(Lecture, Dec 1) Plasmonic Assays for Biomedical Uses
time: 2017-11-29


Title: Plasmonic Assays for Biomedical Uses
Speaker: Professor Liu Dingbin (Nankai University
Time: 3:00-4:00p.m., Dec. 1st, 2017
Venue: Room 214, Building No. 16, Wushan Campus
[Abstract]
Owing to its plasmon resonance effect, noble metallic nanoparticles show unique properties, by which we created a series of new assays. For instance, gold nanoparticles (AuNPs) show high extinction coefficients (108-1010 M-1cm-1, 3-5 orders of magnitude higher than those of organic dyes), which can be employed to construct colorimetric assays providing excellent detection sensitivity compared to those based on organic dyes. The distinct electromagnetic fields on metal surfaces enable them particular useful for developing surface-enhanced Raman scattering (SERS) assays with unmatched sensitivity and multiplex capability. We developed a series of background-free SERS assays for biological detection and molecular imaging with ultrahigh signal-to-background ratios (SBR). These novel platform methodologies could provide new avenues for optical detection and clinical diagnostics.