Professor, Institute of Life Sciences, School of Medicine, South China University of Technology
E-mail: yuanyy@scut.edu.cn
Professional Experience
2017.07-Now Professor, Institutes for Life Sciences, School of Medicine, South China University of Technology
Education
Anhui University, Hefei, China B.S. in Chemistry of Materials, 2003-2007
University of Science and Technology of China, Hefei, China Ph.D. in Polymer Chemistry and Physics, 2007-2012, degree conferred 2012
National University of Singapore, Singapore Department of Biomedical Engineering, Postdoctoral Research Fellow, 2012-2017
Honor
2007 Outstanding experts of Guangzhou award by Guangzhou Municipal People's Government
Teaching Activity
Polymer Chemistry; Biomedical Polymers
Research Interest
Polymer Chemisrty
Biomaterials and Drug Delivery
Fluorescence Imagng
SELECTED PUBLICATIONS
1. Yansong Dong, Yalan Tu, Kewei Wang, Congfei Xu, Youyong Yuan,* Jun Wang.* A General Strategy for Macrotheranostic Prodrug Activation: Synergy by Tumor Acidic Microenvironment and Bioorthogonal Chemistry. Angew. Chem. Int. Ed., 2020, 59. 7168-7172.
2. Kewei Wang, Yalan Tu, Wang Yao, Qingyu Zong, Xuan Xiao, Rui-Meng Yang,* Xin-Qing Jiang,* Youyong Yuan.* Size-Switchable Nanoparticles with Self-Destructive and Tumor Penetration Characteristics for Site-Specific Phototherapy of Cancer. ACS Appl. Mater. Interfaces, 2020, 12, 6933-6943.
3. Yansong Dong, Bin Liu,* Youyong Yuan.* AIEgen based drug delivery systems for cancer therapy. J. Control. Release, 2018, 290, 129-137.
4. Youyong Yuan, Chengqiong Mao, Xiaojiao Du, Jinzhi Du, Feng Wang and Jun Wang*, Surface Charge Switchable Nanoparticles based on Zwitterionic Polymer for Enhanced Drug Delivery to Tumor, Adv. Mater., 2012, 24, 5476-5480.
5. Youyong Yuan, Ryan T. K. Kwok, Ben Zhong Tang* and Bin Liu*, Targeted Theranostic Platinum (IV) Prodrug with a Built-in Aggregation-Induced Emission Light-up Apoptosis Sensor for Noninvasive Early Evaluation of its Therapeutic Responses In-situ, J. Am. Chem. Soc., 2014, 136, 2546-2554.
6. Youyong Yuan, Jie Liu and Bin Liu*, Conjugated Polyelectrolyte based Polyprodrug: Targeted and Imaging Guided Photodynamic and Chemotherapy with On-demand Drug Release upon Single Light Irradiation, Angew. Chem. Int. Ed., 2014, 53, 7163-7168.
7. Youyong Yuan, Chong-Jing Zhang, Meng Gao, Ruoyu Zhang, Ben Zhong Tang and Bin Liu*, Specific Light-up Bioprobe with Aggregation-Induced Emission and Activatable Photoactivity for Targeted and Image-Guided Photodynamic Ablation of Cancer Cells, Angew. Chem. Int. Ed., 2015, 54, 1780-1786.
8. Youyong Yuan, Chong-Jing Zhang and Bin Liu*, Photoactivatable AIE Polymer for Light Controlled Gene Delivery: Concurrent Endo-/Lysosomal Escaping and DNA Unpacking, Angew. Chem. Int. Ed., 2015, 54, 11419–11423.
9. Youyong Yuan, Shidang Xu, Xiamin Cheng, Xiaolei Cai and Bin Liu*, Bioorthogonal Turn-On Probe based on AIEgen for Cancer Cell Imaging and Ablation, Angew. Chem. Int. Ed., 2016, 55, 6457-6461.
10. Youyong Yuan, Chong-Jing Zhang, Ryan T. K. Kwok, Shidang Xu, Ruoyu Zhang, Jien Wu, Ben Zhong Tang* and Bin Liu*, Light-Up Probe for Targeted and Activatable Photodynamic Therapy with Real-Time In Situ Reporting of Sensitizer Activation and Therapeutic Responses, Adv. Funct. Mater., 2015, 25, 6586–6595.