(Lecture) Grafting and Application of Electrospun Polymer Fibers
Topic: Grafting and Application of Electrospun Polymer Fibers
Speaker: Prof. Jem Kun CHEN (Taiwan University of Science and Technology)
Time: November 22, 2018 (Tuesday) 10:30
Venue: 324 lecture hall, No. 2 building, North Science Park, Wushan Campus
Thermo-sensitive affinity of the membrane with water resulted the average pore dimension responded to temperature changes. This report mainly introduces the grafting method of thermo-sensitive switching membrane and its application as protein valves. The thermo-sensitive switching membrane was prepared through grafting, using a click reaction, of an N-isopropylacrylamide (NIPAAm) derivative onto an electrospun poly (2,6-dimethyl-1,4-phenylene oxide) (PPO) fibrous membrane (EPFM). The PPO was first electrospun into a fibrous membrane, then brominated and reacted with NaN3 to generate the azido-terminated EPFMs. A PNIPAAm was synthesized and grafted onto the azido-terminated EPFMs. The surface roughness of PPO fibers was increased due to the presence of PNIPAAm grafts, such that the thermoresponse of the static water contact angle (SWCA) of PNIPAAm-grafted EPFMs between 25 and 45 °C was significantly greater than that of the same PNIPAAm grafted on a flat surface. Taking advantage of this temperature-responsive affinity, we applied the membranes as protein valves that blocked and released an antibody.
Jem Kun Chen is a professor of Department of Materials Science and Engineering, Taiwan University of Science and Technology. Prof. Chen received his Ph. D in applied Chemistry from Chiao-Tung University. Prof. Chen has won two-times Excellent Research Award of Taiwan University of Science and Technology and 8th Outstanding Professor Award of LCY Education Foundation. He has published more than 150 papers and declared 5 patents. His research interests focus on (1) Synthesis and application of stimuli-responsive polymers; (2) Electro- and magneto-rheology; (3) Electrospun fibers; (4) Plasmon crystals, grating, and photonic crystals; (5) Assay of Circulating Tumor Cells.
Announced by South China Advanced Institute for Soft Matter Science and Technology