Zeng, Wei

Introduction:

Name：Zeng Wei

Building No. 15
School of Chemistry and Chemical Engineering
South China University of Technology
Guangzhou 510641, China
e-mail: zengwei@scut.edu.cn
Professional
7/1994–9/1997, Assistant engineer, Institute of Chemical materials, China Academy of Engineering Physics
11/2009–Present, Professor, South China University of Technology
Education
10/2006-10/2008: The State University of New York at Buffalo, USA, Postdoctorate; Advisor: Sherry R. Chemler
3/2005–9/2006: The North Carolina State University, USA, Postdoctorate; Advisor: Christian Melander
1/2004–2/2005: The University of Hong Kong, HK, China, Research Assistant; Advisor: Vivian W. –W. Yam
9/2000 – 7/2003: Ph.D., Sichuan University, China; Advisor: Shengying Qin
9/1997 – 7/2000: M.S., Sichuan University, China; Advisor: Shengying Qin
9/1990 – 7/1994: B.S., Sichuan University, China; Advisor: Shengying Qin
Biography
Dr. Wei Zeng was born in Chongqing, China. He studied organic chemistry and received his bachelor, master, Ph.D. degrees at Sichuan University in 1994, 2000 and 2003, respectively. In 2004 he joined Professor V. W. W. Yam's lab at The University of Hong Kong where he worked as a Research Assistant on the synthesis of novel aza-thia crowned organometallic complexes. In 2005 he joined Professor C. Melander's group at The North Carolina State University where he worked as a postdoctorate on the DNA cleavage performance and the mechanism of action of diazobenzofluorene natural products. In 2006 he began another postdoctorate in Professor S. R. Chemler's lab at The State University of New York at Buffalo where he carried out Cu(II)- catalyzed asymmetric carboamination and the total synthesis of natural products. Dr. Zeng joined The School of Chemistry and Chemical Engineering at South China University of Technology as a full Professor in 2008, his research interests involve novel organic synthetic methodologies covering functional group transformations, metal-mediated chemistry, and asymmetric catalysis. He was a recipient of New Century Excellent Talents in University, Ministry of Education, China (2009).
Research Interest
. Organic Synthetic Methodology: Developing new transition-metal catalyzed organic reactions and studying their reaction mechanisms.
. Asymmetric Catalysis: Design, synthesis, and catalytic application of chiral ligands
Selected Major Research Programs
 The project of “Copper-catalyzed asymmetric diamination of alkenes” supported by National Natural Science Foundation of China (No. 21072063)
 The project of “Copper-catalyzed asymmetric reductive coupling of imines with inactive alkenes” supported by National Natural Science Foundation of China (No. 21372085)
 The project of “Synthesis of heterocyclic compounds” supported by Program for New Century Excellent Talents in University (No. NCET-10-0371)
 The project of “Green synthesis of chiral alpha-amino carboxylic acid derivatives” supported by West Light Foundation of The Chinese Academy of Sciences (No.Y3C1011100)
 The project of “Copper-catalyzed asymmetric synthesis of heyerocycles” supported Research Fund for the Doctoral Program of Higher Education of China (No. 20100172120020)
Selected Publications
25. Xie, Y,; Chen, TF.; Fu, SM.; Jiang, HF.; Zeng, W.* “Pd-Catalyzed Carbonylative Cycloamidation of Ketoimines for Synthesis of Pyrido [1, 2-a] Pyrimidin-4-Ones”, Chem. Commun. 2015, 51, 9377.
24. Zhang, W.; Wei, J.; Fu, SM.; Lin, D.; * Jiang, H.; Zeng, W.* “Highly Steroselective Ruthenium(II)-Catalyzed Direct C2-Syn-Alkenylation of Indoles with Alkynes”, Org. Lett. 2015, 17, 1349.
23. Liu, JZ.; Xie, Y.; Zeng, W *.; Lin, D.; Deng, Y.; Lu, X. * “Pd(II)-Catalyzed Pyridine N-Oxide-Directed Arylation of Unactivated Csp3-H bonds ”. J. Org. Chem. 2015, 80, 4618.
22. Fu, SM.; Yang, HH.; Li, GQ.; Deng, YF.; Jiang, HF.; Zeng, W*. “Copper(II)-Catalyzed Enantioselective Intramolecular Cyclization of N-Alkenyl Ureas”. Org. Lett. 2015, 17, 1018.
