都小姣 教授

广东省珠江人才计划青年拔尖人才

电子邮箱：duxjz@scut.edu.cn

招生方向

生物学、药学、基础医学

教育/工作经历

2023-至今   华南理工大学     医学院 教授

2016-2023   华南理工大学     医学院 副教授

2014-2016   中国科学技术大学   博士后

2009-2014   中国科学技术大学   生命科学学院 博士

2005-2009   郑州大学       生物技术系 学士

研究方向

纳米医学、mRNA疫苗

科研成果

在相关领域著名期刊Nano Today、PNAS、Adv. Mater.、Biomaterials等发表第一/通讯（含共同）作者论文15篇，主持国家自然科学基金面上项目等；参与国家重点研发计划等。

代表性研究论文

[1]      Mengwen Huang^#, Songrong Wang^#, Senbiao Chen^#, Jilong Wang, Congfei Xu, Jing Liu, Zhexiong Lian*, Xiaojiao Du*, Jun Wang*, Pegylated Liposomal Mitoxantrone Modulates Tumor Immune Landscape to Boost PD-L1 Blockade Therapy, Nano Today, 2022, 44, 101500.

[2]      Qingyu Zong, Jisi Li, Xuan Xiao, Xiaojiao Du*, YouyongYuan*, Self-amplified chain-shattering cinnamaldehyde-based poly(thioacetal) boosts cancer chemo-immunotherapy, Acta Biomaterialia, 2022, 154, 97-107.

[3]      Mengwen Huang, Miaomiao Zhang, Hongbin Zhu, Xiaojiao Du*, Jun Wang*, Mucosal vaccine delivery: A focus on the breakthrough of specific barriers, Acta Pharmaceutica Sinica B, 2022, 12, 3456-3474.

[4]      Jilong Wang, Mengwen Huang, Senbiao Chen, Yingli Luo, Song Shen, Xiaojiao Du*, Nanomedicine-mediated ubiquitination inhibition boosts antitumor immune response via activation of dendritic cells, Nano Research, 2021, 14, 3900-3906.

[5]      Senbiao Chen^#, Dongdong Li^#, Xiaojiao Du*, Xinyu He, Mengwen Huang, Yang Wang, Xianzhu Yang^∗, Jun Wang*, Carrier-free nanoassembly of doxorubicin prodrug and siRNA for combinationally inducing immunogenic cell death and reversing immunosuppression, Nano Today, 2020, 35, 100924.

[6]      Yang Wang^#, Zhu-Xin Gao^#, Xiaojiao Du*, Senbiao Chen, Wangcheng Zhang, Jilong Wang, Hongjun Li, Xinyu He, Jie Cao* and Jun Wang*, Co-inhibition of the TGF-β pathway and the PD-L1 checkpoint by pH-responsive clustered nanoparticles for pancreatic cancer microenvironment regulation and anti-tumor immunotherapy, Biomater. Sci., 2020, 8, 5121-5132.

[7]      Yan-Hua Zhu, Ji-Long Wang, Hou-Bing Zhang, Malik Ihsanullah Khan, Xiao-Jiao Du* and Jun Wang*, Incorporation of a rhodamine B conjugated polymer for nanoparticle trafficking both in vitro and in vivo, Biomater. Sci., 2019, 7, 1933-1939.

[8]      Ji-Long Wang, Xiao-Jiao Du*, Jin-Xian Yang, Song Shen, Hong-Jun Li, Ying-Li Luo, Shoaib Iqbal, Cong-Fei Xu, Xiao-Dong Ye, Jie Cao*, Jun Wang*, The effect of surface poly(ethylene glycol) length on in vivo drug delivery behaviors of polymeric nanoparticles, Biomaterials, 2018, 182, 104-113.

[9]      Xiao-Jiao Du, Ji-Long Wang, Shoaib Iqbal, Hong-Jun Li, Zhi-Ting Cao, Yu-Cai Wang, Jin-Zhi Du, and Jun Wang*, The Effect of Surface Charge on Oral Absorption of Polymeric Nanoparticles, Biomater. Sci., 2018, 6, 642-650.

[10]   Shoaib Iqbal, Xiaojiao Du*, Jilong Wang, Hongjun Li, Youyong Yuan, and Jun Wang, Surface charge tunable nanoparticles for TNF-α siRNA oral delivery for treating ulcerative colitis, Nano Res., 2018, 11, 2872-2884.