都小姣 教授
广东省珠江人才计划青年拔尖人才
电子邮箱：duxjz@scut.edu.cn
招生方向
基础医学（学博、学硕），生物医学工程（学博），生物学（学博、学硕）
教育/工作经历
2022.9-至今 华南理工大学 医学院 教授
2016.11-2022.8 华南理工大学 医学院 副教授
2014.6-2016.10 中国科学技术大学 博士后
2009.9-2014.6 中国科学技术大学 生命科学学院 博士
2005.9-2009.6 郑州大学 生物技术系 学士
研究方向
药物递送、肿瘤免疫治疗、mRNA疫苗
科研成果
在Nano Today、Journal of Controlled Release等共发表研究论文44篇，其中第一/通讯作者（含共同）论文18篇，申请中国发明专利6项，授权4项。主持国家自然科学基金面上项目等，2017年入选广东省“珠江人才计划”高层次人才青年拔尖人才，2021年获广东省自然科学奖一等奖（第三完成人）。
代表性研究论文
1.Mengwen Huang, Chuhao Wang, Xiaojuan Wang, Dandan Chen, Jin Ling, Yue Yu, Miaomiao Zhang, Yucai Wang, Congfei Xu, Song Shen, Xianzhu Yang*, Xiaojiao Du*, Jun Wang*, Two-step screening of lipid-polymer nanoparticles for efficient mRNA vaccine delivery and cancer immunotherapy, Nano Today, 2026, 67, 102943
2.Jin Ling#, Hongwei Chen#, Mengwen Huang#, Jun Wang*, Xiaojiao Du*, An mRNA vaccine encoding proteasome-targeted antigen enhances CD8+ T cell immunity, Journal of Controlled Release, 2025, 381, 113578.
3.Qingyu Zong, Jisi Li, Xuan Xiao, Xiaojiao Du*, Youyong Yuan*, Self-amplified chain-shattering cinnamaldehyde-based poly(thioacetal) boosts cancer chemo-immunotherapy, Acta Biomaterialia, 2022, 154, 97-107.
4.Mengwen Huang#, Songrong Wang#, Senbiao Chen#, Jilong Wang, Congfei Xu, Jing Liu, Zhexiong Lian*, Xiaojiao Du*, Jun Wang*, Pegylated liposomal mitoxantrone modulates tumor immune landscape to boost PD-L1 blockade therapy, Nano Today, 2022, 44, 101500.
5.Jilong Wang, Mengwen Huang, Senbiao Chen, Yingli Luo, Song Shen, Xiaojiao Du*, Nanomedicine-mediated ubiquitination inhibition boosts antitumor immune response via activation of dendritic cells, Nano Research, 2021, 14, 3900-3906.
6.Senbiao Chen#, Dongdong Li#, Xiaojiao Du*, Xinyu He, Mengwen Huang, Yang Wang, Xianzhu Yang∗, Jun Wang*, Carrier-free nanoassembly of doxorubicin prodrug and siRNA for combinationally inducing immunogenic cell death and reversing immunosuppression, Nano Today, 2020, 35, 100924.
7.Ji-Long Wang, Xiao-Jiao Du*, Jin-Xian Yang, Song Shen, Hong-Jun Li, Ying-Li Luo, Shoaib Iqbal, Cong-Fei Xu, Xiao-Dong Ye, Jie Cao*, Jun Wang*, The effect of surface poly(ethylene glycol) length on in vivo drug delivery behaviors of polymeric nanoparticles, Biomaterials, 2018, 182, 104-113.
8.Hong-Jun Li#, Jin-Zhi Du#, Xiao-Jiao Du#, Cong-Fei Xu, Chun-Yang Sun, Hong-Xia Wang, Zhi-Ting Cao, Xian-Zhu Yang, Yan-Hua Zhu, Shuming Nie*, Jun Wang*, Stimuli-responsive clustered nanoparticles for improved tumor penetration and therapeutic efficacy, Proc. Natl. Acad. Sci. U. S. A., 2016, 113 (15), 4164-4169.
9.Xiao-Jiao Du#, Ji-Long Wang#, Wei-Wei Liu#, Jin-Xian Yang, Chun-Yang Sun, Rong Sun, Hong-Jun Li, Song Shen, Ying-Li Luo, Xiao-Dong Ye*, Yan-Hua Zhu, Xian-Zhu Yang, Jun Wang*, Regulating the surface poly(ethylene glycol) density of polymeric nanoparticles and evaluating its role in drug delivery in vivo, Biomaterials, 2015, 69, 1-11.
10.Xian-Zhu Yang#, Xiao-Jiao Du#, Yang Liu, Yan-Hua Zhu, Yang-Zhong Liu, Ya-Ping Li, and JunWang*, Rational design of polyion complex nanoparticles to overcome cisplatin resistance in cancer therapy, Advanced Materials, 2014, 26, 931-936.