都小姣 华南理工大学硕士生导师

Co-PI

都小姣副教授

华南理工大学硕士生导师


电子邮箱:duxjz@scut.edu.cn

教育/工作经历

2016-至今,华南理工大学,副教授,硕士生导师

2014-2016,中国科学技术,大学生命科学学院,博士后

2009-2014,中国科学技术大学,生命科学学院,生物材料专业,博士

2005-2009,郑州大学,生物工程系,生物技术专业,学士

科研成果

主要从事生物医用高分子材料和纳米生物医学研究,针对癌症治疗过程中,体内递送药物遇到的关键瓶颈,设计制备可综合克服药物递送障碍的纳米载体体系,并通过优化纳米载体的纳米特性,增强药物递送效率及抗癌效果。在相关领域著名期刊PNASAdv. Mater.Biomaterials等共发表SCI论文23篇,主持国家自然科学基金青年科学基金项目、广州市科学研究计划等,获得中国博士后科学基金面上及特别资助,作为研究骨干参与国家重点研发计划、“973”重大研发计划项目等。

科研方向

纳米药物载体、抗肿瘤研究

个人代表论文

1. Hong-Jun Li#, Jin-Zhi Du#, Xiao-Jiao Du (co-first author)#, Cong-Fei Xu, Chun-Yang Sun, Hong-Xia Wang, Zhi-Ting Cao, Xian-Zhu Yang, Yan-Hua Zhu, Shuming Nie*, Jun Wang*Stimuli-responsive clustered nanoparticles for improved tumor penetration and therapeutic efficacy Proceedings of the National Academy of Sciences,2016,113 (15), 4164-4169.

2. Xiao-Jiao Du#, Ji-Long Wang#, Wei-Wei Liu, Jin-Xian Yang, Chun-Yang Sun, Rong Sun, Hong-Jun Li, Song Shen, Ying-Li Luo, Xiao-Dong Ye*, Yan-Hua Zhu, Xian-Zhu Yang, Jun Wang*Regulating the surface poly(ethylene glycol) density of polymeric nanoparticles and evaluating its role in drug delivery in vivo Biomaterials, 2015, 69: 1-11.

3. Xian-Zhu Yang#, Xiao-Jiao Du (co-first author)#, Yang Liu, Yan-Hua Zhu, Yang-Zhong Liu, Ya-Ping Li, and JunWang *Rational design of polyion complex nanoparticles to overcome cisplatin resistance in cancer therapy Advanced Materials, 2014, 26: 931-936.

4. Hong-Jun Li#, Jin-Zhi Du*, Jing Liu, Xiao-Jiao Du, Song Shen, Yan-Hua Zhu, Xiaoyan Wang, Xiaodong Ye, Shuming Nie*, Jun Wang*Smart Superstructures With Ultrahigh pH-Sensitivity for Targeting Acidic Tumor Microenvironment: Instantaneous Size Switching and Improved Tumor Penetration ACS Nano, 2016, 10: 6753-6761.

5. Song Shen, Chun-Yang Sun, Xiao-Jiao Du, Hong-Jun Li, Yang Liu, Jin-Xing Xia*, Yan-Hua Zhu, Jun Wang*Co-Delivery of Platinum Drug and siNotch1 with Micelleplex for Enhanced Hepatocellular Carcinoma Therapy Biomaterials, 2015, 70: 71-83.

6. Shi Liang, Xian-Zhu Yang*, Xiao-Jiao Du, Hong-Xia Wang, Hong-Jun Li, Wei-Wei Liu, Yan-Dan Yao, Yan-Hua Zhu, Yin-Chu Ma, Jun Wang*, Erwei Song*Optimizing the Size of Micellar Nanoparticles for Efficient siRNA Delivery Advanced Functional Materials, 2015, 25: 4778-4787.

7. Song Shen, Xiao-Jiao Du, Jing Liu, Rong Sun, Yan-Hua Zhu, Jun Wang*Delivery of Bortezomib with Nanoparticles for Basal-like Triple-Negative Breast Cancer Therapy Journal of Controlled Release, 2015, 208: 14-24.

8. Meng-Hua Xiong#, Yan Bao#, Xiao-Jiao Du, Zi-Bin Tan, Qiu Jiang, Hong-Xia Wang, Yan-Hua Zhu, Jun Wang*Differential Anticancer Drug Delivery with A Nanogel Sensitive to Bacteria-Accumulated Tumor Artificial Environment ACS Nano, 2013, 7: 10636-10645.

9. You-Yong Yuan#, Chen-Qiong Mao#, Xiao-Jiao Du, Jin-Zhi Du, Feng Wang, Jun Wang*Surface Charge Switchable Nanoparticles based on Zwitterionic Polymer for Enhanced Drug Delivery to Tumor Advanced Materials, 2012, 24: 5476-5480.

10. Jin-Zhi Du, Xiao-Jiao Du, Cheng-Qiong Mao, Jun Wang*Tailor-made dual pH-sensitive polymer-doxorubicin nanoparticles for efficient anticancer drug delivery Journal of the American Chemical Society, 2011, 133: 17560-17563.

论文详细列表:

http://www.researcherid.com/rid/I-4579-2014

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