刘洋 教授（PI）

国家级青年人才项目入选者

办公地址：广州国际校区C1-b511

电子邮件:yaliu@scut.edu.cn

2023-至今 华南理工大学生物医学科学与工程学院 教授

2017-2023 维克森林大学医学院（美国）博士后

2011-2017 中国科学技术大学 博士

生物医学工程（学博、学硕）、生物学（学博、学硕）、药学（专硕）、材料与化工（工程博士）

纳米医学、药物递送载体、免疫治疗 

从事核酸及免疫激动剂等药物的纳米载体构建及其在肿瘤免疫治疗、炎症性疾病治疗等应用的研究。近年来共发表SCI论文27篇，包括Nat Nanotechnol、Nat Commun、Angew Chem Int Ed、J. Am. Chem. Soc、Adv Drug Deliv Rev、Adv Funct Mater、Biomaterials、J Controlled Release等国际知名期刊。撰写英文专著一部，申请国际发明专利一项，论文他引1400余次。主持国家海外引进人才青年项目。

代表性论文

1. Yang Liu, Lulu Wang, Qianqian Song,Muhammad Ali, William N. Crowe, Gregory L. Kucera, Gregory A. Hawkins, ShaySoker, Karl W. Thomas, Lance D. Miller, Yong Lu, Christina R. Bellinger, WeiZhang, Amyn A. Habib, W. Jeffrey Petty, Dawen Zhao, Intrapleural nano-immunotherapypromotes innate and adaptive immune responses to enhance anti-PD-L1 therapy formalignant pleural effusion, Nature Nanotechnology, 2022, 17:206-216

2. Yang Liu, William N.Crowe, Lulu Wang,Yong Lu, W.Jeffrey Petty, Amyn A.Habib, Dawen Zhao, An inhalablenanoparticulate STING agonist synergizes with radiotherapy to confer long-termcontrol of lung metastases, Nature Communications, 2019, 10:5108

3. Yang Liu,William N.Crowe, Lulu Wang, W. Jeffrey Petty, Amyn A. Habib, Dawen Zhao,Aerosolized immunotherapeutic nanoparticle inhalation potentiates PD-L1blockade for locally advanced lung cancer, Nano Research, 2022, https://doi.org/10.1007/s12274-022-5205-6

4. Yang Liu, Zhi-Ting Cao, Cong-Fei Xu,Zi-Dong Lu, Ying-Li Luo, Jun Wang, Optimization oflipid-assisted nanoparticlefor disturbing neutrophils-related inflammation, Biomaterials, 2018, 172:92-104

5. Yang Liu, Cong-Fei Xu, Shoaib Iqbal,Xian-Zhu Yang, Jun Wang, Responsive Nanocarriers as an Emerging Platform forCascaded Delivery of Nucleic Acids to Cancer, Advanced Drug Delivery Reviews,2017, 115: 98-114

6. Chun-Yang Sun, Yang Liu, Jin-Zhi Du, Zhi-TingCao, Cong-Fei Xu, Jun Wang, Facile Generation of Tumor-pH-LabileLinkage-Bridged Block Copolymers for Chemotherapeutic Delivery, AngewandteChemie-International Edition, 2016, 55: 1010-1014

7. Junxia Wang, Yang Liu, Yinchu Ma, Chunyang Sun, Wei Tao, Yucai Wang,Xianzhu Yang, Jun Wang, NIR-Activated Supersensitive Drug Release UsingNanoparticles with a Flow Core, Advanced Functional Materials, 2016,26: 7516-7525

8. Yang Liu, Gui Zhao, Cong-Fei Xu, Ying-Li Luo, Zi-Dong Lu, JunWang, Systemic delivery of CRISPR/Cas9 with PEG-PLGA nanoparticles for chronicmyeloid leukemia targeted therapy, Biomaterials Science, 2018, 6:1592-1603

9. Yang Liu,Yan-Hua Zhu, Cheng-Qiong Mao, Shuang Dou, Song Shen, Zi-Bin Tan, Jun Wang, Triplenegative breast cancer therapy with CDK1 siRNA delivered by cationic lipidassisted PEG-PLA nanoparticles, Journal of Controlled Release, 2014,192: 114-121

10. Yang Liu,Xin Wang, Chun-Yang Sun, Jun Wang , Delivery of Mitogen-Activated Protein KinaseInhibitor for Hepatocellular Carcinoma Stem Cell Therapy, ACS Applied Materials &Interfaces, 2015, 7: 1012-1020