactone Chemistry: An Emerging Approach to Bio-inspired Photosensitizers with Tunable Near-Infrared Photophysical Properties. Acc. Chem. Res.2019, 52, 2620-2633.
  https://doi.org/10.1021/acs.accounts.9b00119

• Ning, Y.; Zhu, M.; Zhang, J.-L.* Near-Infrared (NIR) Lanthanide Molecular Probes for Bioimaging. Coord. Chem. Rev.2019, 399, 213028.
  https://doi.org/10.1016/j.ccr.2019.213028

Issued Patents:

• Junlong Zhang, Jiyun Hu, Ronghui Liu, Yuanhong Liu, Yingying Ning, Xiaole Ma. Light-emitting material and preparation method therefor, WO2018120126A1, PCT/CN2016/113748.

• Junlong Zhang, Haoyan Yin, Yingying Ning, Bingwu Wang. Main group metal complexes and its preparation with cancer cell killing power and application, CN108676026A

• Junlong Zhang, Yingying Ning. Rare earth complex with near-infrared pH intensity and life response, CN 108424430B

• Junlong Zhang, Yingying Ning, Hengyu Lin, Bingwu Wang, Lei Kang, Yan Huo. Trinuclear Schiff base metal complex and preparation method and application thereof, CN 112442089B

• Junlong Zhang, Yingying Ning, Zishu Yang, Bingwu Wang. Near-infrared porphyrin compound and preparation method and application thereof, CN 112279862A

• 2021  World Molecular Imaging Congress
  “Young Investigator Award”, “Best Poster Award”
  “Women in Molecular Imaging Network Scholar Award”

• 2019   “Best Poster Award” in the 23rd  International Symposium on the Photochemistry and Photophysics of Coordination Compounds (ISPPCC)

• 2019   “100 Excellent Doctoral Thesis” and “Outstanding Graduate” in Peking University

• 2018  National Scholarship for graduates (The highest scholarship for Chinese graduates),   “Excellent Research Award” in Peking University

• 2017  Principal Scholarship in Peking University, “Dow Chemical Prize”