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基本信息
魏 东

学  位   博士

导师情况   博导

研究方向   工业生物技术

联系电话   020-87113849

Email     fewd304@scut.edu.cn

通讯地址   广州市天河区五山路381号华南理工大学13号楼304房



个人简介

1966.12月生,1997年获华南理工大学工学博士学位。曾在新疆农科院微生物所、华南农业大学食品系、中国海洋大学海洋生命学院工作。曾留学香港科技大学、美国俄亥俄州立大学、德国汉堡工业大学、德国弗莱德里希-席勒耶拿大学。现任华南理工大学食品科学与工程学院教授、博士生导师。研究领域为工业生物技术,主要针对富含生物活性物质和高效环境修复的微藻(酵母)优良种质,建立组学Omics)技术平台,在转录组、代谢组(脂组)、细胞组、藻际微生物组水平上,重点探索营养与环境因子对微藻与藻际微生物的作用机制、微藻光合作用和光发酵过程中碳氮磷高效生物转化及代谢调控机制的基础科学问题;在应用技术上,着重开发微藻(酵母)与藻际微生物组培养系统、微藻高密度(光)发酵、微藻户外大规模培养技术及其在生物转化积累植物蛋白、油脂、生物活性物质(类胡萝卜素、胞外多糖、藻胆蛋白)方面的调控技术,为微藻生物活性物质的开发、环境修复、三废(废水、废气、废渣)处理与资源化利用、生物饵料和生物饲料配料、生物能源的开发解决产业化关键技术。承担国家973863、国家自然科学基金、国家海洋局和广东省、广州市、中国石化等30余项科研项目,发表学术论文130多篇(其中SCI/EI收录论文60多篇)、授权专利10件。中国藻业协会理事、中国海洋与湖沼学会海洋生物技术分会理事和藻类分会理事。Energy Conversion and ManagementCritical Reviews in BiotechnologyBioresource TechnologyAlgal ResearchBioEnergy ResearchJournal of Agricultural and Food ChemistryJournal of the Taiwan Institute of Chemical EngineersProcess BiochemistryJournal of Applied Phycology24个国际期刊审稿人、澳大利亚阿德莱德大学博士论文评审人。


科研项目

1. 国家自然科学基金:CO2驱动胶球藻积累甘油三酯的脂组学变化及其机理研究, 31370383

2. 国家高技术研究发展计划(863)项目:利用污水培养微藻制备生物柴油关键技术,2013AA065802

3. 国家重点基础研究发展计划(973)项目:富油能源微藻的高通量筛选和系统评价,2011CB200901

4. 国家重点基础研究发展计划(973)项目: 能源微藻组学研究及生物标志物分子鉴定,2011CB200904

5. 国家海洋局海洋可再生能源专项资金项目:规模化培养海洋能源微藻制备生物柴油技术装备集成与示范,GHME2011SW04

6. 广东省教育部产学研结合重点项目:海洋饵料微藻规模培养与浓缩液系列产品开发及其应用示范,2011A090200073

7. 广东省海洋渔业科技与产业发展专项:海洋微藻功能制品多联产关键技术研发与水产应用,A201401C01

8. 广东省公益研究与能力建设项目:海洋硅藻高效培养制备岩藻黄素关键技术开发,2015A020216003

9. 广东省公益研究与能力建设项目:小球藻高产虾青素关键技术开发与集成,2016A010105001

10. 广州市科技计划项目产学研协同创新重大专项:利用酵母-微藻共培养系统处理水禽养殖废水及资源化利用示范,201704030084

11.中国石化项目:嗜酸嗜热红藻-小球藻两阶段耦合光发酵工艺处理高氨氮废水技术开发,36100002-19-FW2099-0035

12. 中石化项目:微藻脱硝组合工艺的工业示范218017-1

13. 中国石化项目:基于微藻培养的NaY分子筛高氨氮废液处理技术开发,36100002-18-FW2099-0043



学术论文

1. Jun-hui Chen, Dong Wei*, Phaik-Eem Lim. Enhanced coproduction of astaxanthin and lipids by the green microalga Chromochloris zofingiensis: Selected phytohormones as positive stimulators, Bioresource Technology 295 (2020) 122242 (2018 IF 6.669)

