Name: Lei Junxia
Position title: Associate Professor
Address:
School of medicine, South china university of technology
Guangzhou Higher Education Mega Center
Guangzhou 510006
P. R. China
Tel: 86-20- 39380988
E-mail: leijx@scut.edu.cn
EDUCATION:
Doctor of Medicine in 2004Department of Pathophysiology
Zhongshan School of Medicine , Sun Yat-sen University
Master of Medicine in 1996Department of Microbiology and Immunology
Basic Medical College of Zhengzhou University
Bachelor of Medicine in 1992Department of Clinical Medicine
Basic Medical College of Zhengzhou University
POSITIONS:
2017,4-present
2016,9-2017,3
2016,3-2016-9
2004,7-2016,3Associate professor of School of medicine, South china university of technology, Guangzhou 510006
Lecturer of Department of Pathophysiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong 510089
Visiting scholar of University of Southern California
Lecturer of Department of Pathophysiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong 510089
1998,6-2001,9Lecturer of Department of Microbiology and Immunology, Basic Medical College, Zhengzhou University, Zhengzhou, Henan 450052.
1996,7-1998,5Assistant of Department of Microbiology and Immunology, Basic Medical College, Zhengzhou University, Zhengzhou, Henan 450052.
PROFESSIONAL ACTIVITIES:
1.Member of the Chinese Society of Pathophysiology
2.Member of the Chinese Society of Functional Science
RESEARCH FIELDS:
My research mainly focuses on effects of inflammatory microenvironment on mesenchymal stem cell(MSC)-mediated immune regulation and its use in the treatment of immuno-disorders.
PUBLICATIONS LIST(RECENT 5 YEARS):
1.Lei JX, Chen SL, Shuping Zhong. Abnormal expression of TFIIIB subunits and RNA Pol III genes is associated with hepatocellular carcinoma. 2017, 1-9.
2.Liao Y, Lei J(co-first author), Liu M, Lin W, Hong D, Tuo Y, Jiang MH, Xia H, Wang M, Huang W, Xiang AP*. Mesenchymal Stromal Cells Mitigate Experimental Colitis via Insulin-like GrowTh Factor Binding Protein 7-mediated Immunosuppression. Mol Ther, 2016 , 24(10):1860-1872.
3.Lei JX, Lu LH, Lin WJ. Searching for the use of virtual reality and real-time recording technique in the functional experiment. Chinese Journal of Medical Education Research. 2015;14(3):283-28 5.
4.Lei J(first author), Hui D(graduate), Huang W, Liao Y, Liu L, Zhang Q, Qi G, Song W, Xiang AP(corresponding author), Qing Zhou Q. Heterogeneity of the biological properties and gene expression profiles of murine bone marrow stromal cells. The International Journal of Biochemistry & Cell Biology. 2013 Nov;45(11):2431-43.
5.Lei J(first author), Wang Z, Hui D(graduate), Yu W, Zhou D, Xia W, Chen C, Zhang Q, Wang Z, Zhang Q, Xiang AP(corresponding author). Ligation of TLR2 and TLR4 on murine bone marrow-derived mesenchymal stem cells triggers differential effects on their immunosuppressive activity. Cell Immunol. 2011 Jun;271(1):147-56.
6.Lei J(first author), Wu ZhD.Teaching idea and teaching practice of general education course of “basic medicine introduction”. Journal of Shanxi Medical University(Preclinical Medical Education Edition). 2015;17(2):1-3.
7.Lei J(first author),Wang XJ,Wu ZHD. Curriculum and teaching practice of general education course of ‘ basic medicine introduction'in Sun Yat-sen University. Chinese Journal of Medical Education Research. 2013;12(2):121-123.
8.Lei J(first author),Wang XJ,Wu ZHD.Teaching practice of general education course in Sun Yat-sen University. Journal of Shanxi Medical University(Preclinical Medical Education Edition) . 2013;15(6):655-656.
9.Hui DY, Guo ZhY, Lu ZhJ, Yu WH, Wang T, Lei JX(correspondent). Biological Characteristics Analysis of Three Types of Murine Bone Marrow Mesenchymal Stem Cells. Journal of Sun yat-sen University(Medical Sciences) 2011;32(3):169-174.
10.Liu ShS,Lei JX, Li Y, Xiang P, Zhou DH. Isolation,identification and biological characteristics of mouse adipose-derived stromal cells. Journal of Sun yat-sen University(Medical Sciences)2012;33(3):299-304.
RESEARCH SUPPORT (RECENT 5 YEARS):
1.The inducing effect of MSC on the peritoneal macrophages and pulmonary macrophages and its implication for MSC-mediated immune regulation of IBD, Supported by Medical Scientific Research Foundation of Guangdong Province,China,A2014213(2014), PI:Junixa Lei
2.The role of TLR2/4 in MSC-mediated immune regulation of IBD,Supported by National Natural Science Foundation of China, 81170367 (2012), PI:Junixa Lei
3.Image production of human functional assay and its use in the pathophysiology teaching, Supported by laboratory research foundation of higher medical education of Guangdong Province,China , GDJ2014051 (2015), PI:Junixa Lei