教职人员

基本信息

邵丹  特聘研究员(PI) 博士生导师  生物活性和仿生材料实验室
电子邮箱: shaodan@scut.edu.cn


教育与科研工作经历

2019—至今 华南理工大学 研究员

20162019 美国哥伦比亚大学生物医学工程系 博士后研究员

20152016 中国科学院苏州生物医学技术工程研究所 研究实习员

20102015 吉林大学基础医学院药理学医学博士

20062010 四川大学华西药学院药学理学学士


研究方向

生物活性材料、仿生材料、炎症性疾病诊治等

研究成果

致力于生物活性材料的开发并探索其在炎症性疾病诊治领域中的应用,近年来共发表SCI论文80余篇,其中以第一或通讯作者发表SCI论文40余篇,包括Nat.Rev. Mater., Sci. Adv., Adv. Mater., Angew. Chem. Int. Ed., Mater. Today, Adv.Funct. Mater., Adv. Sci., ACS Nano, Sig. Transduct. Target Ther., Nano Today和Biomaterials等国内外高影响力期刊, 其中8篇(曾)入围ESI高被引论文,10篇被选为期刊封面/内封面,总引用次数超5000次,Hindex=44,入选2023年度“全球前2%年度影响力顶尖科学家”;受邀担任Chin. Chem. Lett.和Research青年编委,并担任Adv. Mater., Adv. Sci. Adv. Funct. Mater.等多个高水平期刊审稿人。主持国家自然科学基金项目3项,申请中国发明专利10余项,获得获得广东省“珠江人才计划” 高层次人才称号和吉林省自然科学一等奖。


代表性论文:

1.Ruan F, Fang H, Chen F*, Xie X, He M, Wang R, Lu J, Wu Z, Liu J, Guo F,Sun W*, Shao D*. LeveragingRadiation-triggered Metal Prodrug Activation Through Nanosurface EnergyTransfer for Directed Radio-chemoimmunotherapy. Angewandte Chemie International Edition. 2023, 136: 2317943. (Inside Cover)

2.He Y, Cheng C, Liu Y, Chen F, Chen Y, Yang C*, Zhao Z, Dawulieti J, ShenZ, Zhang Y, Du J, Guan S*, Shao D*. IntravenousSenescent Erythrocyte Vaccination Modulates Adaptive Immunity and SplenicComplement Production. ACSNano. 2024, 18: 470.

3.Chen Y, Chen F, He X, Guo C, Cheng C, Wu Z, He Y, Zhang W, Cui F, Wang Y,Yang C*, Tang J*, Wang L, Shao D*. Myeloperoxidase-mimeticnanozyme generates hypochlorous acid for phagosomal bacteria elimination. Nano Today. 2024, 54: 102137.

4.Lu H, Ban Z, Xiao K, Sun M, Liu Y, Chen F, Shi T, Chen L, ShaoD*, Zhang M*, Li W*. Hepatic-accumulated obeticholic acid and atorvastatinself-assembled nanocrystals potentiate ameliorative effects in treatment ofmetabolic-associated fatty liver disease. Advanced Science. 2024, 11: 2308866.

5.Xu J, Xu J, Shi T, Zhang Y*, Chen F, Yang C, Guo X, Liu G, Shao D*, Leong K*, Nie G*. Probiotic-InspiredNanomedicine Restores Intestinal Homeostasis in Colitis by Regulating RedoxBalance, Immune Responses, and the Gut Microbiome. Advanced Materials. 2023, 35: 2207890.

6.Sun M, Chen P, XiaoK, Zhu X, Zhao Z, Guo C, He X, Shi T, Zhong Q, Jia Y, Tao Y, Li M*, Leong K*,Shao D*. Circulating Cell-free DNA as a Biomarkerand Therapeutic Target for Acetaminophen-Induced Liver Injury. Advanced Science. 2023, 10: 2206789.

7.Tu Z, Zhong Y,Hu H, Shao D*, Haag R, Schirner M, Lee J, Sullenger B, Leong K*.Design of therapeutic biomaterials to control inflammation. Nature Reviews Materials. 2022, 7: 557.(ESI高被引论文)

8.Shi C, Dawulieti J, Shi F, Chao Y, Qian Q, Shi T, Wang L, Hu H, Sun M, RenL, Chen F, Zhao Y, Liu F, Li M, Mu L, Liu D, Shao D*, Leong K*, She J*. Ananoparticulate dual scavenger for targeted therapy of inflammatory boweldisease. Science Advances.2022, 8: eabj2372.(ESI高被引论文)

9.Hu H, Yang C, LiM, Shao D*, Mao H, Leong K*. Flash technology-basedself-assembly in nanoformulation: Fabrication to biomedical applications. Materials Today. 2021, 42: 99-116.

10.Hu H, Yang C,Zhang F, Li M, Tu Z, Mu L, Dawulieti J, Lao Y, Xiao Z, Yan H, Sun W, Shao D*, Leong K*. A Versatile and Robust Platform for theScalable Manufacture of Biomimetic Nanovaccines. Advanced Science. 2021, 8:2002020.(内封面论文)

11.Dawulieti J, SunM, Zhao Y, Shao D*, Yan H, Lao Y, Hu H, Cui L, Lv X, Liu F, Chi C,Zhang Y, Li M, Zhang M, Tian H, Chen X, Leong K*, Chen L*. Treatment of SevereSepsis with Nanoparticulate Cell-free DNA Scavengers. Science Advances. 2020, 6: eaay7148.

12.ShaoD*, Zhang F, Chen F, Zheng X,Hu H, Yang C, Tu Z, Wang Z, Chang Z, Lu J, Li T, Zhang Y, Chen L, Dong W*,Leong K*. Biomimetic Diselenide-Bridged Mesoporous Organosilica Nanoparticlesas an X-ray-Responsive Biodegradable Carrier for Chemo-Immunotherapy. Advanced Materials. 2020, 32:2004385.(正封面论文)

13.Wang Z, Zhang F, Shao D*, Chang Z, Wang L, Hu H, Zheng X, Li X, Chen F, Tu Z, Li M, Sun W*, ChenL, Dong W*. JanusNanobullets Combine Photodynamic Therapy and Magnetic Hyperthermia toPotentiate Synergetic Anti-Metastatic Immunotherapy. Advanced Science. 2019, 6, 1901690.(ESI高被引论文,内封面论文)

14.Yan H, Shao D*, Lao Y, Li M, Hu H, Leong K*. Engineering of CellMembrane-based Nanotherapeutics to Target Inflammation. Advanced Science. 2019, 6: 1900605.(ESI高被引论文,正封面论文)

15.ShaoD, Li M, Wang Z, Zheng X, LaoY, Chang Z, Zhang F, Lu M, Yue J, Hu H, Yan H, Chen L, Dong W*, Leong K*.Bioinspired Diselenide-Bridged Mesoporous Silica Nanoparticles forDual-Responsive Protein Delivery. AdvancedMaterials. 2018, 30: 1801198. (ESI高被引论文,正封面论文)