Zi-Dong Lu, Lecturer

Zi-Dong Lu, Lecturer

South China University of Technology

E-mail：luzd@scut.edu.cn

Education and Work Experience

2005-2010: Anhui Medical University, M.B., Clinical Pharmacology

2010-2011: King’s College London, University of London, M.Sc., Pharmacy

2012-2016: King’s College London, University of London, Ph.D., Pharmacy

2016-now: School of Medicine, South China University of Technology, Lecturer

Scientific Achievements

Z. D. Lu is mainly engaged in the delivery of nucleic acid drugs including siRNA with optimized cationic lipid-assisted nanoparticles (CLAN) for the treatment of tumor and immune-related diseases. She has published 4 articles in SCI journals, including Nature Communications, Biomaterials Science, European Journal of Medicinal Chemistry, Future Medicinal Chemistry etc.

Scientific Interests

RNAi, drug delivery, tumor and immune-related diseases

Publications

1. Cong-Fei Xu#, Zi-Dong Lu#, Ying-Li Luo, Yang Liu, Zhi-Ting Cao, Song Shen, Hong-Jun Li, Jing Liu, Kai-Ge Chen, Zhi-Yao Chen, Xian-Zhu Yang, Zhen Gu, Jun Wang*. Targeting of NLRP3 Inflammasome with Gene Editing for the Amelioration of Inflammatory Diseases. Nature Communications. 2018, 9, 4092. # (co-first author) (IF=12.353)

2. Yang Liu#, Gui Zhao#, Cong-Fei Xu*, Ying-Li Luo, Zi-Dong Lu*, Jun Wang, Systemic Delivery of CRISPR/Cas9 with PEG-PLGA Nanoparticles for Chronic Myeloid Leukemia Targeted Therapy. Biomaterials Science. 2018, 6, 1592-1603. *(co-corresponding author) （IF=5.831）

3. Yuan-Yuan Xie#, Zi-Dong Lu#, Xiao-Le Kong, Tao Zhou, Sukhi Bansal, Robert Hider*. Systematic Comparison of the Mono-, Dimethyl- and Trimethyl 3-Hydroxy-4(1H)-Pyridones - Attempted Optimization of the Orally Active Iron Chelator, Deferiprone. European Journal of Medicinal Chemistry. 2016, 115:132-140. # (co-first author) (IF=4.816)

4. Jun-Pei Li#，Zi-Dong Lu#，Xiao-Le Kong，Yong-Min Ma, Xing-Yuan Zhang, Sukhi Bansal, Vincenzo Abbate, Robert Hider*. Design and Synthesis of Novel Pegylated Iron Chelators with Decreased Metabolic Rate. Future Medicinal Chemistry. 2015, 7: 2439-2449. #(co-first author) (IF=3.969)