21. Li, MY.; Xie, Y.; Ye, Y*.; Zou, Y.; Jiang, HF.; Zeng, W*. “Cu(I)-Catalyzed Transannulation of N-Heteroaryl Aldehydes or Ketones with Alkylamines via C(sp3)-H Amination”, Org. Lett. 2014, 16, 6232.
20. Liang, LB.; Fu, SM.; Lin, D.; Zhang, XQ.; Deng, YF.; Jiang, HF.; Zeng, W*. “Ruthenium(II)- Catalyzed Direct Addition of Indole/Pyrrole C2-H Bonds to Alkynes”. J. Org. Chem. 2014, 79, 7492.
19. Fu, MQ.; Lin, DE.; Deng, YF.; Zhang, XQ.; Liu, YC.; Lai, CS.; Zeng, W*. “Pd-Catalyzed Tandem Homocupling- Adol- Dehydration of ortho-Acylphenyl Iodides”, RSC Adv. 2014, 4, 23595.
18. Qian, C.; Lin, DE.; Deng, YF.; Zhang, XQ.; Jiang, HF.; Miao, G.; Tang, XH.; Zeng, W*. “Palladium-catalyzed ortho-Functionalization of Azoarenes with Aryl Acylperoxides”, Org. Biomol. Chem. 2014, 12, 5866.
17. Xie, Y.; Chen, TF.; Fu, SM.; Li, XS.; Deng, YF.; Jiang, HF.; Zeng, W*. “Pd-Catalyzed [3 + 2] Cycloaddition of Ketoimines with Alkynes via Directed sp3 C-H Bond Activations”, Chem. Commun. 2014, 50, 10699.
16. Dang, L.; Liang, L. B.; Qian, C.; Fu, M. Q.; Ma, T. M*.; Xu, D. G*.; Jiang, H. F.; Zeng, W*. “Cu(OAc)2-Promoted Cascade Carboamination/Oxidative Cyclization of C-Acylimines with Alkenes”. J. Org. Chem. 2014, 79, 769.
15. Tang, H.; Qian, C.; Lin, D. E*.; Jiang, H. F.; Zeng, W*. “Palladium-Catalyzed Direct Oxidative C-H Cross-Coupling of Azoarenes with Alcohols”. Adv. Synth. Catal. 2014, 356, 519.
14. Xiong, F.; Qian, C.; Lin, D. E.; Zeng, W*.; Lu, X. X*. “Palladium-Catalyzed Cascade Oxidation/ sp2 C-H Acylation of Azoarenes with Aryl Methanes”. Org. Lett. 2013, 15, 5444.
13. Qian, C.; Chen, J. Y.; Fu, M. Q.; Zhu, S. Y.; Chen, W. H.; Jiang, H. F.; Zeng, W*. “An Unusual 1, 2-Aryl Shift in Palladium-Catalyzed Cross-Coupling Ethoxycarbonylation of Arylboronic Acids with -Iminoesters”. Org. Biomol. Chem. 2013, 11, 6013.
12. Zhu, S. J.; Lu, X. X.; Luo, YT.; Zhang, W.; Jiang, H. F.; Yan, M.; Zeng. W*. “Ruthenium(II)-Catalyzed Regioselective Reductive Coupling of α-Imino Esters with Dienes”. Org. Lett. 2013, 15, 1440.
11. Luo, Y. T.; Lu, X. X.; Ye, Y*.; Guo, Y.; Jiang, H. F.; Zeng, W*. “Pd-Catalyzed Tandem Cyclization of Ethyl Glyoxalate and Amines: Rapid Assembly of Highly Substituted Cyclic Dehydro-α-Amino Acid Derivatives”. Org. Lett. 2012, 14, 5640.
10. Chen, J. Y.; Lu, X. X.; Lou, W. Y.; Ye, Y.; Jiang, H. F.; Zeng, W*. “Pd(II)-Catalyzed Enantioselective Arylation of -Imino Esters”. J. Org. Chem. 2012, 77, 8541.
9. Fu, S. M.; Jiang, H. F.; Deng, Y. F.; Zeng, W*. “Palladium-Catalyzed Intramolecular Sulfonamidation/Oxidation of Imine: Access to Multifunctional Benzimidazoles”. Adv. Synth. Catal. 2011, 353, 2795.
8. Zhu, S. J.; Dong, J.; Fu, S. M.; Jiang, H. F.; Zeng, W*. “Cu(II)-Catalyzed Intermolecular Amidation of C-Acylimine: A Convenient Access to gem-Diamino Acid Derivatives”. Org. Lett. 2011, 13, 4914.
7. Zeng W.; Chemler, S. R*. “Total Synthesis of S-(+)-Tylophorine via Enantioselective Intramolecular Alkene Carboamination”. J. Org. Chem. 2008, 73, 6045.
6. Zeng W.; Chemler, S. R*. “Copper (II)-Catalyzed Enantioselective Intramolecular Carboamination of Alkenes”. J. Am. Chem. Soc. 2007, 129, 12948.
5. Huigens III, R. W.; Richards, J. J.; Parise, G.; Ballard, T. E.; Zeng W.; Deora, R.; Melander C*. “Inhibition of Pseudomonas aeruginosa Biofilm Formation with Bromoageliferin Analogues”. J. Am. Chem. Soc. 2007, 129, 6966.
4. Zeng W.; Ballard T. E.; Melander C*. “Mimicking the DNA Cleavage Activity of Kinamycin D with Electronically Tuned Diazofluorene analogs”. Bioorg. Med. Chem. Lett. 2006, 16, 5148.
3. Zeng W.; Ballard T. E.; Melander C*. “Tuning the Oxidation Properties of Vanadium (V) through Ligand Stoichiometry”. Tetrahedron Lett. 2006, 47(33), 5929.
2. Zeng W, Li J. Z, Mao Z. H, Hong Z, Qin S. Y*. “Synthesis, Oxygenation and Catalytic Oxidation Performance of Crown Ether Containing Schiff Base Transition - metal Complexes”. Adv. Synth. Catal. 2004, 346, 1385-1391.
1. Zeng W, Mao Z. H, Li J. Z, Qin S. Y*. “Synthesis of Novel Crowned Salicylaldimine Schiff Bases”. Synthesis 2004, 7, 1011.