2. Yang, R.; Chen, G.; Peng, H.; Wei, D*. Identification and Characterization of MiRNAs in Coccomyxa subellipsoidea C-169. Int. J. Mol. Sci. 2019, 20, 3448. (2018 IF 4.183)

3. Zhu, B., Wei, D.*, Luo, X., A novel alkalophilic Trebouxiophyte: Identification and its capability for CO2 capture and biomass production in high bicarbonate-based cultivation, Bioresource Technology 292 (2019) 121952 (2018 IF 6.669)

4. Lei Qin, Lu Liu,Zhongming Wang, Weining Chen, Dong Wei*. The mixed culture of microalgae Chlorella pyrenoidosa and yeast Yarrowia lipolytica for microbial biomass production. Bioprocess and Biosystems Engineering (2019) 42:1409-1419 (2018 IF 2.139)

5. Jun-hui Chen, Lu Liu, Phaik-Eem Lim, Dong Wei*. Effects of sugarcane bagasse hydrolysate (SCBH) on cell growth and fatty acid accumulation of heterotrophic Chlorella protothecoides. Bioprocess and Biosystems Engineering (2019) 42:1129–1142 (2018 IF 2.139)

6. Lei Qin, Dong Wei*, Zhongming Wang, Mohammed Asraful Alam. Advantage assessment of mixed culture of Chlorella vulgaris and Yarrowia lipolytica for treatment of liquid digestate of yeast industry and cogeneration of biofuel feedstock. Applied Biochemistry and Biotechnology(2019) 187:856–869 (2018 IF 1.797)

7.Xunya Jiang#, Lu Liu#, Junhui Chen, Dong Wei*. Effects of Xanthophyllomyces dendrorhouson cell growth, lipid and astaxanthin production of Chromochloris zofingiensis by mixed culture strategy. Journal of Applied Phycology (2018) 30:3009–3015 (2018 IF 2.635)

8. Zongyi Yu#, Lu Liu#, Junhui Chen, Xinpeng Wang, Dong Wei*. Effect of crude glycerol on heterotrophic growth of Chlorella pyrenoidosa and Coccomyxa subellipsoidea C-169. Journal of Applied Phycology (2018) 30:2989–2996 (2018 IF 2.635)

9. Lu Liu, Jun-hui Chen, Phaik-Eem Lim, Done Wei*.Dual-species cultivation of microalgae and yeast for enhanced biomass and microbial lipid production. Journal of Applied Phycology (2018) 30:2997–3007 (2018 IF 2.635)

10. Lei Qin, Lu Liu, Zhongming Wang, Weining Chen, Dong Wei*. Efficient resource recycling from liquid digestate by microalgae-yeast mixed culture and the assessment of key gene transcription related to nitrogen assimilation in microalgae. Bioresource Technology 264 (2018) 90–97 (2018 IF 6.669)

11. Lu Liu, Junhui Chen, Phaik-Eem Lim, Dong Wei*. Enhanced single cell oil production by mixed culture of Chlorella pyrenoidosa and Rhodotorula glutinisusing cassava bagasse hydrolysate as carbon source.Bioresource Technology 255 (2018) 140-148 (2018 IF 6.669)

12. Chen, J-h., Liu, L., Wei, D.*, Enhanced production of astaxanthin by Chromochloris zofingiensis in a microplate-based culture system under high light irradiation, Bioresource Technology 245 (2017) 518–529. (2018 IF 6.669)

13. Qin, L., Liu, L., Zeng, A-P., Wei, D.*, From low-cost substrates to single cell oils synthesizedby oleaginous yeasts, Bioresource Technology 245 (2017) 1507–1519 (2019 IF 6.669)

14. Zhu, B., Chen, G., Cao, X., Wei, D.*, Molecular characterization of CO2 sequestration and assimilation in microalgae and its biotechnological applications, Bioresource Technology 244 (2017) 1207–1215 (2019 IF 6.669)

