药学(专业学位)

基本信息

石鹏特聘研究员
办公电话:
电子邮件:
pxs301@scut.edu.cn

教育与科研工作经历

2020—至今 华南理工大学 特聘研究员

2016—2020 美国宾夕法尼亚州立大学生物医学工程系 博士后

2010—2016  中国科学院长春应用化学研究所/中国科学院大学 博士

2006—2010 内蒙古大学学士

研究方向

细胞表面工程:

(1)设计开发生物材料用于哺乳细胞的功能化修饰和改造;

(2)探索改造后的细胞在细胞治疗中的应用;

(3)研究生物材料表面调控细胞行为

研究成果

累计发表学术论文21篇,申请美国发明专利2项,国际专利1项。其中第一作者论文10篇,包括Nat Commun(2 篇)、Angew Chem Int Ed(3 篇)、Adv Mater、Mater Today、Adv Funct Mater(2 篇)等国际著名学术期刊,研究成果被ChemistryViews、MaterialsViews、Nanowerk、Phys.org等多家媒体专题报道。获得Chinese Association for Biomaterials Trainee Award (2020)。

代表性论文:

  1. Peng Shi, Yong Wang*, Synthetic DNA for Cell Surface Engineering. Angew.Chem. Int. Ed.2020 (Under Revision)

  2. Peng Shi, Xuelin Wang, Brandon Davis, James Coyne, Cheng Dong, Joshua Reynolds, Yong Wang*, In situ synthesis of aptamer-based polyvalent antibody mimic on the cell surface for enhanced immune-cancer cell interactions. Angew.Chem. Int. Ed.2020, 59, 11892-11897 (IF=12.257)

  3. Peng Shi, Nan Zhao, James Coyne, Yong Wang*, DNA-templated Synthesis of Biomimetic Cell Wall on Mammalian Cells for Nanoencapsulation and Protection of Mammalian cells. Nat. Commun.2019, 10, 2223. (IF=11.878) (被Nanowerk、Phys.org、Newswise等亮点报道)

  4. Peng Shi, Nan Zhao, Jinping Lai, James Coyne, Erin Gaddes, Yong Wang*, Polyvalent Display of Biomolecules on Live Cells. Angew.Chem. Int. Ed. 2018, 57, 6800 –6804. (IF=12.257) (封面文章,被ChemistyViews报道“Viewing Biomolecules on Cellular Surfaces”)

  5. Peng Shi, Enguo Ju, Jiasi Wang, Zhengqing Yan, Jinsong Ren, and Xiaogang Qu*, Host–Guest Recognition on Photo-responsive Cell Surfaces Directs Cell–Cell Contacts. Mater. Today. 2017, 20(1), 16-21. (IF=24.372)

  6. Peng Shi, Enguo Ju, Zhengqing Yan, Nan Gao, Jiasi Wang, Jianwen Hou, Yan Zhang, Jinsong Ren, and Xiaogang Qu*, Spatiotemporal Control of Cell–Cell Reversible Interactions Using Molecular Engineering.Nat. Commun. 2016, 7, 13088. (IF=11.878)

  7. Peng Shi, Zhen Liu, Kai Dong, Enguo Ju, Jinsong Ren, Yingda Du, Zhengqiang Li, and Xiaogang Qu*, A Smart “Sense-Act-Treat” System: Combining a Ratiometric pH Sensor with a Near Infrared Therapeutic Gold Nanocage. Adv. Mater. 2014, 26, 6635-6641. (IF=25.809) (被 MaterialsViews报道“A Sense-Act-Treat System for Chemotherapy”)

  8. Peng Shi, Enguo Ju, Jinsong Ren and Xiaogang Qu*, Near-Infrared Light-Encoded Orthogonally Triggered and Logical Intracellular Release Using Gold Nanocage@Smart Polymer Shell. Adv. Funct. Mater. 2014, 24, 826–834. (IF=15.621)

  9. Peng Shi, Meng Li, Jinsong Ren and Xiaogang Qu*, Gold Nanocage-Based Dual Responsive “Caged Metal Chelator” Release System: Noninvasive Remote Control with Near Infrared for Potential Treatment of Alzheimer’s Disease. Adv. Funct. Mater. 2013, 23, 5412–5419. (IF=15.621) (封面文章,被 MaterialsViews、MaterialsViewsChina报道“Remote Controlled Drug Delivery”)