杨显珠 教授
华南理工大学博士生导师
国家优秀青年基金科学基金获得者
电子邮箱：yangxz@scut.edu.cn
教育/工作经历
2017年4月-至今 华南理工大学 生物医学科学与工程学院 教授(博导)
2013年1月-2017年3月 合肥工业大学 医学工程学院 教授(博导)
2012年1月-2012年12月 中国科学技术大学 生命科学学院 博士后
2006年09月-2011年12月 中国科学技术大学 微尺度物质科学国家实验室 博士
2002年09月-2006年06月 合肥工业大学 化工学院 学士
研究方向
生物医用高分子材料；高分子药物载体；纳米医学
科研成果
通讯作者在Nature Communications、National Science Review、Advanced Functional Materials、ACS Nano、Nano Today等杂志发表论文60多篇；申请人的全部论文被引用9000余次；申请专利25项，已授权17项，转让2项。
代表性研究论文
1. Qiaoyi Huang#, Miao Su#, Liang Zhao#, Zhenghai Zhang, Yuxi Zhang, Xianzhu Yang*, Jun Wang*, NIR-II Light-Driven Genetically Edited Nanoparticles with Inherent CRT-Inducing Capability for Macrophage-Mediated Immunotherapy, Nano Today 2023, 50, 101857.
2. Ziyang Cao, Dongdong Li, Liang Zhao, Mengting Liu, Pengyue Ma, Yingli Luo, Xianzhu Yang*，Bioorthogonal in situ assembly of nanomedicines as drug depots for extracellular drug delivery, Nature Communications 2022, 13, 2038.
3. Liang Zhao,Dongdong Li, Yuxi Zhang, Qiaoyi Huang, Zhenghai Zhang, Chaoran Chen, Cong-Fei Xu, Xiao Chu, Yu Zhang, Xianzhu Yang*, HSP70 Promoter-Driven CRISPR/Cas9 System Activated by ROS for Multifaceted Anticancer Immune Response and Potentiated Immunotherapy, ACS Nano, 2022, 16, 13821−13833.
4. Wangcheng Zhang,# Yuxi Zhang,# Yingli Luo,# Senbiao Chen, Qiaoyi Huang, Zhiting Cao, Ming Liang, Xianzhu Yang*, A Nanoconfined Loading Strategy for Highly Efficient siRNA Delivery and Cancer Therapy, Nano Today 2022, 43, 101418.
5. Liangjie Jin#, Dongmei Yang#, Yonghong Song#, Dongdong Li* Weijia Xu Yueqiang Zhu, Cong-Fei Xu, Yang Lu*, Xianzhu Yang*, In Situ Programming of Nanovaccines for Lymph Node-targeted Delivery and Cancer Immunotherapy, ACS Nano 2022, 16, 15226−15236.
6. Yueqiang Zhu,# Yonghong Song,# Ziyang Cao, Liang Dong, Yang Lu,* Xianzhu Yang,* Jun Wang,* Magnetically Actuated Active Deep Tumor Penetration of Deformable Large Nanocarriers for Enhanced Cancer Therapy, Advanced Functional Materials, 2021, 31, 2103655.
7. Yuxi Zhang,# Zhenghai Zhang,# Senlin Li, Liang Zhao, Dongdong Li, Ziyang Cao, Xiaoding Xu, and Xianzhu Yang*, A siRNA-Assisted Assembly Strategy to Simultaneously Suppress “Self” and Upregulate “Eat-Me” Signals for Nanoenabled Chemo-Immunotherapy, ACS Nano, 2021, 15, 10, 16030-16042.
8. Junxia Wang,# Song Shen,# Jie Li, Ziyang Cao, Xianzhu Yang,* Precise Depletion of Tumor Seed and Growing Soil with Shrinkable Nanocarrier for Potentiated Cancer Chemoimmunotherapy, ACS Nano, 2021, 15, 3, 4636–4646
9. Senbiao Chen,# Dongdong Li,# Xiaojiao Du∗, Xinyu He, Mengwen Huang, Yang Wang, Xianzhu Yang∗, Jun Wang∗Carrier-free nanoassembly of doxorubicin prodrug and siRNA for combinationally inducing immunogenic cell death and reversing immunosuppression, Nano Today 2020, 35, 100924.
10. Yonghong Song,# Dongdong Li,# Yang Lu*, Kun Jiang, Yi Yang, Yunjun Xu, Liang Dong, Xu Yan, Daishun Ling, Xianzhu Yang*, and Shu-Hong Yu*, Ferrimagnetic mPEG-b-PHEP Copolymer Micelles Loaded with Iron Oxide Nanocubes and Emodin for Enhanced Magnetic Hyperthermia-Chemotherapy, National Science Review, 2020,7: 723-736.