教育/工作经历

2017-至今，华南理工大学教授，博士生导师

2010-2017，中国科学技术大学，生命科学学院，教授

2007-2010，约翰霍普金斯大学医学院，助理研究员

2005-2007，约翰霍普金斯大学医学院，博士后

2003-2005，美国国立癌症研究所，NCI/NIH免疫学部，博士后

1999-2003，日本大阪大学医学博士

1998-1999，日本大阪大学医学院访问学者

1989-1992，解放军军医进修学院（301医院）实验医学硕士

实验室研究方向

1. 肿瘤代谢调控的分子机制；

2. 非编码RNA对干细胞命运的调节作用

实验室科研成果

在 Nature、Cancer Cell、Nature Communications、cell Research、Nature Review Cancer、Cell metabolism、EMBO J、PNAS、Blood 等杂志发表论文50多篇，论文他引累计在3000次以上。2013年1月入选安徽百人计划特聘教授。目前承担国家科技部973计划重大研究课题（首席科学家）、中科院先导项目、国家自然科学基金课题等。

代表性研究论文

1. Wu, G.W., Yuan, M.Q., Shen, S.Q., Ma, X.Y., Fang, J.W., Zhu, L.B., Sun, L.C., Liu, Z.J., He, X.P., Huang, D., Li, T.T., Li, C.C., Wu, J., Hu, X., Li, Z.Y., Song, L.B., Qu, K., Zhang, H.F.*, Gao, P.* (2017). Menin enhances c-Myc-mediated transcription to promote cancer progression. Nature communications 8.

2. Wang, L.H., Zhang, T., Wang, L., Cai, Y.P., Zhong, X.Y., He, X.P., Hu, L., Tian, S.Y., Wu, M., Hui, L.J., Zhang, H.F.*, Gao, P.*(2017). Fatty acid synthesis is critical for stem cell pluripotency via promoting mitochondrial fission. EMBO J 36, 1330-1347.

3. Zhong, X.Y., Tian, S.Y., Zhang, X., Diao, X.W., Dong, F.T., Yang, J., Li, Z.Y., Sun, L.C., Wang, L., He, X.P., Wu, G.W., Hu, X., Wang, L.H., Song, L.B., Zhang, H.F., Pan, X., Li, A.L.*, Gao, P.*(2017). CUE domain-containing protein 2 promotes the Warburg effect and tumorigenesis. EMBO Rep 18, 809-825.

4. Sun, L.C., and Gao, P. (2017). Small molecules remain on target for c-Myc. Elife 6.e22915

5. Huang, D., Li, T.T., Wang, L., Zhang, L., Yan, R.H., Li, K., Xing, S.G., Wu, G.W., Hu, L., Jia, W.D., Lin, S. C., Dang, C. V., Song, L. B.*, Gao, P.*, Zhang, H. F.* (2016). Hepatocellular carcinoma redirects to ketolysis for progression under nutrition deprivation stress. Cell Research 26, 1112-1130.

6. Cao, Y., Guo, W.T., Tian, S.Y., He, X.P., Wang, X.W., Liu, X.M., Gu, K.L., Ma, X.Y., Huang, D., Hu, L., Cai, Y., Zhang, H.F., Wang, Y.M.*, and Gao, P.* (2015). miR-290/371-Mbd2-Myc circuit regulates glycolytic metabolism to promote pluripotency. EMBO J 34, 609-623.

7. Sun, L.C., Song, L.B., Wan, Q.F., Wu, G.W., Li, X.H., Wang, Y.H., Wang, J., Liu, Z.J., Zhong, X.Y., He, X.P., Shen, S. Q., Pan, X., Li, A. L., Wang, Y. L.,Gao, P.*, Tang, H. R.*, Zhang, H. F.* (2015). cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions. Cell Research 25, 429-444.

8. Ma, X.Y., Li, C.C., Sun, L.C., Huang, D., Li, T.T., He, X.P., Wu, G.W., Yang, Z., Zhong, X.Y., Song, L.B., Gao, P.*, Zhang, H.F.* (2014). Lin28/let-7 axis regulates aerobic glycolysis and cancer progression via PDK1. Nature communications 5.

9. Gao, P.*, Sun, L.C., He, X.P., Cao, Y., and Zhang, H.F. (2012). MicroRNAs and the Warburg Effect: New Players in an Old Arena. Curr Gene Ther 12, 285-291.

10. Gao, P.*, Tchernyshyov, I., Chang, T.C., Lee, Y.S., Kita, K., Ochi, T., Zeller, K.I., De Marzo, A.M., Van Eyk, J.E., Mendell, J.T., et al. (2009). c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism. Nature 458, 762-765.