15. Junhui Chen, Dong Wei*, Georg Pohnert. Rapid estimation of astaxanthin and carotenoid-to-chlorophyll ratio in the green microalga Chromochloris zofingiensis using flow cytometry. Mar. Drugs 201715(7), 231 (2018 IF 3.772)

16. Lu Liu, Georg Pohnert, Dong Wei*. Extracellular metabolites from industrial microalgae and their biotechnological potential. Mar. Drugs 2016, 14(10), 191 (2018 IF 3.772)

17. Huifeng Peng, Dong Wei*, Gu Chen*, Feng Chen. Transcriptome analysis reveals global regulation in response to CO2 supplementation in oleaginous microalga Coccomyxa subellipsoidea C-169. Biotechnology for Biofuels (2016) 9:151 (2015 IF 6.44)

18. Na Lu, Jun-hui Chen, Dong Wei*, Feng Chen, Gu Chen. Global metabolic regulation of the snow alga Chlamydomonas nivalis in response to nitrate or phosphate deprivation by a metabolome profile analysis. Int. J. Mol. Sci. 2016, 17, 694. (2015 IF 3.25)

19. Chen, J., Liu, X., Wei, D.*, Chen, G., High yields of fatty acid and neutral lipid production from cassava bagasse hydrolysate (CBH) by heterotrophic Chlorella protothecoides. Bioresource Technology 191 (2015) 281-290 (2015 IF 4.91)

20. Huifeng Peng, Dong Wei*, Feng Chen, Gu Chen. Regulation of carbon metabolic fluxes in response to CO2supplementation in phototrophic Chlorella vulgaris: A cytomic and biochemical study. Journal of Applied Phycology (2016) 28:737745 (2015 IF 2.37)

21. Lu N, Wei D*, Chen F, Yang S-T**, Lipidomic profiling reveals lipid regulation in the snow alga Chlamydomonas nivalis in response to nitrate or phosphate deprivation. Process Biochemistry 48 (2013) 605-613 (2015 IF 2.529)

22. Tian-Qing Lan, Dong Wei*, Shang-Tian Yang*, Xiaoguang Liu. Enhanced production of lignocellulases by Trichoderma viridein a rotating fibrous bed bioreactor. Bioresource Technology 133 (2013) 175-182 (2015 IF 4.91)

23. Dong Wei, Xiaoguang Liu, Shang-TianYang*. Butyric acid production from sugarcane bagasse hydrolysate by Clostridium tyrobutyricum immobilized in a fibrous-bed bioreactor. Bioresource Technology 129 (2013) 553-560 (2015 IF 4.91)

24. Na Lu, Dong Wei*, Xiao-Li Jiang, Feng Chen, Shang-Tian Yang**. Regulation of lipid metabolism in snow alga Chlamydomonas nivalis under NaCl stress: An integrated analysis by cytomic and lipidomic approaches. Process Biochemistry 47 (2012) 1163-1170 (2015 IF 2.529)

25. Na Lu, Dong Wei*, Xiao-Li Jiang, Feng Chen, Shang-Tian Yang**. Fatty Acids Profiling and Biomarker Identification in Snow Alga Chlamydomonas nivalis under NaCl Stress Using GC/MS and Multivariate Statistical Analysis. Analytical Letters, 45: 1-12, 2012

26. Na Lu, Dong Wei*, Feng Chen, Shang-TianYang**. Lipidomic profiling and discovery of lipid biomarkers in snow alga Chlamydomonas nivalis under salt stress. Eur. J. Lipid Sci. Technol. 2012, 114, 253265

27. Congcong Lu, Jingbo Zhao, Shang-TianYang*, Dong Wei. Fed-batch Fermentation for n-Butanol Production from Cassava Bagasse Hydrolysate in a Fibrous Bed Bioreactor with Continuous Gas Stripping. Bioresource Technology 104 (2012) 380-387 (2015 IF 4.91)



获奖
教授

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