张云娇 华南理工大学硕士生导师、广东省杰青获得者

Co-PI


张云娇副教授

华南理工大学硕士生导师

广东省杰青、   中科院优博获得者                   

电子邮箱:zhangyunjiao@scut.edu.cn

教育/工作经历

2017-至今,华南理工大学副教授,硕士生导师

2012-2016,中国科学技术大学生命科学学院,副研究员

2007-2012,中国科学技术大学,生化与分子生物学专业,博士

2003-2007,哈尔滨工业大学,生物工程专业,学士

科研成果

近年来,在Nature MaterialsNature CommunicationsNano LettersACS NanoAutophagy等国际一流期刊发表SCI论文近30篇,论文总引1968次,他引1748次。申请中国发明专利11项(已授权4项)及美国授权专利1项。主持国家自然科学基金面上、青年项目及广东省杰青项目,并参与“973”重大研究计划项目及珠江创新人才团队等多项

科研方向

纳米生物效应、纳米医学、肿瘤免疫治疗

个人代表论文

1. Zhang YJ, Zheng F, Yang T, Zhou W, Liu Y, Man N, Zhang L, Jin N, Dou Q, Zhang Y, Li Z, Wen LP*. Tuning the autophagy-inducing activity of lanthanide-based nanocrystals through specific surface-coating peptides. Nature Mater. 2012; 11(9):817-26. (2018 IF:39.235)

2. Zhang YJ, Sha R, Zhang L, Zhang W, Jin P, Xu W, Ding J, Lin J, Qian J, Yao G, Zhang R, Luo F, Zeng J*, Cao J*, Wen LP*.Harnessing copper-palladium alloy tetrapod nanoparticle-induced pro-survival autophagy for optimized photothermal therapy of drug-resistant cancer.Nature Commun. 2018;9(1):4236.(2018 IF:12.353)

3. Jin P#, Sha R#, Zhang YJ (co-first author)#, Liu L, Bian YP, J Qian J, Qian JY, Lin J, Ishimwe N, Hu Y, Zhang W, Liu YC, Yin SH, Ren L*, and Wen LP*.Blood Circulation-Prolonging Peptides for Engineered Nanoparticles Identified via Phage Display. Nano Letters. 2019;19(3):1467-1478.(2018 IF:12.080)

4. Yao H, Zhang YJ(Correspondence author) *, Liu L, Xu YC, Liu Xi, Lin J, Zhou W, Wei PF, Jin PP, Wen LP*. Inhibition of lanthanide nanocrystal-induced inflammasome activation in macrophages by a surface coating peptide through abrogation of ROS production and TRPM2-mediated Ca2+ influx. Biomaterials 2016; 108:143-156. (2018 IF:8.806)

5. Liu L, Sha R, Yang LJ, Zhao XM, Zhu YY, Gao JH*, Zhang YJ(Correspondence author) * and Wen LP*. Impact of morphology on iron oxide nanoparticles-induced inflammasome activation in macrophages. ACS Appl. Mater. Inter. 2018; 10 (48):41197-41206. (2018 IF:8.097)

6. Jin PP, Wei PF, Zhang YJ(Correspondence author) *, Lin J, Sha R, Hu Y, Zhang JQ, Zhou W, Yao H, Ren L*, Wen LP*. Autophagy-mediated Clearance of Ubiquitinated Mutant Huntingtin by Graphene Oxide. Nanoscale 2016;8(44):18740-18750. (2018 IF:7.233)

7. Zhou ZJ, Hu KW, Ma R, Yan Y, Ni B, Zhang YJ, Wen LP, Zhang Q*, Cheng YY*. Dendritic Platinum-Copper Alloy Nanoparticles as Theranostic Agents for Multimodal Imaging and Combined Chemophotothermal Therapy. Adv. Funct. Mater. 2016; 26(33): 5971–5978.

8. Klionsky DJ, Zhang YJ, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).Autophagy. 2016;12(1):1-222.

9. Lin J, Huang Z, Wu H, Zhou W, Jin P, Wei P, Zhang YJ, Zheng F, Zhang J, Xu J, Hu Y, Wang Y, Li Y, Gu N*, Wen LP*. Inhibition of autophagy enhances the anticancer activity of silver nanoparticles. Autophagy 2014;10(11):2006-20.

10. Miao Y, Xu J, Shen Y, Chen L, Bian Y, Hu Y, Zhou W, Zheng F, Man N, Shen Y, Zhang YJ, Wang M*, Wen LP*. Nanoparticle as signaling protein mimic: robust structural and functional modulation of CaMKII upon specific binding to fullerene C60 nanocrystals.ACS Nano 2014;8(6):6131-44.

地址:中国广州大学城华南理工大学医学院(生命科学研究院)B2楼  邮编:510006
电话(Tel)+86(0)20 39381182 电子邮箱:lifesciences@scut.edu.cn
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